Compound Summary

  Compound Information
 zidovudine

Compound Name:

zidovudine

Compound CID:

35370

Synonyms:

zidovudine

Azidothymidine

30516-87-1

3-Azido-3-deoxythymidine

Retrovir

More...

Iupac Name:

1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI:

InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1

InChIKey:

HBOMLICNUCNMMY-XLPZGREQSA-N

Canonical Smiles:

CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]

Isomeric Smiles:

CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]

Molecular Weight:

267.24

Molecular Formula:

C10H13N5O4

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 zidovudine

Molecular Weight:

267.24

Molecular Formula:

C10H13N5O4

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

3

Heavy Atom Count:

19

Complexity:

484

  Synonyms
 zidovudine

zidovudine zidovudine

zidovudine

Azidothymidine

30516-87-1

3-Azido-3-deoxythymidine

Retrovir

AZT

Thymidine, 3-azido-3-deoxy-

Zidovudinum

ZIDOVUDINE AZT

Compound S

Trizivir

Zidovudina

BW A509U

zidovudin

BWA509U

ZDV

UNII-4B9XT59T7S

Aztec

NSC 602670

BW-A509U

BW-A-509U

MFCD00006536

1-((2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE

CHEMBL129

1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine

1-(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl-5-methylpyrimidine-2,4-dione

MLS000028548

4B9XT59T7S

CHEBI:10110

3-Deoxy-3-azidothymidine

Azidothymidine (AZT)

NCGC00023945-05

Zidovudinum Latin

SMR000058351

Zidovudina Spanish

DSSTox_CID_127

DSSTox_RID_75386

DSSTox_GSID_20127

Propolis+AZT

1-(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

3-Azido-2,3-Dideoxythymidine

DRG-0004

Retrovir(TM)

AZT & Li & EPO

Retrovir (TN)

CCRIS 105

Cpd S

Intron A & AZT

HSDB 6515

Racemic Liposomal AZT

Liposomal AZT-SN-1

Liposomal AZT-SN-3

Zidovudine+PRO 140

PC-SOD+AZT

AZT & srCD4

AZT & rIFN.alpha.2

AZT & rsT4

rIFN-beta seron & AZT

3-Azido-3-deoxythymidine (AIDS)

AZT & EPO

AZT & GM-CSF

AZT & HPA

AZT & sCD4

AZT & SST

zudovidine

AZT & Li & GM-CSF

AZT+PRO 140

Met-SDF-1.beta. & AZT

AZT & Li & IL-1

AZT & Li & IL-6

AZT & IL-1

AZT & IL-2

AZT & IL-6

AZT & Interferon-.alpha.-2

AZT & Concanavalin A (ConA)

AZT & Lymphoblastoid Interferon

AZT & PM-19

Met-SDF-1.beta. & Zidovudine

4lhm

NSC-602670

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AZT)

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione AZT

AZT & rsCD4 & rIFN.alpha.A

3-azido-3-deoxythymidine, AZT

DS-4152 & AZT

1-(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl-5-methyl-pyrimidine-2,4-dione

AZT & Colony-stimulating factor 2

AZT & NP (from PHCA or HSA)

3-azido-thymidine

K7 P Ti2 W10 O40

Zidovudine USAN:USP:INN:BAN:JAN

Zidovudine & IFNL1

Zidovudine & IFNL2

Zidovudine & IFNL3

Zidovudine (Retrovir)

COMPOUND-S

3′-Azido-3′-deoxythymidine

Spectrum_001348

AZT & CD4(178)-PE 40

AZT & IFN.alpha.

Zidovudine & IL-29

Zidovudine & IL-28A

Zidovudine & IL-28B

AZT & Interleukin 29

Opera_ID_1602

Prestwick3_000333

Spectrum2_000927

Spectrum3_001507

Spectrum4_000332

Spectrum5_001101

3azido-3deoxythymidine"

3-Azido-3-deoxythymidine & Erythropoietin"

3-Azido-3-deoxythymidine & Sho-Saiko-To

Azidothymidine; Zidovudine

Interferon AD + 3-azido-3-deoxythymidine

AZT & Interleukin 28A

AZT & Interleukin 28B

3-Azido-3-deoxythymidine & Concanavalin A"

3-Azido-3-deoxythymidine & Interleukin-1"

3-Azido-3-deoxythymidine & Interleukin-2"

3-Azido-3-deoxythymidine & Interleukin-6"

3-azido3-deoxythymidine

AZT & IFNL1

AZT & IFNL2

AZT & IFNL3

1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione

AZT & Interferon lambda-1

AZT & Interferon lambda-2

AZT & Interferon lambda-3

3-Deoxy-3-azidothymidine

BSPBio_000365

BSPBio_003153

KBioGR_000703

KBioSS_001828

MLS001055351

MLS001076358

MLS002153202

MLS002222249

Zidovudine & Interleukin 29

DivK1c_000524

SPECTRUM1502109

3-deoxy-3-azido-thymidine

SPBio_000834

Zidovudine & Interleukin 28A

Zidovudine & Interleukin 28B

AZT & IL-28A

AZT & IL-28B

BPBio1_000403

GTPL4825

Zidovudine (JP17/USP/INN)

3-Azido-3-deoxythymidine & Lithium & Erythropoietin"

3-Azido-3-deoxythymidine & Lithium & Interleukin-1"

3-Azido-3-deoxythymidine & Lithium & Interleukin-6"

3-Azido-3-deoxythymidine & Lymphoblastoid Interferon

DTXSID8020127

SCHEMBL14615088

SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

AZT & IL-29

HMS501K06

KBio1_000524

KBio2_001828

KBio2_004396

KBio2_006964

KBio3_002653

3-Azido-3-deoxythymidine & Heteropolyoxotungstate PM-19

racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)

3-Azido-3-deoxy-thymidine

NINDS_000524

Zidovudine & Interferon lambda-1

Zidovudine & Interferon lambda-2

Zidovudine & Interferon lambda-3

HMS1921J20

HMS2090G11

HMS2092D06

HMS2096C07

HMS2234K17

HMS3259H17

HMS3713C07

Pharmakon1600-01502109

ZINC3779042

3azido-23-dideoxythymidine

Tox21_110062

Tox21_110894

Tox21_202203

Tox21_300578

BBL033764

BDBM50002692

CCG-39924

CZ0012

NSC758185

STK801891

AKOS005622576

AKOS015842610

Tox21_110062_1

3-azido-2,3-dideoxythymidine

DB00495

MCULE-8664408343

NC00666

NSC-758185

IDI1_000524

NCGC00014918-01

NCGC00023945-03

NCGC00023945-04

NCGC00023945-06

NCGC00023945-07

NCGC00023945-08

NCGC00023945-09

NCGC00023945-10

NCGC00023945-12

NCGC00023945-13

NCGC00023945-24

NCGC00023945-25

NCGC00178237-01

NCGC00178237-02

NCGC00254276-01

NCGC00259752-01

1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

AS-13019

SBI-0051731.P002

AB0012841

Propolis & Thymidine, 3-azido-3-deoxy-

S2579

SW198799-2

EN300-52518

3-Azido-3-deoxythymidine, >=98% (HPLC)

C07210

D00413

D88500

J10271

3-Azido-3deoxythymidine & Interferon .alpha."

3-Azido-3-deoxythymidine, >=99.0% (HPLC)

A820413

Q198504

SR-01000000098

SR-05000001587

J-700147

SR-01000000098-3

SR-05000001587-1

BRD-K72903603-001-04-6

BRD-K72903603-001-14-5

Z1723414428

Zidovudine, European Pharmacopoeia (EP) Reference Standard

3-Azido-3-deoxythymidine & Recombinant Interferon-.alpha.-2

Zidovudine, United States Pharmacopeia (USP) Reference Standard

3-Azido-3-deoxythymidine & CD4-Pseudomonas exotoxin A hybrid"

Beta interferon(rIFN-beta seron) & 3-Azido-3-deoxythymidine(AZT)"

Lecithinized superoxide dismutase & Thymidine, 3-azido-3-deoxy-"

3-Azido-2,3-dideoxythymidine & sCD4(soluble recombinant protein)"

Sulfated polysaccharide-peptidoglycan DS-4152 & 3-Azido-3-deoxythymidine"

Thymidine, 3-azido-3-deoxy- & PRO 140 (Anti-CCR5 monoclonal antibody)

Zidovudine, Pharmaceutical Secondary Standard; Certified Reference Material

(AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

(AZT)1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(AZT)

3-Azido-3-deoxythymidine & Granulocyte-macrophage colony-stimulating factor"

3-Azido-3-deoxythymidine & Lithium & Granulocyte-macrophage colony-stimulating factor"

3-Azido-3deoxythymidine & Recombinant Soluble CD4 & Recombinant Interferon.alpha.A

4-(4-Azido-5-hydroxy-tetrahydro-furan-2-yl)-5-methyl-3H-pyrazine-2,6-dione

Met-Stromal Cell-derived Factor-1.beta. (Human) & 3-Azido-3-deoxythymidine

1-((2R,4S,5S)-4-(diazoamino)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

1-((2R,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

1-((2S,4R,5R)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AzddThd, AZT)

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (N3ddThd)

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(3-azido-2,3-dideoxythymidine)

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(azidothymidine, AZT)

1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(Zidovudine, AZT)

146426-54-2

3-Azido-3deoxythymidine & Nanoparticles (from human serum albumin or polyhexylcyanoacrylate)

3-((2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)triaz-1-en-2-ium-1-ide

3-Azido-1,2,3-trideoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-D-erythro- pentofuranuronic acid
  Experimental Data
 zidovudine

Species Dosage Unit CG Lifespan(AVG/MED days) TG Lifespan(AVG/MED days) Lifespan Change(AVG/MED%) CG Lifespan(MAX days) TG Lifespan(MAX days) Lifespan Change(MAX%) Significant Strain Gender PubMed Active Label
Caenorhabditis elegans 33 umol/L 8 NS N2 24134630 Inactive
Caenorhabditis elegans 50 umol/L 11 25 127.3 S N2 34227219 Active
  Experimental Data Visualization
 zidovudine

  Statistics Data
 zidovudine

Species Lifespan Change(AVG/MED%) Lifespan Change(MAX%) Count Reference Count Data point
Caenorhabditis elegans 127.3 2 2
  Statistics Data Visualization
 zidovudine

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