Compound Summary
Compound Information
glipizide
Compound Name: | glipizide |
Compound CID: | 3478 |
Synonyms: | glipizide 29094-61-9 Glucotrol Glydiazinamide Melizide More... |
Iupac Name: | N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide |
InChI: | InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28) |
InChIKey: | ZJJXGWJIGJFDTL-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3 |
Isomeric Smiles: | CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3 |
Molecular Weight: | 445.5 |
Molecular Formula: | C21H27N5O4S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
glipizide
Molecular Weight: | 445.5 |
Molecular Formula: | C21H27N5O4S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 31 |
Complexity: | 697 |
Synonyms
glipizide
| glipizide | glipizide |
|---|---|
glipizide |
29094-61-9 |
Glucotrol |
Glydiazinamide |
Melizide |
Glibenese |
Glucozide |
Glupizide |
Sucrazide |
Dipazide |
Glupitel |
Mindiab |
Minidiab |
Minodiab |
Napizide |
Ozidia |
Glucotrol XL |
Glibetin |
Glucolip |
Aldiab |
Digrin |
Glican |
Glidiab |
Glipid |
Minidab |
Glyde |
Gluco-Rite |
Glipizida |
Glipizidum |
Glipizidum INN-Latin |
Glipizida INN-Spanish |
K 4024 |
Metaglip |
CP 28720 |
K-4024 |
N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-5-methylpyrazine-2-carboxamide |
TK 1320 |
CP-28720 |
CP 28,720 |
UNII-X7WDT95N5C |
N-2-4-(cyclohexylcarbamoylsulfamoyl)phenylethyl-5-methylpyrazine-2-carboxamide |
Glipizide (Glucotrol) |
MFCD00072159 |
Glide |
CHEMBL1073 |
X7WDT95N5C |
1-Cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)urea |
CP-28,720 |
MLS000069386 |
N-2-(4-{(cyclohexylcarbamoyl)aminosulfonyl}phenyl)ethyl-5-methylpyrazine-2-carboxamide |
CHEBI:5384 |
CP 28720;K 4024 |
N-(2-{4-(cyclohexylcarbamoyl)sulfamoylphenyl}ethyl)-5-methylpyrazine-2-carboxamide |
N-(4-(beta-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N-cyclohexylurea |
Pyrazinecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl- |
NCGC00015462-07 |
SMR000058455 |
CAS-29094-61-9 |
1-cyclohexyl-3-p-2-(5-methylpyrazinecarboxamido)ethylphenylsulfonylurea |
DSSTox_CID_20676 |
DSSTox_RID_79535 |
Urea, 1-cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)- |
DSSTox_GSID_40676 |
29094-66-4 |
1-cyclohexyl-3-({p-2-(5-methylpyrazinecarboxamido)ethylphenyl}sulfonyl)urea |
N-{4-beta-(5-methylpyrazine-2-carboxamido)ethylbenzenesulphonyl}-N-cyclohexylurea |
Glucotrol (TN) |
Pyrazinecarboxamide, N-2-4-(cyclohexylamino)carbonylaminosulfonylphenylethyl-5-methyl- |
Glipizide (USP/INN) |
SR-01000000010 |
EINECS 249-427-6 |
BRN 0903495 |
Glipizide, solid |
N-(4-N-(cyclohexylcarbamoyl)sulfamoylphenethyl)-5-methylpyrazine-2-carboxamide |
Glipizide USAN:USP:INN:BAN |
glipizide/glucotrol |
Glipizide,(S) |
Prestwick_242 |
KS-1068 |
Metaglip (Salt/Mix) |
Lopac-G-117 |
Opera_ID_1908 |
Prestwick0_000131 |
Prestwick1_000131 |
Prestwick2_000131 |
Prestwick3_000131 |
G-117 |
CBiol_001788 |
Lopac0_000621 |
SCHEMBL17094 |
BSPBio_000202 |
BSPBio_001349 |
KBioGR_000069 |
KBioSS_000069 |
MLS001148176 |
BIDD:GT0476 |
SPBio_002141 |
BPBio1_000224 |
GTPL6821 |
DTXSID0040676 |
KBio2_000069 |
KBio2_002637 |
KBio2_005205 |
KBio3_000137 |
KBio3_000138 |
Bio1_000074 |
Bio1_000563 |
Bio1_001052 |
Bio2_000069 |
Bio2_000549 |
HMS1361D11 |
HMS1568K04 |
HMS1791D11 |
HMS1989D11 |
HMS2089C21 |
HMS2093J09 |
HMS2095K04 |
HMS2233N11 |
HMS3259K12 |
HMS3261N04 |
HMS3369L12 |
HMS3402D11 |
HMS3655G04 |
HMS3712K04 |
Pharmakon1600-01505433 |
ZINC537795 |
BCP09195 |
HY-B0254 |
Tox21_110156 |
Tox21_301834 |
Tox21_500621 |
BBL028143 |
BDBM50012956 |
NSC759120 |
s1715 |
STK631952 |
AKOS005564405 |
N-4-(3-Cyclohexylureidosulfonyl)phenethyl-5-methyl-2-pyrazinecarboxamide |
Tox21_110156_1 |
CCG-204710 |
DB01067 |
LP00621 |
MCULE-5142805548 |
NC00564 |
NSC 759120 |
NSC-759120 |
SDCCGSBI-0050603.P003 |
1-Cyclohexyl-3-{4-2-(5-methylpyrazine-2-carboxamido)ethylphenylsulfonyl}urea |
IDI1_033819 |
N-2-4-(cyclohexylcarbamoylsulfamoyl)phenylethyl-5-methyl-pyrazine-2-carboxamide |
Glipizide 100 microg/mL in Acetonitrile |
NCGC00015462-01 |
NCGC00015462-02 |
NCGC00015462-03 |
NCGC00015462-04 |
NCGC00015462-05 |
NCGC00015462-06 |
NCGC00015462-08 |
NCGC00015462-09 |
NCGC00015462-10 |
NCGC00015462-11 |
NCGC00015462-12 |
NCGC00015462-14 |
NCGC00015462-23 |
NCGC00016802-01 |
NCGC00023748-03 |
NCGC00023748-04 |
NCGC00023748-05 |
NCGC00023748-06 |
NCGC00023748-07 |
NCGC00255522-01 |
NCGC00261306-01 |
AC-15789 |
SBI-0050603.P002 |
AB0012143 |
EU-0100621 |
FT-0626714 |
FT-0659737 |
G0369 |
ST50826363 |
SW196549-3 |
D00335 |
094G619 |
Q3108899 |
SR-01000000010-2 |
SR-01000000010-5 |
W-107005 |
BRD-K12219985-001-04-8 |
BRD-K12219985-001-15-4 |
Z1880962274 |
Glipizide, European Pharmacopoeia (EP) Reference Standard |
Glipizide, United States Pharmacopeia (USP) Reference Standard |
Glipizide, Pharmaceutical Secondary Standard; Certified Reference Material |
1-cyclohexyl-3-(4-(2-(2-methylpyrazine-5-carboxamido)ethyl)phenylsulfonyl)urea |
1-Cyclohexyl-3-{{p=2-5-methylpyrazine-carboxamido)-ethylphenyl}sulphonyl}urea |
1-Cyclohexyl-3-4-2-(5-methylpyrazine-2-carboxamido)ethylphenylsulfonylurea |
N-(4-(.beta.-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N-cyclohexylurea |
172964-66-8 |
N-(2-4-(((Cyclohexylamino)carbonylamino)sulfonyl)phenylethyl)-5-methyl-2-pyrazinecarboxamide |
N-2-(4-{(cyclohexylamino)carbonylaminosulfonyl}phenyl)ethyl(5-methylpyrazi n-2-yl)carboxamide |
Experimental Data
glipizide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 10 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
glipizide
Statistics Data
glipizide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10 | 1 | 1 |
Statistics Data Visualization
glipizide
