Compound Summary
Compound Information
furosemide
Compound Name: | furosemide |
Compound CID: | 3440 |
Synonyms: | furosemide 54-31-9 Frusemide Lasix Furosemid More... |
Iupac Name: | 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid |
InChI: | InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19) |
InChIKey: | ZZUFCTLCJUWOSV-UHFFFAOYSA-N |
Canonical Smiles: | C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl |
Isomeric Smiles: | C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl |
Molecular Weight: | 330.74 |
Molecular Formula: | C12H11ClN2O5S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
furosemide
Molecular Weight: | 330.74 |
Molecular Formula: | C12H11ClN2O5S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 21 |
Complexity: | 481 |
Synonyms
furosemide
| furosemide | furosemide |
|---|---|
furosemide |
54-31-9 |
Frusemide |
Lasix |
Furosemid |
Furanthril |
Errolon |
Fusid |
Aisemide |
Beronald |
Desdemin |
Frusemin |
Fuluvamide |
Furanthryl |
Furantril |
Fursemide |
Lowpstron |
Macasirool |
Prefemin |
Rosemide |
Trofurit |
Fulsix |
Furesis |
Katlex |
Lasilix |
Radonna |
Seguril |
Transit |
Lasex |
Salix |
Urex |
Eutensin |
Frusetic |
Fursemid |
Promedes |
Frusid |
Lazix |
Frusemid |
Frusenex |
Furanturil |
Furosedon |
Profemin |
Urosemide |
Aluzine |
Diural |
Dryptal |
Impugan |
Nicorol |
Rusyde |
Uremide |
Uresix |
Yidoli |
Disal |
Laxur |
Urian |
Apo-Frusemide |
Hydro-rapid |
Anfuramaide |
Arasemide |
Bioretic |
Disemide |
Diurapid |
Diurolasa |
Diusemide |
Durafurid |
Fluidrol |
Frusedan |
Fuluvamine |
Furobeta |
Furodiurol |
Furodrix |
Furorese |
Furosemix |
Furoside |
Furosifar |
Furovite |
Fursemida |
Hissuflux |
Hydroled |
Jenafusid |
Lasiletten |
Logirene |
Lowpston |
Marsemide |
Moilarorin |
Novosemide |
Protargen |
Radisemide |
Selectofur |
Sigasalur |
Spirofur |
Synephron |
Zafimida |
Aldalix |
Aquarid |
Aquasin |
Cetasix |
Dirine |
Discoid |
Diurin |
Diusil |
Diuzol |
Dranex |
Edemid |
Edenol |
Endural |
Farsix |
Franyl |
Frumex |
Frumide |
Frusema |
Furetic |
Furfan |
Furmid |
Furocot |
Furomen |
Furomex |
Furosan |
Furose |
Furosix |
Furoter |
Fursol |
Hydrex |
Kofuzon |
Kolkin |
Kutrix |
Lasemid |
Liside |
Luscek |
Mirfat |
Nelsix |
Odemase |
Odemex |
Oedemex |
Promide |
Puresis |
Radouna |
Salinex |
Salurex |
Salurid |
Uridon |
Uritol |
Aldic |
Depix |
Desal |
Eliur |
Fluss |
Furex |
Furix |
Golan |
Hydro |
Nadis |
Retep |
Rosis |
Vesix |
Mita |
Apo-Furosemide |
Furo-puren |
Lasix Retard |
Polysquall A |
less Diur |
Neo-renal |
Furo-Basan |
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid |
Furosemidu |
Furosemidum |
Urex-M |
Nephron |
Furomide M.D. |
Furosemida |
Osyrol |
4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid |
LB 502 |
5-(Aminosulfonyl)-4-chloro-2-(2-furylmethyl)aminobenzoic acid |
2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid |
NCI-C55936 |
C12H11ClN2O5S |
Lasix (TN) |
Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-(2-furanylmethyl)amino- |
4-chloro-2-(furan-2-ylmethyl)amino-5-sulfamoylbenzoic acid |
Diumide-K |
LB-502 |
4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid |
4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid |
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure |
UNII-7LXU5N7ZO5 |
Anthranilic acid, 4-chloro-N-furfuryl-5-sulfamoyl- |
CHEMBL35 |
4-Chloro-2-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid |
Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)- |
7LXU5N7ZO5 |
CHEBI:47426 |
106391-48-4 |
Furosemidu Polish |
5-(Aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid |
5-(Aminosulfonyl)-4-chloro-2-(2-furanylmethyl)aminobenzoic acid |
MFCD00010549 |
NSC-269420 |
CAS-54-31-9 |
Furosemidum INN-Latin |
Furosemida INN-Spanish |
NCGC00016241-06 |
4-chloro-2-(2-furylmethyl)amino-5-sulfamoylbenzoic acid |
Sal diureticum |
4-chloro-2-{(furan-2-yl)methylamino}-5-sulfamoylbenzoic acid |
DSSTox_CID_648 |
DSSTox_RID_75710 |
DSSTox_GSID_20648 |
Furosemide "mita" |
FUN |
Furosemide mita |
Furosemide oral |
4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID pound>>Furosemide |
5-(Aminosulfonyl)-4-chloro-2-(2-furanylmethylamino)benzoic acid |
5-(aminosulfonyl)-4-chloro-2-(furan-2-ylmethyl)aminobenzoic acid |
SMR000058202 |
CCRIS 1951 |
furosemide mita |
HSDB 3086 |
SR-01000765380 |
EINECS 200-203-6 |
Hoe-058A |
NSC 269420 |
BRN 0840915 |
Neosemid |
Zafurida |
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure German |
Furosemide, 4 |
Urex M |
furosemide (lasix) |
Prestwick_752 |
Frumil (Salt/Mix) |
Furosemide USAN:USP:INN:BAN:JAN |
Spectrum_001100 |
1z9y |
Prestwick0_000341 |
Prestwick1_000341 |
Prestwick2_000341 |
Prestwick3_000341 |
Spectrum2_001005 |
Spectrum3_000437 |
Spectrum4_000560 |
Spectrum5_000744 |
F0182 |
ACMC-20e7w6 |
UPCMLD-DP022 |
SCHEMBL9811 |
Oprea1_667724 |
BSPBio_000401 |
BSPBio_002054 |
KBioGR_001259 |
KBioSS_001580 |
5-18-09-00555 (Beilstein Handbook Reference) |
MLS001066374 |
MLS001306403 |
MLS002548896 |
ARONIS24304 |
BIDD:GT0139 |
DivK1c_000575 |
SPECTRUM1500310 |
SPBio_001129 |
SPBio_002322 |
BPBio1_000443 |
Furosemide (JP17/USP/INN) |
GTPL4839 |
DTXSID6020648 |
UPCMLD-DP022:001 |
BDBM25902 |
HMS501M17 |
KBio1_000575 |
KBio2_001580 |
KBio2_004148 |
KBio2_006716 |
KBio3_001274 |
ZINC35804 |
4-chloro-2-(2-furylmethylamino)-5-sulfamoyl-benzoic acid |
NINDS_000575 |
HMS1569E03 |
HMS1920B03 |
HMS2090K06 |
HMS2091H05 |
HMS2096E03 |
HMS2233H03 |
HMS3259M03 |
HMS3370J22 |
HMS3655E09 |
HMS3713E03 |
HMS3874G03 |
Pharmakon1600-01500310 |
Furosemide 1.0 mg/ml in Methanol |
ALBB-019200 |
HY-B0135 |
Tox21_110322 |
Tox21_202213 |
Tox21_302971 |
BBL027780 |
CCG-40223 |
NSC269420 |
NSC757039 |
SBB012613 |
STK177334 |
WLN: T5OJ B1MR CG FVQ DSZW |
AKOS000266625 |
Tox21_110322_1 |
BCP9000708 |
CS-1915 |
DB00695 |
KS-1226 |
MCULE-8037874224 |
NC00453 |
NSC-757039 |
IDI1_000575 |
SMP1_000129 |
NCGC00016241-01 |
NCGC00016241-02 |
NCGC00016241-03 |
NCGC00016241-04 |
NCGC00016241-05 |
NCGC00016241-07 |
NCGC00016241-08 |
NCGC00016241-10 |
NCGC00016241-11 |
NCGC00090893-01 |
NCGC00090893-02 |
NCGC00090893-03 |
NCGC00090893-05 |
NCGC00090893-06 |
NCGC00256523-01 |
NCGC00259762-01 |
AC-11067 |
BF166384 |
BP-13261 |
H788 |
ST005581 |
SBI-0051389.P003 |
AB0007947 |
DB-052536 |
AB00052001 |
SW196894-3 |
54F319 |
C07017 |
D00331 |
D87719 |
J10011 |
AB00052001-10 |
AB00052001-11 |
AB00052001_12 |
AB00052001_13 |
A830094 |
Q388801 |
SR-01000765380-2 |
SR-01000765380-3 |
SR-01000765380-7 |
BRD-K78010432-001-05-8 |
BRD-K78010432-001-10-8 |
Z275128584 |
4-chloro-2-(2-furanylmethylamino)-5-sulfamoylbenzoic acid |
Furosemide, British Pharmacopoeia (BP) Reference Standard |
Furosemide, European Pharmacopoeia (EP) Reference Standard |
4-chloranyl-2-(furan-2-ylmethylamino)-5-sulfamoyl-benzoic acid |
Furosemide, United States Pharmacopeia (USP) Reference Standard |
4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID Furosemide |
5-(Aminosulfamyl)-4-chloro-2-(2-furanylmethyl)aminobenzoic acid |
5-(Aminosulfonyl)-4-chloro-2-(2-furylmethyl)aminobenzoic acid # |
Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material |
Furosemide for peak identification, European Pharmacopoeia (EP) Reference Standard |
Furosemide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
Experimental Data
furosemide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | umol/L | 49.36 | 47.5 | -3.758 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 17.95 | 16.72 | -6.876 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33 | umol/L | -2 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 100 | umol/L | 17.14 | 15.88 | -7.347 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 45.82 | 43.3 | -5.493 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
furosemide
Statistics Data
furosemide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2 | 2 | 3 | |
| Drosophila melanogaster | -3.758 | 1 | 2 |
Statistics Data Visualization
furosemide
