Compound Summary
Compound Information
5-Fluorouracil
Compound Name: | 5-Fluorouracil |
Compound CID: | 3385 |
Synonyms: | 5-Fluorouracil fluorouracil 51-21-8 5-FU Fluoroplex More... |
Iupac Name: | 5-fluoro-1H-pyrimidine-2,4-dione |
InChI: | InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
InChIKey: | GHASVSINZRGABV-UHFFFAOYSA-N |
Canonical Smiles: | C1=C(C(=O)NC(=O)N1)F |
Isomeric Smiles: | C1=C(C(=O)NC(=O)N1)F |
Molecular Weight: | 130.08 |
Molecular Formula: | C4H3FN2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
5-Fluorouracil
Molecular Weight: | 130.08 |
Molecular Formula: | C4H3FN2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 9 |
Complexity: | 199 |
Synonyms
5-Fluorouracil
| 5-Fluorouracil | 5-Fluorouracil |
|---|---|
5-Fluorouracil |
fluorouracil |
51-21-8 |
5-FU |
Fluoroplex |
Efudex |
Adrucil |
Carac |
Fluracil |
5-fluoropyrimidine-2,4(1H,3H)-dione |
Fluoroblastin |
Kecimeton |
Carzonal |
Timazin |
Arumel |
Efudix |
Fluril |
5-Fluoracil |
Fluracilum |
Queroplex |
Ulup |
Phthoruracil |
Fluro Uracil |
5-fluoro-1H-pyrimidine-2,4-dione |
Fluorouracilum |
Ftoruracil |
Efurix |
Fluri |
5-Fluoro-2,4(1H,3H)-pyrimidinedione |
5 Fluorouracil |
5-Fluoropyrimidine-2,4-dione |
Effluderm (free base) |
Fluorouracilo |
2,4(1H,3H)-Pyrimidinedione, 5-fluoro- |
2,4-Dihydroxy-5-fluoropyrimidine |
5-fluoropyrimidine-2,4-diol |
Uracil, 5-fluoro- |
5-Fluoruracil |
Ro 2-9757 |
5-Fluor-2,4-pyrimidindiol |
5-fluoro uracil |
5-Ftouracyl |
NSC 19893 |
Fluorouracil, 5- |
NSC-19893 |
5-Fluoro-2,4-pyrimidinedione |
Fluorouracil (Adrucil) |
5-Fluor-2,4-dihydroxypyrimidin |
U-8953 |
5-fluoro-uracil |
Ro-2-9757 |
UNII-U3P01618RT |
191047-65-1 |
FU |
CHEMBL185 |
2,4-Pyrimidinediol, 5-fluoro- (9CI) |
MLS000069498 |
5FU |
Fluroblastin |
Phtoruracil |
CHEBI:46345 |
Fluoro-uracile |
Fluoro-uracilo |
U3P01618RT |
NSC19893 |
2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI) |
4(3H)-Pyrimidinone, 5-fluoro-2-hydroxy- (9CI) |
5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione |
5-Faracil |
Cinco FU |
MFCD00006018 |
191047-64-0 |
191115-88-5 |
URF |
NCGC00015442-02 |
Fluorouracile |
Effluderm |
SMR000038082 |
DSSTox_CID_634 |
Fluorouracile DCIT |
5-Fluoracil German |
5-Fluoracyl |
5-Fluoruracil German |
DSSTox_RID_75705 |
DSSTox_GSID_20634 |
Fluorouracilum INN-Latin |
Fluorouracilo INN-Spanish |
5-Fluoropyrimidin-2,4-diol |
2,4-Dioxo-5-fluoropyrimidine |
Fluorouracil Cream |
CAS-51-21-8 |
Fluoroplex (TN) |
5-Fluor-2,4-pyrimidindiol Czech |
Adrucil (TN) |
5-fluoro-1,3-dihydropyrimidine-2,4-dione |
CCRIS 2582 |
Carac (TN) |
5-Fluor-2,4-dihydroxypyrimidin Czech |
HSDB 3228 |
SR-01000075881 |
5-Fluor-2,4(1H,3H)-pyrimidindion Czech |
EINECS 200-085-6 |
5-Fluor-2,4(1H,3H)-pyrimidindion |
Fluouracil |
inhibits thymilidate synthetase |
Tolak |
2,4-Dioxo-5-fluoropryimidine |
5-fluorourasil |
AI3-25297 |
Fluoro Uracil |
5-florouracil |
5-fluorouacil |
5-FU (TN) |
5-Fluracil |
1upf |
5F-uracil |
U 8953 |
1-fluoro-1h-pyrimidine-2,4-dione |
Adrucil (ICN) |
Adrucil (Fluorouracil) |
Fluorouracil - Adrucil |
Fluorouracil USAN:USP:INN:BAN:JAN |
Spectrum_000841 |
ACMC-1ATRK |
Opera_ID_134 |
5-Fluorouracil, 99% |
Spectrum2_000076 |
Spectrum3_000434 |
Spectrum4_000557 |
Spectrum5_000718 |
WLN: T6MVMVJ EF |
Lopac-F-6627 |
F0151 |
UPCMLD-DP130 |
EC 200-085-6 |
F 6627 |
SCHEMBL3646 |
5-fluorpyrimidin-2,4-diol |
Lopac0_000536 |
BSPBio_002048 |
KBioGR_001253 |
KBioSS_001321 |
MLS002415705 |
5-fluoro-2,4-Pyrimidinediol |
DivK1c_000054 |
SPECTRUM1500305 |
SPBio_000291 |
5 FU |
5-fluoro-2,4-dioxo-pyrimidin |
5-fluoro-pyrimidine-2,4-diol |
GTPL4789 |
DTXSID2020634 |
UPCMLD-DP130:001 |
Fluorouracil (JP17/USP/INN) |
HMS500C16 |
KBio1_000054 |
KBio2_001321 |
KBio2_003889 |
KBio2_006457 |
KBio3_001268 |
5-Fluoro-2,3H)-pyrimidinedione |
2,4-Pyrimidinedione, 5-fluoro- |
NINDS_000054 |
BCPP000428 |
HMS1920O18 |
HMS2090I04 |
HMS2091F19 |
HMS3259O03 |
HMS3261L13 |
HMS3654K22 |
HMS3715H03 |
HMS3865L03 |
Pharmakon1600-01500305 |
5-Fluorouracil, analytical standard |
BCP02083 |
2,3H)-Pyrimidinedione, 5-fluoro- |
Fluorouracil (5-Fluoracil, 5-FU) |
Fluorouracil (5-Fluoracil; 5-FU) |
Tox21_110150 |
Tox21_202335 |
Tox21_300112 |
Tox21_500536 |
BBL009635 |
BDBM50340677 |
CCG-39879 |
CF0033 |
DL-399 |
NSC757036 |
Ro-29757 |
s1209 |
SBB085751 |
STK297802 |
STL367375 |
ZINC38212689 |
AKOS000119162 |
AKOS003237897 |
AKOS008044307 |
Tox21_110150_1 |
BCP9000239 |
CS-0993 |
DB00544 |
KS-5129 |
LP00536 |
LS40596 |
MCULE-6338086431 |
NC00454 |
NSC-757036 |
SDCCGSBI-0050519.P005 |
IDI1_000054 |
NCGC00015442-01 |
NCGC00015442-03 |
NCGC00015442-04 |
NCGC00015442-05 |
NCGC00015442-06 |
NCGC00015442-07 |
NCGC00015442-08 |
NCGC00015442-09 |
NCGC00015442-10 |
NCGC00015442-11 |
NCGC00015442-12 |
NCGC00015442-15 |
NCGC00015442-16 |
NCGC00015442-24 |
NCGC00015442-30 |
NCGC00091349-01 |
NCGC00091349-02 |
NCGC00091349-03 |
NCGC00091349-04 |
NCGC00091349-05 |
NCGC00091349-07 |
NCGC00091349-08 |
NCGC00254023-01 |
NCGC00259884-01 |
NCGC00261221-01 |
1004-03-1 |
5-Fluoro-2,4-(1H,3H)-pyrimidinedione |
AC-11201 |
BF166014 |
HY-90006 |
NCI60_001652 |
SRI-10792-04 |
SRI-10792-05 |
SRI-10792-06 |
SRI-10792_07 |
SRI-10792_08 |
5-Fluoro-1H-pyrimidine-2,4-dione(5FU) |
5-Fluorouracil, >=99% (HPLC), powder |
SBI-0050519.P004 |
5-Fluoro-1H-pyrimidine-2,4-dione(5-FU) |
DB-051923 |
DB-065735 |
5-Fluoro-1H-pyrimidine-2,4-dione (5-FU) |
AM20100252 |
EU-0100536 |
FT-0601511 |
FT-0668745 |
FT-0695666 |
FT-0695667 |
FT-0707652 |
ST45025877 |
SW199617-3 |
5-Fluoro-1H-pyrimidine-2,4-dione(5-FUra) |
Fluorouracil, meets USP testing specifications |
51F218 |
7375-EP2269989A1 |
7375-EP2269994A1 |
7375-EP2270008A1 |
7375-EP2270018A1 |
7375-EP2272827A1 |
7375-EP2272832A1 |
7375-EP2275102A1 |
7375-EP2275412A1 |
7375-EP2275413A1 |
7375-EP2277876A1 |
7375-EP2280012A2 |
7375-EP2281563A1 |
7375-EP2281815A1 |
7375-EP2287156A1 |
7375-EP2289892A1 |
7375-EP2292233A2 |
7375-EP2292614A1 |
7375-EP2292615A1 |
7375-EP2292617A1 |
7375-EP2295416A2 |
7375-EP2295426A1 |
7375-EP2295427A1 |
7375-EP2298748A2 |
7375-EP2298768A1 |
7375-EP2298772A1 |
7375-EP2298780A1 |
7375-EP2301928A1 |
7375-EP2301933A1 |
7375-EP2305219A1 |
7375-EP2305243A1 |
7375-EP2305640A2 |
7375-EP2305642A2 |
7375-EP2305671A1 |
7375-EP2305689A1 |
7375-EP2308833A2 |
7375-EP2308839A1 |
7375-EP2308855A1 |
7375-EP2308861A1 |
7375-EP2311807A1 |
7375-EP2311808A1 |
7375-EP2311825A1 |
7375-EP2311827A1 |
7375-EP2311829A1 |
7375-EP2311840A1 |
7375-EP2314590A1 |
7375-EP2316459A1 |
7375-EP2316831A1 |
7375-EP2316834A1 |
7375-EP2316974A1 |
7375-EP2374454A1 |
C07649 |
D00584 |
29507-EP2270008A1 |
29507-EP2270505A1 |
29507-EP2272827A1 |
29507-EP2289892A1 |
29507-EP2292234A1 |
29507-EP2292617A1 |
29507-EP2295426A1 |
29507-EP2295427A1 |
29507-EP2298305A1 |
29507-EP2308861A1 |
29507-EP2311842A2 |
42164-EP2272827A1 |
42164-EP2275420A1 |
42164-EP2277565A2 |
42164-EP2277566A2 |
42164-EP2277567A1 |
42164-EP2277568A2 |
42164-EP2277569A2 |
42164-EP2277570A2 |
42164-EP2277876A1 |
42164-EP2292280A1 |
42164-EP2292614A1 |
42164-EP2295412A1 |
42164-EP2295413A1 |
42164-EP2295416A2 |
42164-EP2298748A2 |
42164-EP2298764A1 |
42164-EP2298765A1 |
42164-EP2298778A1 |
42164-EP2305642A2 |
42164-EP2308833A2 |
42164-EP2311808A1 |
42164-EP2311829A1 |
42164-EP2311840A1 |
5-Fluorouracil, Vetec(TM) reagent grade, >=99% |
Q238512 |
W-60379 |
(5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |
5-Fluoro-1H-pyrimidine-2,4-dione(5-fluoro uracil) |
SR-01000075881-1 |
SR-01000075881-3 |
SR-01000075881-5 |
W-202929 |
5-Fluoro-1H-pyrimidine-2,4-dione (5-Fluorouracil) |
BRD-K24844714-001-02-1 |
Z275128052 |
5-Fluoro-1H-pyrimidine-2,4-dione(5-fluorouracil)(5-FU) |
5-Fluorouracil, certified reference material, TraceCERT(R) |
Fluorouracil, British Pharmacopoeia (BP) Reference Standard |
Fluorouracil, European Pharmacopoeia (EP) Reference Standard |
Fluorouracil, United States Pharmacopeia (USP) Reference Standard |
pyrimidine antimetabolite: inhibits nucleic acid replication; tetratogen |
Fluorouracil, Pharmaceutical Secondary Standard; Certified Reference Material |
Experimental Data
5-Fluorouracil
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
5-Fluorouracil
Statistics Data
5-Fluorouracil
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5 | 1 | 1 |
Statistics Data Visualization
5-Fluorouracil
