Compound Summary
Compound Information
flumazenil
Compound Name: | flumazenil |
Compound CID: | 3373 |
Synonyms: | flumazenil 78755-81-4 Anexate Flumazepil Romazicon More... |
Iupac Name: | ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate |
InChI: | InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3 |
InChIKey: | OFBIFZUFASYYRE-UHFFFAOYSA-N |
Canonical Smiles: | CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C |
Isomeric Smiles: | CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C |
Molecular Weight: | 303.29 |
Molecular Formula: | C15H14FN3O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
flumazenil
Molecular Weight: | 303.29 |
Molecular Formula: | C15H14FN3O3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 22 |
Complexity: | 461 |
Synonyms
flumazenil
| flumazenil | flumazenil |
|---|---|
flumazenil |
78755-81-4 |
Anexate |
Flumazepil |
Romazicon |
Lanexat |
Mazicon |
Ro 15-1788 |
fumazenil |
Flumazenilum Latin |
Flumazenilo Spanish |
Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzofimidazo1,5-a1,4diazepine-3-carboxylate |
Flumazenilo |
Flumazenilum |
11Cflumazenil |
Ro-15-1788 |
Ro 151788 |
Flumazenil (Ro 15-1788) |
ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate |
UNII-40P7XK9392 |
Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate |
CHEMBL407 |
Ro15-1788 |
MLS000028850 |
CHEBI:5103 |
ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo8.4.0.0^{2,6}tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate |
MFCD00242764 |
40P7XK9392 |
4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester |
NCGC00015439-06 |
SMR000058450 |
RO-151788 |
DSSTox_CID_3064 |
Ro 15-1788/000 |
DSSTox_RID_76860 |
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate |
DSSTox_GSID_23064 |
Flumazil |
3HRo15-1788 |
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate |
CAS-78755-81-4 |
SR-01000075879 |
BRN 4763661 |
Flumenazil |
Flunarizin |
Roma |
11Cflumazenil (PET ligand) |
Flumazenil USAN:USP:INN:BAN |
Romazicon (TN) |
Flumazenil authentic |
FYP |
Flumazenil- Bio-X |
Tocris-1328 |
Opera_ID_1516 |
Lopac-F-6300 |
Biomol-NT_000285 |
UPCMLD-DP137 |
Ethyl 8-fluoro-5-methyl-5,6-dihydro-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate |
Lopac0_000506 |
SCHEMBL79030 |
Flumazenil (JAN/USP/INN) |
MLS000759529 |
MLS001076354 |
MLS001424108 |
BIDD:GT0766 |
BPBio1_001190 |
GTPL4192 |
GTPL4367 |
ZINC1464 |
DTXSID2023064 |
UPCMLD-DP137:001 |
BDBM26263 |
AOB5595 |
HMS2051D17 |
HMS2089B15 |
HMS2234F06 |
HMS3261F13 |
HMS3267P09 |
HMS3374E10 |
HMS3393D17 |
HMS3412G20 |
HMS3657K11 |
HMS3676G20 |
HMS3884G11 |
Pharmakon1600-01505701 |
AFC-3002 |
AMY39505 |
BCP07573 |
HY-B0009 |
Flumazenil, >99% (HPLC), solid |
Tox21_110148 |
Tox21_500506 |
NSC759193 |
PDSP1_001778 |
PDSP2_001761 |
s1332 |
AKOS015888159 |
Tox21_110148_1 |
AC-6846 |
CCG-100968 |
CS-0629 |
DB01205 |
LP00506 |
MCULE-2830706565 |
NC00218 |
NSC 759193 |
NSC-759193 |
RO-1722 |
SDCCGSBI-0050490.P003 |
NCGC00015439-01 |
NCGC00015439-02 |
NCGC00015439-03 |
NCGC00015439-04 |
NCGC00015439-05 |
NCGC00015439-07 |
NCGC00015439-08 |
NCGC00015439-09 |
NCGC00015439-11 |
NCGC00015439-14 |
NCGC00015439-22 |
NCGC00025116-01 |
NCGC00025116-02 |
NCGC00025116-03 |
NCGC00025116-04 |
NCGC00025116-05 |
NCGC00261191-01 |
AS-13923 |
BF164469 |
Flumazenil 100 microg/mL in Acetonitrile |
K393 |
SBI-0050490.P002 |
AB0014201 |
DB-056331 |
Ro-151788000 |
EU-0100506 |
F-145 |
F0958 |
FT-0630863 |
RO-41-8157 |
SW197598-2 |
Ro-15-1788/000 |
C07825 |
D00697 |
F 6300 |
AB00572626-12 |
AB00572626-13 |
AB00572626_14 |
AB00572626_15 |
755F814 |
A839484 |
Q421920 |
Q-201122 |
SR-01000075879-1 |
SR-01000075879-3 |
SR-01000075879-7 |
BRD-K98769987-001-01-3 |
BRD-K98769987-001-12-0 |
Z1551429735 |
Flumazenil, United States Pharmacopeia (USP) Reference Standard |
ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate. |
4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-,ethyl ester |
4H-Imidazo1,5-a1,4benzodiazepine-3-carboxylic acid, 8- fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester |
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylic acid ethyl ester |
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylic acid, ethyl ester |
8-fluoro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylic acid ethyl ester |
ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo8.4.0.0^{2,6}tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate |
ethyl 8-fluoranyl-5-methyl-6-oxidanylidene-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate |
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a 1,4benzodiazepine-3-carboxylate |
ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a1,4-benzodiazepine-3-carboxylate |
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo1,5-a1,4benzodiazepin-3-carboxylate |
Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo1,5-a1,4benzodiazepine-3-carboxylate # |
Experimental Data
flumazenil
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
flumazenil
Statistics Data
flumazenil
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 6 | 1 | 1 |
Statistics Data Visualization
flumazenil
