Compound Summary
Compound Information
fenofibrate
Compound Name: | fenofibrate |
Compound CID: | 3339 |
Synonyms: | fenofibrate 49562-28-9 Procetofen Lipantil Tricor More... |
Iupac Name: | propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate |
InChI: | InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3 |
InChIKey: | YMTINGFKWWXKFG-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl |
Isomeric Smiles: | CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl |
Molecular Weight: | 360.8 |
Molecular Formula: | C20H21ClO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
fenofibrate
Molecular Weight: | 360.8 |
Molecular Formula: | C20H21ClO4 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 25 |
Complexity: | 458 |
Synonyms
fenofibrate
| fenofibrate | fenofibrate |
|---|---|
fenofibrate |
49562-28-9 |
Procetofen |
Lipantil |
Tricor |
Lipanthyl |
Fenobrate |
Lipidil |
Secalip |
Antara |
Finofibrate |
Lipoclar |
Lipofene |
Proctofene |
Triglide |
Fenogal |
Lipirex |
Sedufen |
Elasterin |
Fenoglide |
Fenotard |
Protolipan |
Ankebin |
Lipidex |
Lipifen |
Lipofen |
Liposit |
Lipsin |
Nolipax |
Fenofibratum INN-Latin |
propan-2-yl 2-4-(4-chlorobenzoyl)phenoxy-2-methylpropanoate |
Fenofibrato INN-Spanish |
Lipantil (TN) |
Tricor (TN) |
LF-178 |
C20H21ClO4 |
Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate |
Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate |
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester |
NSC 281319 |
UNII-U202363UOS |
Isopropyl (4-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate |
FNF |
Elasterate |
Procetofene |
Luxacor |
CHEMBL672 |
Propanoic acid, 2-4-(4-chlorobenzoyl)phenoxy-2-methyl-, 1-methylethyl ester |
MLS000028515 |
CHEBI:5001 |
isopropyl 2-4-(4-chlorobenzoyl)phenoxy-2-methylpropanoate |
Lofibra |
U202363UOS |
Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester |
MFCD00133314 |
NSC-281319 |
NCGC00015437-10 |
Fenofibrato |
Fenofibratum |
Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate |
SMR000058299 |
Supralip |
CAS-49562-28-9 |
DSSTox_CID_9874 |
propan-2-yl 2-{4-(4-chlorophenyl)carbonylphenoxy}-2-methylpropanoate |
DSSTox_RID_78828 |
DSSTox_GSID_29874 |
TRICOR (MICRONIZED) |
Antara (micronized) |
Fenomax |
Isopropyl 2-p-(p-chlorobenzoyl)phenoxy-2-methylpropionate |
Pharmavit |
FENOFIBRATE (MICRONIZED) |
Fulcro |
2-4-(4-Chlorobenzoyl)phenoxy-2-methylpropanoic acid isopropyl ester |
2-4-(4-Chlorobenzoyl)phenoxy-2-methylpropionic Acid Isopropyl Ester |
CIP-Fenofibrate |
2-4-(4-Chlorobenzoyl)phenoxy-2-methylpropanoic acid 1-methylethyl ester |
LCP-FenoChol |
LCP-Feno |
Triglide (TN) |
Fenofibrate IDD-P |
Lipofen (TN) |
Antara (TN) |
CCRIS 7282 |
SR-01000000091 |
EINECS 256-376-3 |
LF 178 |
BRN 2062462 |
Procetoken |
Isopropyl 2-4-(4-Chlorobenzoyl)phenoxy-2-methylpropionate |
fenofibrate; |
methylethyl 2-{4-(4-chlorophenyl)carbonylphenoxy}-2-methylpropanoate |
HSDB 7736 |
Fenofibrate,(S) |
GRS-027 |
Fenofibrate USAN:USP:INN:BAN |
Prestwick_217 |
Spectrum_001250 |
Opera_ID_328 |
Prestwick0_000275 |
Prestwick1_000275 |
Prestwick2_000275 |
Prestwick3_000275 |
Spectrum2_001390 |
Spectrum3_001431 |
Spectrum4_000413 |
Spectrum5_001479 |
Lopac-F-6020 |
EC 256-376-3 |
F 6020 |
SCHEMBL4670 |
Lopac0_000486 |
BSPBio_000150 |
BSPBio_003162 |
KBioGR_000706 |
KBioSS_001730 |
MLS001148191 |
MLS002548878 |
BIDD:GT0574 |
DivK1c_000557 |
Fenofibrate (JAN/USP/INN) |
SPECTRUM1501010 |
SPBio_001380 |
SPBio_002369 |
Fenofibrate, >=99%, powder |
BPBio1_000166 |
Fenofibrate (Tricor, Trilipix) |
GTPL7186 |
DTXSID2029874 |
HMS501L19 |
KBio1_000557 |
KBio2_001730 |
KBio2_004298 |
KBio2_006866 |
KBio3_002382 |
NINDS_000557 |
HMS1568H12 |
HMS1921B17 |
HMS2090G20 |
HMS2092B05 |
HMS2095H12 |
HMS2231B14 |
HMS3259K03 |
HMS3261B13 |
HMS3369M13 |
HMS3649D20 |
HMS3655K12 |
HMS3712H12 |
isopropyl 2-4-(4-chlorobenzoyl)phenoxy-2-methyl-propanoate |
Pharmakon1600-01501010 |
ZINC584092 |
ALBB-028958 |
BCP21243 |
EBD45918 |
Tox21_110147 |
Tox21_300151 |
Tox21_500486 |
BDBM50085042 |
CCG-38996 |
NSC281319 |
NSC757822 |
s1794 |
SBB037926 |
AKOS005107777 |
Propanoic acid, 2-4-(4-chlorobenzoyl)phenoxy-2-methyl-, 1-methylethylester |
Tox21_110147_1 |
AB03716 |
AC-4227 |
CS-0892 |
DB01039 |
LP00486 |
MCULE-9460650238 |
MS-2223 |
NC00452 |
NSC-757822 |
SDCCGSBI-0050470.P004 |
IDI1_000557 |
NCGC00015437-01 |
NCGC00015437-02 |
NCGC00015437-03 |
NCGC00015437-04 |
NCGC00015437-05 |
NCGC00015437-06 |
NCGC00015437-07 |
NCGC00015437-08 |
NCGC00015437-09 |
NCGC00015437-11 |
NCGC00015437-12 |
NCGC00015437-13 |
NCGC00015437-14 |
NCGC00015437-16 |
NCGC00015437-17 |
NCGC00015437-31 |
NCGC00021475-03 |
NCGC00021475-04 |
NCGC00021475-05 |
NCGC00021475-06 |
NCGC00021475-07 |
NCGC00021475-08 |
NCGC00253945-01 |
NCGC00261171-01 |
FENOFIBRATE (MICRONIZED) (fenofibrate |
Fenofibrate, analytical reference material |
HY-17356 |
ST085313 |
SBI-0050470.P003 |
AB0012237 |
DB-051642 |
AB00052196 |
EU-0100486 |
F0674 |
FT-0626400 |
FT-0654669 |
SW196525-4 |
C07586 |
D00565 |
J10318 |
28073-EP2272825A2 |
28073-EP2272841A1 |
28073-EP2277565A2 |
28073-EP2277566A2 |
28073-EP2277567A1 |
28073-EP2277568A2 |
28073-EP2277569A2 |
28073-EP2277570A2 |
28073-EP2287163A1 |
28073-EP2287165A2 |
28073-EP2287166A2 |
28073-EP2292280A1 |
28073-EP2292620A2 |
28073-EP2295409A1 |
28073-EP2298742A1 |
28073-EP2298776A1 |
28073-EP2301923A1 |
28073-EP2301936A1 |
28073-EP2305678A1 |
28073-EP2314588A1 |
AB00052196-15 |
AB00052196-16 |
AB00052196_17 |
AB00052196_18 |
562F289 |
A827746 |
Q419724 |
Q-201111 |
SR-01000000091-2 |
SR-01000000091-5 |
SR-01000000091-6 |
SR-01000000091-8 |
BRD-K50388907-001-05-6 |
BRD-K50388907-001-18-9 |
BRD-K50388907-001-20-5 |
SR-01000000091-16 |
Z2768724415 |
Fenofibrate, European Pharmacopoeia (EP) Reference Standard |
Isopropyl 2-(4-(4-chlorobenzoyl)-phenoxy)-2-methylpropanoate |
1-methylethyl 2-4-(4-chlorobenzoyl)phenoxy-2-methylpropanoate |
2-4-(4-chlorobenzoyl)phenoxy-2-methylpropanoicacidisopropylester |
Fenofibrate, United States Pharmacopeia (USP) Reference Standard |
Isopropyl (4-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate |
2-4-(4-chlorobenzoyl)phenoxy-2-methyl-propanoic acid,1-methylethylester |
2-4-(4-Chlorobenzoyl)phenoxy-2-methylpropanoic acid 1-methyl-ethyl ester |
Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material |
isopropyl 2-4-(4-chlorobenzoyl)phenoxy-2-methyl-propanoate;Fenofibrate |
Experimental Data
fenofibrate
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -6 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 10 | umol/L | 21.6 | 25.6 | 0.19 | 28.1 | 32.8 | 0.17 | S | N2 | 23603800 | Active | |
| Caenorhabditis elegans | 0.1 | umol/L | 21.6 | 22.5 | 0.04 | 28.1 | 34.6 | 0.23 | S | N2 | 23603800 | Active | |
| Caenorhabditis elegans | 1 | umol/L | 21.6 | 22.3 | 0.03 | 28.1 | 28.8 | 0.02 | S | N2 | 23603800 | Active | |
| Caenorhabditis elegans | 10 | umol/L | 21.6 | 23.7 | 0.1 | 28.1 | 30.2 | 0.07 | S | N2 | 23603800 | Active |
Experimental Data Visualization
fenofibrate
Statistics Data
fenofibrate
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.19 | 0.23 | 2 | 5 |
Statistics Data Visualization
fenofibrate
