Compound Summary
Compound Information
SB 204741
Compound Name: | SB 204741 |
Compound CID: | 3277600 |
Synonyms: | SB 204741 152239-46-8 SB204741 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea SB-204741 More... |
Iupac Name: | 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
InChI: | InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) |
InChIKey: | USFUFHFQWXDVMH-UHFFFAOYSA-N |
Canonical Smiles: | CC1=NSC(=C1)NC(=O)NC2=CC3=C(C=C2)N(C=C3)C |
Isomeric Smiles: | CC1=NSC(=C1)NC(=O)NC2=CC3=C(C=C2)N(C=C3)C |
Molecular Weight: | 286.35 |
Molecular Formula: | C14H14N4OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SB 204741
Molecular Weight: | 286.35 |
Molecular Formula: | C14H14N4OS |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 20 |
Complexity: | 367 |
Synonyms
SB 204741
| SB 204741 | SB 204741 |
|---|---|
SB 204741 |
152239-46-8 |
SB204741 |
1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
SB-204741 |
N-(1-methyl-5-indolyl)-N-(3-methyl-5-isothiazolyl)urea |
1-(1-methyl-1H-indol-5-yl)-3-(3-methylisothiazol-5-yl)urea |
MFCD00923644 |
N-(1-METHYL-1H-INDOLYL-5-YL)-N-(3-METHYL-5-ISOTHIAZOLYL)UREA |
C14H14N4OS |
N-(1-Methyl-1H-5-indolyl)-N-(3-methyl-5-isothiazolyl)urea |
1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
SR-01000075765 |
SB-204,741 |
Tocris-1372 |
Lopac-S-0693 |
Lopac0_000255 |
GTPL221 |
MLS000862184 |
CHEMBL323356 |
SCHEMBL3377716 |
BDBM84991 |
ZINC16912 |
DTXSID80390956 |
CHEBI:140936 |
HMS2231C03 |
HMS3260D12 |
HMS3369K08 |
BCP28144 |
CGA23946 |
EX-A4910 |
Tox21_500255 |
PDSP1_001580 |
PDSP2_001564 |
AKOS024456556 |
CCG-204350 |
LP00255 |
SDCCGSBI-0050243.P002 |
CAS_3277600 |
NSC_3277600 |
NCGC00015923-01 |
NCGC00015923-02 |
NCGC00015923-03 |
NCGC00015923-04 |
NCGC00015923-05 |
NCGC00015923-06 |
NCGC00015923-09 |
NCGC00025129-01 |
NCGC00025129-02 |
NCGC00025129-03 |
NCGC00260940-01 |
SMR000326947 |
DB-043133 |
B6708 |
EU-0100255 |
FT-0643481 |
Q44787 |
S 0693 |
SB 204741, >98% (HPLC) |
A809277 |
L000536 |
SB 204741; SB-204741 |
J-008905 |
SR-01000075765-1 |
SR-01000075765-3 |
BRD-K15391446-001-11-0 |
1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea |
N-(1-Methyl-1H-indo-5-yl)-N-(3-methyl-5-isothiazolyl)urea" |
N-(1-Methyl-1H-indolyl-5-yl)-N-(3-m ethyl-5-isothiazolyl)urea" |
N-(1-Methyl-1H-indolyl-5-yl)-N-(3-methyl-5-isothiazolyl) urea |
3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA |
Experimental Data
SB 204741
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -4 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
SB 204741
Statistics Data
SB 204741
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4 | 1 | 1 |
Statistics Data Visualization
SB 204741
