Compound Summary
Compound Information
cyclothiazide
Compound Name: | cyclothiazide |
Compound CID: | 2910 |
Synonyms: | cyclothiazide 2259-96-3 Anhydron Aquirel Renazide More... |
Iupac Name: | 3-(2-bicyclo[2.2.1]hept-5-enyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
InChI: | InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20) |
InChIKey: | BOCUKUHCLICSIY-UHFFFAOYSA-N |
Canonical Smiles: | C1C2CC(C1C=C2)C3NC4=CC(=C(C=C4S(=O)(=O)N3)S(=O)(=O)N)Cl |
Isomeric Smiles: | C1C2CC(C1C=C2)C3NC4=CC(=C(C=C4S(=O)(=O)N3)S(=O)(=O)N)Cl |
Molecular Weight: | 389.9 |
Molecular Formula: | C14H16ClN3O4S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
cyclothiazide
Molecular Weight: | 389.9 |
Molecular Formula: | C14H16ClN3O4S2 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 24 |
Complexity: | 758 |
Synonyms
cyclothiazide
| cyclothiazide | cyclothiazide |
|---|---|
cyclothiazide |
2259-96-3 |
Anhydron |
Aquirel |
Renazide |
Valmiran |
Doburil |
Fluidil |
Ciclotiazide DCIT |
Ciclotiazida |
Cyclothiazidum |
Ciclotiazida INN-Spanish |
Cyclothiazidum INN-Latin |
MDi 193 |
UNII-P71U09G5BW |
6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide |
6-Chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide |
CHEMBL61593 |
P71U09G5BW |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-, 1,1-dioxide |
Ciclotiazide |
CHEBI:31448 |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo(2.2.1)hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo2.2.1hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide |
3-Bicyclo(2.2.1)hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
NCGC00015288-06 |
DSSTox_CID_2871 |
Lilly 35483; MDi 193; Renazide; Valmiran |
DSSTox_RID_76767 |
DSSTox_GSID_22871 |
2H-1,2,4-Benzothiadiazine-7-sulfonamide,3-bicyclo2.2.1hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide |
Lilly 35,483 |
Anhydron (TN) |
3-(bicyclo2.2.1hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-benzoe1,2,4thiadiazine-7-sulfonamide 1,1-dioxide |
3-{bicyclo2.2.1hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide |
3-Bicyclo2.2.1hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide |
CAS-2259-96-3 |
HSDB 3310 |
SR-01000075796 |
EINECS 218-859-7 |
BRN 0722843 |
3-(bicyclo2.2.1hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
Cyclothiazide (JAN/USAN/INN) |
3-(5-bicyclo2.2.1hept-2-enyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide |
Cyclothiazide USAN:USP:INN:BAN |
Disodiumhexafluorozirconate |
Spectrum4_000050 |
Spectrum5_001639 |
Lilly 35483 |
Biomol-NT_000224 |
C 9847 |
6-Chloro-3,4-dihydro-3-(norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
Lopac0_000321 |
KBioGR_000519 |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-chloro-3-(5-norbornen-2-yl)-, 1,1-dioxide |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-chloro-3-(5-norbornen-2-yl)-,1,1-dioxide |
MLS001077326 |
DivK1c_000904 |
SCHEMBL121096 |
BPBio1_001320 |
GTPL4167 |
DTXSID3022871 |
HMS502N06 |
KBio1_000904 |
NINDS_000904 |
Cyclothiazide (mixture of isomers) |
HMS2093A19 |
HMS2236K04 |
HMS3261A03 |
HMS3266L17 |
HMS3373E04 |
HMS3411D03 |
HMS3675D03 |
Pharmakon1600-01503263 |
Tox21_110124 |
Tox21_500321 |
BDBM50192229 |
NSC758431 |
s6611 |
AKOS024458615 |
Tox21_110124_1 |
CCG-204416 |
DB00606 |
LP00321 |
NSC 758431 |
NSC-758431 |
SDCCGSBI-0050309.P004 |
IDI1_000904 |
NCGC00015288-04 |
NCGC00015288-05 |
NCGC00015288-07 |
NCGC00015288-09 |
NCGC00015288-14 |
NCGC00022985-02 |
NCGC00024745-02 |
NCGC00024745-03 |
NCGC00024745-04 |
NCGC00261006-01 |
3-(2-bicyclo2.2.1hept-5-enyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
AS-76539 |
SMR000653479 |
SBI-0050309.P003 |
EU-0100321 |
FT-0665417 |
D01256 |
D81850 |
AB00053281_04 |
J-014778 |
Q5199066 |
SR-01000075796-1 |
SR-01000075796-3 |
SR-01000075796-4 |
BRD-A38675539-001-01-0 |
BRD-A38675539-001-05-1 |
3-Bicyclo2.2.1hept-5-en-2-yl-6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo1,2,4thiadiazine-7-sulfonic acid amide |
3-Bicyclo2.2.1hept-5-en-2-yl-6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo1,2,4thiadiazine-7-sulfonic acid amide(Clothiazide) |
3-Bicyclo2.2.1hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide # |
3-Bicyclo2.2.1hept-5-en-2-yl-7-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo1,2,4thiadiazine-6-sulfonic acid amide |
6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1 ,1-dioxide |
Experimental Data
cyclothiazide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 14 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
cyclothiazide
Statistics Data
cyclothiazide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 14 | 1 | 1 |
Statistics Data Visualization
cyclothiazide
