Compound Summary
Compound Information
danazol
Compound Name: | danazol |
Compound CID: | 28417 |
Synonyms: | danazol Danocrine 17230-88-5 Chronogyn Winobanin More... |
Iupac Name: | (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol |
InChI: | InChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1 |
InChIKey: | POZRVZJJTULAOH-LHZXLZLDSA-N |
Canonical Smiles: | CC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=C(CC34C)C=NO5 |
Isomeric Smiles: | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5 |
Molecular Weight: | 337.5 |
Molecular Formula: | C22H27NO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
danazol
Molecular Weight: | 337.5 |
Molecular Formula: | C22H27NO2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 25 |
Complexity: | 677 |
Synonyms
danazol
| danazol | danazol |
|---|---|
danazol |
Danocrine |
17230-88-5 |
Chronogyn |
Winobanin |
Danol |
Cyclomen |
Danazolum |
Ladogal |
Danzol |
Danatrol |
Danazol, USP |
UNII-N29QWW3BUO |
WIN-17757 |
WIN 17,757 |
Danazole |
N29QWW3BUO |
WIN 17757 |
Danovaol |
CHEBI:4315 |
(1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta7,8phenanthro3,2-disoxazol-1-ol |
Danokrin |
NCGC00164400-01 |
Danogen |
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)- |
DSSTox_CID_2880 |
Danazolum INN-Latin |
NSC 270916 |
DSSTox_RID_76772 |
DSSTox_GSID_22880 |
Bonzol |
Danocrine (TN) |
SMR000058321 |
CCRIS 6747 |
EINECS 241-270-1 |
Vasaloc |
17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol |
Optina |
Pregna-2,4-dien-20-yno2,3-disoxazol-17-ol, (17alpha)- |
17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol |
17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol |
NSC270916 |
NSC-270916 |
Win 17, 757 |
Prestwick_150 |
CAS-17230-88-5 |
Danazol USAN:USP:INN:BAN:JAN |
ethynyl(dimethyl)?ol |
2,3-Isoxazolethisterone |
Prestwick0_000105 |
Prestwick1_000105 |
Prestwick2_000105 |
Prestwick3_000105 |
CHEMBL1479 |
SCHEMBL21107 |
BSPBio_000090 |
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo11.7.0.0^{2,10}.0^{4,8}.0^{14,18}icosa-4(8),5,9-trien-17-ol |
MLS001066617 |
MLS001306473 |
Danazol (JP17/USP/INN) |
SPBio_002029 |
BPBio1_000100 |
GTPL6942 |
DTXSID2022880 |
2,4,17alpha-Pregnadien-20-yno2,3-d-isoxa-zol-17-ol |
Win-17,757 |
HMS1568E12 |
HMS2090A22 |
HMS2095E12 |
HMS2231M08 |
HMS3259M10 |
HMS3712E12 |
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)- |
1,2oxazolo4,5:2,3-17alpha-pregn-4-en-20-yn-17-ol |
17.Alpha.-Pregna-2, {4-dien-20-yno2,3-disoxazol-17-ol} |
BCP11914 |
HY-B1029 |
ZINC3881958 |
Tox21_112114 |
Tox21_301940 |
BDBM50423541 |
MFCD00056838 |
s9506 |
AKOS015961192 |
Tox21_112114_1 |
AC-6836 |
CCG-220105 |
CS-4547 |
Danazol 100 microg/mL in Acetonitrile |
DB01406 |
MCULE-5533294331 |
NC00557 |
NCGC00179665-01 |
NCGC00179665-02 |
NCGC00179665-04 |
NCGC00255335-01 |
(1R,3aS,3bR,10aR,10bS,12aS)-1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta7,8phenanthro3,2-d1,2oxazol-1-ol |
1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta7,8phenanthro3,2-disoxazol-1-ol |
AS-13035 |
C06938 |
D00289 |
199957-EP2272825A2 |
199957-EP2275420A1 |
230D885 |
Q419652 |
SR-01000760722 |
SR-05000000445 |
SR-01000760722-2 |
SR-05000000445-2 |
W-107864 |
17a-Pregna-2,4-dien-20-yno2,3-disoxazol-17-ol |
BRD-K48970916-001-03-0 |
(17a)-Pregna-2,4-dien-20-yno2,3-disoxazol-17-ol |
17a-Pregna-2,4-dien-20-yne-2,3-disoxazole-17b-ol |
1-(P-TOSYL)-3,4,4-TRIMETHYL-2-IMIDAZOLINIUMIODIDE |
17 alpha-pregna-2,4-dien-20-yno2,3-D isoxazol-17 beta-ol |
Pregna-2, {4-dien-20-yno2,3-disoxazol-17-ol,} (17.alpha.)- |
Pregna-2,4-diene-20-yno2,3-d isoxazol-17-ol, (17.alpha.) |
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo11.7.0.02,10.04,8.014,18icosa-4(8),5,9-trien-17-ol |
1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-Cyclopenta7,8phenanthro3,2-disoxazol-1-ol |
1H-Cyclopenta7,8phenanthro3,2-disoxazole- pregna-2,4-dien-20-yno2,3-disoxazol-17-ol deriv. |
Experimental Data
danazol
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 13 | S | N2 | 24134630 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 13 | S | N2 | 33683565 | Active |
Experimental Data Visualization
danazol
Statistics Data
danazol
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 13 | 2 | 2 |
Statistics Data Visualization
danazol
