Compound Summary
Compound Information
clofibrate
Compound Name: | clofibrate |
Compound CID: | 2796 |
Synonyms: | clofibrate 637-07-0 Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate Ethyl clofibrate Atromid More... |
Iupac Name: | ethyl 2-(4-chlorophenoxy)-2-methylpropanoate |
InChI: | InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3 |
InChIKey: | KNHUKKLJHYUCFP-UHFFFAOYSA-N |
Canonical Smiles: | CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl |
Isomeric Smiles: | CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl |
Molecular Weight: | 242.7 |
Molecular Formula: | C12H15ClO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
clofibrate
Molecular Weight: | 242.7 |
Molecular Formula: | C12H15ClO3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 16 |
Complexity: | 232 |
Synonyms
clofibrate
| clofibrate | clofibrate |
|---|---|
clofibrate |
637-07-0 |
Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate |
Ethyl clofibrate |
Atromid |
Clofibratum |
Clofibrato |
Liprin |
Atromid-S |
Miscleron |
EPIB |
Angiokapsul |
Antilipid |
Antilipide |
Arterioflexin |
Arterosol |
Ateriosan |
Athebrate |
Atheromide |
Atheropront |
Chlorphenisate |
Clofibate |
Lipofacton |
Ticlobran |
Amotril |
Anparton |
Ateculon |
Atrolen |
Atromida |
Lipavil |
Lipavlon |
Lipomid |
Liprinal |
Xyduril |
Apolan |
Amotril S |
Ethyl chlorophenoxyisobutyrate |
Athranid-wirkstoff |
Atromidin |
Bioscleran |
Cartagyl |
Citiflus |
Claripex |
Clofibram |
Clofibrat |
Clofinit |
Clofipront |
Fibralem |
Gerastop |
Hyclorate |
Klofibrat |
Klofiran |
Levatrom |
Lipidsenker |
Liponorm |
Liporeduct |
Lobetrin |
Normalip |
Persantinat |
Regardin |
Serotinex |
Skleromexe |
Atrovis |
Azionyl |
Bresit |
Clobrat |
Clofar |
Delipid |
Deliva |
Lipamid |
Liporil |
Liposid |
Normat |
Regelan |
Sklero |
Dura clofibrat |
Sklero-Tablinen |
neo-Atomid |
Neo-Atromid |
Atromid S |
Claripex CPIB |
Clobren-SF |
ELPI |
Cinnarizin |
Cloberat |
Misclerone |
Normolipol |
Robigram |
Skerolip |
Artevil |
Negalip |
Normet |
Recolip |
Scrobin |
Yoclo |
Sklero-tabuls |
Regelan N |
2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester |
Lipide 500 |
Chlorfenisate |
Oxan 600 |
Ethyl 2-(p-chlorophenoxy)isobutyrate |
Artes |
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester |
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester |
Ethyl para-chlorophenoxyisobutyrate |
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate |
NSC-79389 |
ICI 28257 |
Ethyl p-chlorophenoxyisobutyrate |
AY 61123 |
AY-61123 |
alpha-p-Chlorophenoxyisobutyryl ethyl ester |
Ethyl 2-(4-chlorophenoxy)isobutyrate |
alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester |
UNII-HPN91K7FU3 |
Ethyl 2-(p-chlorophenoxy)-2-methylpropionate |
19 more names available |
ICI-28257 |
CHEMBL565 |
HPN91K7FU3 |
Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl ester |
CHEBI:3750 |
Propanoic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester |
Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester |
Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester |
.alpha.-p-Chlorophenoxyisobutyryl ethyl ester |
2-(4-Chlorophenoxy)isobutyric Acid Ethyl Ester |
NSC79389 |
MFCD00000615 |
.alpha.-(p-Chlorophenoxy)isobutyric acid, ethyl ester |
NCGC00015257-08 |
Sklerepmexe |
Serofinex |
Sklerolip |
Skleromex |
Clofibrato Spanish |
Ethyl .alpha.-(4-chlorophenoxy)isobutyrate |
Ethyl .alpha.-(p-chlorophenoxy)isobutyrate |
DSSTox_CID_336 |
Sklero-tablinene |
Clobren-5F |
DSSTox_RID_75521 |
Vincamin compositum |
Clofibratum INN-Latin |
DSSTox_GSID_20336 |
Clofibrato INN-Spanish |
ethyl 2-(4-chlorophenyl)oxy-2-methylpropanoate |
Ethyl .alpha.-(p-chlorophenoxy)-.alpha.-methylpropionate |
Ethyl .alpha.-(4-chlorophenoxy)-.alpha.-methylpropionate |
Abitrate |
CAS-637-07-0 |
SMR000058279 |
CCRIS 177 |
clofibrate (CLOF) |
Ethyl-alpha-p-chlorophenoxy-isobutyrate |
Ethyl alpha-(4-chlorophenoxy)isobutyrate |
Ethyl alpha-(p-chlorophenoxy)isobutyrate |
HSDB 3038 |
SR-01000075544 |
EINECS 211-277-4 |
ATROMID-S (TN) |
NSC 79389 |
BRN 1913459 |
BML2-F02 |
Clofibrate liquid |
Clobren SF |
Clofibrate, liquid |
Ethyl alpha-(4-chlorophenoxy)-alpha-methylpropionate |
Ethyl alpha-(p-Chlorophenoxy)-alpha-methylpropionate |
Clofibrate USAN:USP:INN:BAN:JAN |
Isobutyric acid, alpha-(p-chlorophenoxy)-, ethyl ester |
Ethyl 2-(para-chlorophenoxy)-2-methylpropionate (IUPAC) |
Spectrum_001735 |
p-Chlorophenoxyisobutyric acid ethyl ester |
Spectrum2_001209 |
Spectrum4_000223 |
Spectrum5_001133 |
Lopac-C-6643 |
UPCMLD-DP019 |
C 6643 |
ethyl 2-(4-chlorophenoxy)-2-methyl-propanoate |
SCHEMBL2356 |
NCIOpen2_004739 |
BIDD:PXR0178 |
CBiol_001860 |
Lopac0_000306 |
BSPBio_001577 |
KBioGR_000297 |
KBioGR_000885 |
KBioSS_000297 |
KBioSS_002215 |
MLS001336011 |
MLS001336012 |
MLS002153494 |
BIDD:GT0172 |
DivK1c_000822 |
DivK1c_000926 |
SPBio_000998 |
Clofibrate (JP17/USP/INN) |
GTPL2667 |
2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester |
DTXSID3020336 |
UPCMLD-DP019:001 |
BCBcMAP01_000104 |
HMS502J04 |
HMS502O08 |
KBio1_000822 |
KBio1_000926 |
KBio2_000297 |
KBio2_002215 |
KBio2_002865 |
KBio2_004783 |
KBio2_005433 |
KBio2_007351 |
KBio3_000593 |
KBio3_000594 |
WLN: GR DOX1&1&VO2 |
ZINC56648 |
Clofibrate, >=98.0% (GC) |
NINDS_000822 |
NINDS_000926 |
Bio1_000146 |
Bio1_000635 |
Bio1_001124 |
Bio2_000297 |
Bio2_000777 |
HMS1361O19 |
HMS1791O19 |
HMS1989O19 |
HMS2089P03 |
HMS2093G07 |
HMS2233C17 |
HMS3260N14 |
HMS3373C06 |
HMS3402O19 |
HMS3715J03 |
Pharmakon1600-01503429 |
EBD52899 |
HY-B0287 |
Tox21_110116 |
Tox21_202414 |
Tox21_300277 |
Tox21_500306 |
BDBM50085047 |
CCG-40281 |
NSC758474 |
SBB099633 |
AKOS015889383 |
Tox21_110116_1 |
DB00636 |
LP00306 |
MCULE-9236719628 |
NSC-758474 |
SDCCGSBI-0050294.P004 |
IDI1_000822 |
IDI1_000926 |
IDI1_034047 |
Clofibrate, analytical reference material |
NCGC00015257-01 |
NCGC00015257-02 |
NCGC00015257-03 |
NCGC00015257-04 |
NCGC00015257-05 |
NCGC00015257-06 |
NCGC00015257-07 |
NCGC00015257-09 |
NCGC00015257-10 |
NCGC00015257-11 |
NCGC00015257-12 |
NCGC00015257-14 |
NCGC00015257-22 |
NCGC00093755-01 |
NCGC00093755-03 |
NCGC00093755-04 |
NCGC00093755-05 |
NCGC00093755-06 |
NCGC00093755-07 |
NCGC00093755-08 |
NCGC00254073-01 |
NCGC00259963-01 |
NCGC00260991-01 |
AC-33179 |
AS-14127 |
K009 |
NCI60_041748 |
Ethyl .alpha.-p-(chlorophenoxy)isobutyrate |
SBI-0050294.P003 |
AB0013973 |
DB-054528 |
EU-0100306 |
FT-0625865 |
FT-0665112 |
S1820 |
ST50319977 |
2-(p-Chlorophenoxy)isobutyric acid ethyl ester |
C06916 |
D00279 |
F20382 |
AB00052358-07 |
AB00052358-08 |
AB00052358_09 |
AB00052358_10 |
Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate # |
A834483 |
ethyl 2-(4-chloranylphenoxy)-2-methyl-propanoate |
Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl este |
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, 99% |
Q2701912 |
SR-01000075544-1 |
SR-01000075544-4 |
SR-01000075544-5 |
SR-01000075544-8 |
Z53835984 |
2-(p-chlorophenoxy)-2-methylPropanoic acid ethyl ester |
2-(p-chlorophenoxy)-2-methylpropionic acid ethyl ester; |
2-(4-Chloro-phenoxy)-2-methyl-propionic acid ethyl ester |
Clofibrate, European Pharmacopoeia (EP) Reference Standard |
Isobutyric acid, .alpha.-(p-chlorophenoxy)-, ethyl ester |
Clofibrate, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
clofibrate
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 1 | umol/L | 21.6 | 22.6 | 0.05 | 28.1 | 27.2 | -0.03 | NS | N2 | 23603800 | Inactive | |
| Caenorhabditis elegans | 10 | umol/L | 21.6 | 25.1 | 0.16 | 28.1 | 33.8 | 0.2 | S | N2 | 23603800 | Active | |
| Caenorhabditis elegans | 0.1 | umol/L | 21.6 | 22 | 0.02 | 28.1 | 25.9 | -0.08 | NS | N2 | 23603800 | Inactive | |
| Caenorhabditis elegans | 33 | umol/L | -5 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 10 | umol/L | 21.6 | 23 | 0.06 | 28.1 | 34.2 | 0.22 | S | N2 | 23603800 | Active |
Experimental Data Visualization
clofibrate
Statistics Data
clofibrate
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.16 | 0.22 | 2 | 5 |
Statistics Data Visualization
clofibrate
