Compound Summary
Compound Information
cimetidine
Compound Name: | cimetidine |
Compound CID: | 2756 |
Synonyms: | cimetidine 51481-61-9 Tagamet Eureceptor Tametin More... |
Iupac Name: | 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine |
InChI: | InChI=1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14) |
InChIKey: | AQIXAKUUQRKLND-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(N=CN1)CSCCNC(=NC)NC#N |
Isomeric Smiles: | CC1=C(N=CN1)CSCCNC(=NC)NC#N |
Molecular Weight: | 252.34 |
Molecular Formula: | C10H16N6S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
cimetidine
Molecular Weight: | 252.34 |
Molecular Formula: | C10H16N6S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 17 |
Complexity: | 296 |
Synonyms
cimetidine
| cimetidine | cimetidine |
|---|---|
cimetidine |
51481-61-9 |
Tagamet |
Eureceptor |
Tametin |
Dyspamet |
Ulcedine |
Acinil |
Cimetag |
Tratul |
Ulcedin |
Acibilin |
Gastromet |
Cimetum |
Edalene |
Ulcimet |
Ulcomet |
Cimal |
Ulhys |
Tagamet Hb |
Cimetidine Hcl |
Tagamet Hb 200 |
SKF-92334 |
Cimetidina |
Ulcomedina |
Valmagen |
Cimetidinum |
SKF 92334 |
1-cyano-2-methyl-3-2-(5-methyl-1H-imidazol-4-yl)methylsulfanylethylguanidine |
N-Cyano-N-methyl-N-2-(4-methyl-1H-imidazol-5-yl)methylthioethylguanidine |
2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine |
1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine |
UNII-80061L1WGD |
CHEBI:3699 |
C10H16N6S |
N-Cyano-N-methyl-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine |
CHEMBL30 |
Metracin |
MFCD00133296 |
NSC-335308 |
Brumetadina |
2-cyano-1-methyl-3-(2-{(5-methyl-1H-imidazol-4-yl)methylsulfanyl}ethyl)guanidine |
MLS000069791 |
76181-71-0 |
Gastrobitan |
Ulcestop |
Ulcofalk |
Evicer |
Peptol |
80061L1WGD |
51481-61-9 (free) |
Guanidine, N-cyano-N-methyl-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-" |
Guanidine, N-cyano-N-methyl-N-2-(5-methyl-1H-imidazol-4-yl)methylthioethyl-" |
Guanidine, N-cyano-N-Methyl-N-2-(5-Methyl-1H-iMidazol-4-yl)Methylthioethyl-, (Z)- |
NSC 335308 |
NCGC00015240-06 |
SMR000038895 |
DSSTox_CID_329 |
2-cyano-1-methyl-3-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine |
DSSTox_RID_75517 |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine" |
N-cyano-N-methyl-N-(2-((5-methyl-1H-imidazol-4-yl)methylsulfanyl)ethyl)guanidine |
Cimetidinum INN-Latin |
DSSTox_GSID_20329 |
Cimetidina INN-Spanish |
Brumetidina |
DRG-0150 |
(E)-2-cyano-1-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine |
(Z)-3-cyano-1-methyl-2-(2-{(5-methyl-1H-imidazol-4-yl)methylsulfanyl}ethyl)guanidine |
1-cyano-2-methyl-3-(2-{(5-methyl-1H-imidazol-4-yl)methylsulfanyl}ethyl)guanidine |
2-cyano-1-methyl-3-2-(5-methyl-1H-imidazol-4-yl)methylsulfanylethylguanidine |
Guanidine, N-cyano-N-methyl-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-" |
Guanidine, N-cyano-N-methyl-N-2-(5-methyl-1H-imidazol-4-yl)methylthioethyl- |
Tagamet (TN) |
Cimetidine, A Type |
CCRIS 3247 |
Equaline acid reducer |
HSDB 3917 |
Topcare heartburn relief |
SR-01000075260 |
SR-05000001434 |
FPF 1002 |
EINECS 257-232-2 |
cemitidine |
metidine |
1-cyano-2-methyl-3-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)guanidine |
1-cyano-2-methyl-3-2-(5-methyl-1H-imidazol-4-yl)methylthioethylguanidine |
Cimetidine,(S) |
Prestwick_65 |
{(1E)-1-(methylamino)-4-(4-methylimidazol-5-yl)methylthio-2-azabut-1-enyl}am inocarbonitrile |
Cimetidine (Tagamet) |
Cimetidine USAN:USP:INN:BAN:JAN |
CIMETIDINE A |
Spectrum_000495 |
Tocris-0902 |
Opera_ID_314 |
Prestwick3_000026 |
Spectrum2_000782 |
Spectrum3_001389 |
Spectrum4_000812 |
Spectrum5_001541 |
Lopac-C-4522 |
UPCMLD-DP029 |
2-Cyano-1-methyl-3-2-(5-methyl-1H-imidazol-4-yl-methylthio)ethylguanidine |
C 4522 |
SCHEMBL1093 |
SCHEMBL1094 |
SKF-92334; Tagamet |
Guanidine, N-cyano-N-methyl-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio) ethyl)- |
Lopac0_000293 |
BSPBio_000091 |
BSPBio_002978 |
KBioGR_001323 |
KBioSS_000975 |
US9138393, Cimetidine |
US9144538, Cimetidine |
MLS001148596 |
MLS002153265 |
MLS002154178 |
DivK1c_000166 |
SPECTRUM1500684 |
SPBio_000884 |
BPBio1_000101 |
Cimetidine (JP17/USP/INN) |
GTPL1231 |
DTXSID4020329 |
SCHEMBL11282982 |
UPCMLD-DP029:001 |
BDBM22889 |
HMS500I08 |
KBio1_000166 |
KBio2_000975 |
KBio2_003543 |
KBio2_006111 |
KBio3_002198 |
NINDS_000166 |
BDBM181119 |
HMS1921C14 |
HMS2089O03 |
HMS2092I14 |
HMS2095E13 |
HMS2232F16 |
HMS3259M15 |
HMS3260L08 |
HMS3267A03 |
HMS3369L10 |
HMS3414I17 |
HMS3651E21 |
HMS3678I17 |
HMS3712E13 |
HMS3750I05 |
HMS3884I12 |
Pharmakon1600-01500684 |
Cimetidine 1.0 mg/ml in Methanol |
EX-A1088 |
Tox21_110106 |
Tox21_201160 |
Tox21_500293 |
BDBM50103595 |
BDBM50403559 |
CCG-40160 |
NSC335308 |
NSC757428 |
s1845 |
SBB057794 |
STK528249 |
ZINC18115268 |
1-Cyano-2-methyl-3-2-(5-methylimidazol-4-yl)methylthioethylguanidine |
AKOS005460997 |
AKOS015900557 |
AKOS015951369 |
AKOS016003398 |
AKOS016340377 |
AKOS026749950 |
AKOS032949548 |
Tox21_110106_1 |
AB03708 |
AC-8100 |
CCG-204388 |
CCG-220026 |
CCG-221597 |
DB00501 |
KS-5087 |
LP00293 |
MCULE-2885245608 |
NC00501 |
NSC 757428 |
NSC-757428 |
SDCCGSBI-0050281.P005 |
IDI1_000166 |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylsulfanyl}ethyl)guanidine" |
N-Cyano-N-methyl-N-2-(5-methyl-1H-imidazol-4-yl)methylthioethylguanidine" |
N-Cyano-N-methyl-2-5-methyl-1H-imidazol-4-ylmethylthioethylguanidine |
NCGC00015240-01 |
NCGC00015240-02 |
NCGC00015240-03 |
NCGC00015240-04 |
NCGC00015240-05 |
NCGC00015240-07 |
NCGC00024859-01 |
NCGC00024859-02 |
NCGC00024859-03 |
NCGC00024859-04 |
NCGC00024859-05 |
NCGC00091439-01 |
NCGC00091439-02 |
NCGC00091439-03 |
NCGC00091439-04 |
NCGC00091439-05 |
NCGC00091439-07 |
NCGC00091439-10 |
NCGC00185989-01 |
NCGC00188961-01 |
NCGC00258712-01 |
NCGC00260978-01 |
2984-61-4 |
943920-67-0 |
Cimetidine 100 microg/mL in Acetonitrile |
H505 |
HY-14289 |
NCI60_002936 |
SBI-0050281.P004 |
AB0013083 |
DB-051971 |
EU-0100293 |
FT-0602955 |
ST50411770 |
SW196380-2 |
C06952 |
D00295 |
F16651 |
J10340 |
AB00052157-03 |
AB00052157_04 |
AB00052157_05 |
481C619 |
A828616 |
L000186 |
L003827 |
L013434 |
Q409492 |
SR-05000001750 |
Q-200855 |
Q-200856 |
SR-01000075260-1 |
SR-01000075260-3 |
SR-05000001434-1 |
SR-05000001434-2 |
SR-05000001750-1 |
BRD-K18618618-001-01-6 |
BRD-K34157611-001-04-6 |
BRD-K34157611-001-07-9 |
Z1259192068 |
Cimetidine, European Pharmacopoeia (EP) Reference Standard |
4H -Dithieno3,2-b :2,3-d pyrrole, 4-(1-octylnonyl)- |
Cimetidine, United States Pharmacopeia (USP) Reference Standard |
1-Ethyl-2,3-dimethylimidazolium tosylate, 98% EDiMIM TOS |
1-Cyan-2-methyl-3-(2-{(5-methylimidazol-4-yl)methylthio}ethyl)guanidin |
Cimetidine, Pharmaceutical Secondary Standard; Certified Reference Material |
N"-cyano-N-methyl-N\-2-(5-methylimidazol-4-ylmethylthio)ethyl-guanidine |
N"-cyano-N-methyl-N\-2-(5-methylimidazol-4-ylmethylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl)methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((5-methyl-4-imidazolyl)methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-(5-methyl-4-imidazolylmethylthio)ethylguanidine |
(Z)-1-cyano-2-methyl-3-(2-{(5-methyl-1H-imidazol-4-yl)methylsulfanyl}ethyl)guanidine |
2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)-benzenesulfonamide(Cimetidine) |
2-Methyl-8-phenethyl-imidazo1,2-apyridine-3-carboxylic acid methyl ester(cimetidine) |
2-methylamino-2-2-(4-methyl-1H-5-imidazolylmethylsulfanyl)ethylamino-(E)-1-imino cyanide |
3-cyano-2-methyl-1-2-(5-methyl-1H-imidazol-4-yl)methylsulfanylethylguanidine |
4-(((2-(((cyanoamino)(methylamino)methylene)amino)ethyl)thio)methyl)-5-methyl-1H-imidazole |
Cimetidine for peak identification, European Pharmacopoeia (EP) Reference Standard |
Cimetidine for system suitability, European Pharmacopoeia (EP) Reference Standard |
Guanidine, N-cyano-N-methyl-N-2-5-methyl-1H-imidazol-4-yl)methylthioethyl-" |
N-cyano-N-methyl-N-(2-((5-methyl-1h-imidazol-4-yl)-methylthio)ethyl)guanidine |
N-cyano-N\-methyl-N"- 2-((5-methyl-4-imidazolyl)methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl) methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl)- methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl)-methylthio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl)methyl-thio)ethylguanidine |
N-cyano-N\-methyl-N"-2-((4-methyl-5-imidazolyl)methylthio)ethyl) guanidine |
N-cyano-N\-methyl-N"-2-((5-methyl-4-imidazolyl)methylthio)-ethylguanidine |
N-cyano-N\-methyl-N"-2-((5-methyl-4-imidazolyl)methylthio)ethyl-guanidine |
N-cyano-N\-methyl-N"-2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethylguanidine |
N-Cyano-N-methyl-N-(2-((5-methyl-1H-imidazol-4-yl)methylsulfanyl)ethyl)guanidine #" |
N-Cyano-N-methyl-N-2-(5-methyl-1H-imidazol-4-yl)methylthioethylguanidine" |
N-cyano-N-methyl-N-2-(5-methylimidazol-4-ylmethylthioethyl)guanidine |
N-cyano-N\-methyl-N-"-2-((4-methyl-5-imidazolyl)methylthio)ethylguanidine |
N-methyl-N\-{2-(5-methylimidazol-4-yl)-methylthio-ethyl}-N"-cyanoguanidine |
N-methyl-N-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl-1-cyanoiminomethanediamine |
N-methyl-N-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylimino(-N-cyano)methanediaminem |
N-tert-Butyl-N-4-(1H-imidazol-4-yl)-phenyl-formamidine(cimetidine)" |
(Cimetidine) N-Methyl-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-guanidine,cyanide |
(cimetidine) N-methyl-N-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylcyanoiminomethanediamine |
(Cimetidine)N-methyl-N-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylcyanomethyliminomethanediamine |
2-methylamino-2-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylamino-(Z)-1-imino cyanide(cimetidine) |
Guanidine,N-cyano-N-Methyl-N-2-(5-Methyl-1H-iMidazol-4-yl)Methylthioethyl-,(Z)-" |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine" |
N-cyano-N-methyl-N-({(5-methyl-1H-imidazol-4-yl)methylthio}methyl)guanidine(cimetidine)" |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methyl-lambda~4~-sulfanyl}ethyl)guanidine" |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine" |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine (Cimetidine)" |
N-cyano-N-methyl-N-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)guanidine(cimetidine)" |
N-Cyano-N-methyl-N-(2-(((5-methyl-1H-imidazol-4-yl) methyl)thio)ethyl)guanidine(Cimetidine)" |
N-cyanomethyl-N-methyl-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-guanidine ( Cimetidine)" |
N-Methyl-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-cyanoguanidine(cimetidine)" |
N-Methyl-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-N-Cyano-guanidine" |
N-Methyl-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-N-cyano-guanidine(Cimetidine)" |
N-methyl-N-cyano-N-2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl-guanidine |
N-methyl-N-2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylcyanoiminomethanediamine (cimetidine) |
Experimental Data
cimetidine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
cimetidine
Statistics Data
cimetidine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
cimetidine
