Compound Summary
Compound Information
capsazepine
Compound Name: | capsazepine |
Compound CID: | 2733484 |
Synonyms: | capsazepine 138977-28-3 N-2-(4-Chlorophenyl)ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide capsazepin UNII-LFW48MY844 More... |
Iupac Name: | N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide |
InChI: | InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) |
InChIKey: | DRCMAZOSEIMCHM-UHFFFAOYSA-N |
Canonical Smiles: | C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O |
Isomeric Smiles: | C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O |
Molecular Weight: | 376.9 |
Molecular Formula: | C19H21ClN2O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
capsazepine
Molecular Weight: | 376.9 |
Molecular Formula: | C19H21ClN2O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 25 |
Complexity: | 445 |
Synonyms
capsazepine
| capsazepine | capsazepine |
|---|---|
capsazepine |
138977-28-3 |
N-2-(4-Chlorophenyl)ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide |
capsazepin |
UNII-LFW48MY844 |
N-2-(4-chlorophenyl)ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide |
MFCD00153778 |
CHEMBL391997 |
LFW48MY844 |
ST50826300 |
CHEBI:70773 |
N-2-(4-chlorophenyl)ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide |
N-(4-chlorophenethyl)-7,8-dihydroxy-4,5-dihydro-1H-benzocazepine-2(3H)-carbothioamide |
2-2-(4-chlorophenyl)ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine |
N-(2-4-chlorophenylethyl)-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide |
N-2-(4-chlorophenyl)ethyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine-2-carbothioamide |
SR-01000075437 |
capasazepine |
N-(2-(4-chlorophenyl)ethyl)-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-Benzazepine-2-carbothioamide |
Tocris-0464 |
Lopac-C-191 |
Lopac0_000373 |
BSPBio_001550 |
KBioGR_000270 |
KBioSS_000270 |
MLS002153524 |
SCHEMBL122421 |
GTPL2461 |
BDBM20284 |
KBio2_000270 |
KBio2_002838 |
KBio2_005406 |
KBio3_000539 |
KBio3_000540 |
DTXSID20160852 |
Bio1_000394 |
Bio1_000883 |
Bio1_001372 |
Bio2_000270 |
Bio2_000750 |
HMS1361N12 |
HMS1791N12 |
HMS1989N12 |
HMS2230F13 |
HMS3261K07 |
HMS3266C14 |
HMS3372M06 |
HMS3402N12 |
HMS3411O03 |
HMS3650G17 |
HMS3675O03 |
HMS3748G07 |
HMS3886D06 |
NK101 |
BCP12782 |
ZINC3871859 |
Tox21_500373 |
1660AH |
s8137 |
AKOS024458271 |
Capsazepine, >=98% (HPLC), solid |
CCG-204468 |
CS-1572 |
LP00373 |
SDCCGSBI-0050361.P002 |
Capsazepine - CAS 138977-28-3 |
IDI1_034020 |
NCGC00015190-01 |
NCGC00015190-02 |
NCGC00015190-03 |
NCGC00015190-04 |
NCGC00015190-05 |
NCGC00015190-06 |
NCGC00015190-07 |
NCGC00015190-14 |
NCGC00024602-01 |
NCGC00024602-02 |
NCGC00024602-03 |
NCGC00024602-04 |
NCGC00261058-01 |
2H-2-Benzazepine-2-carbothioamide, N-2-(4-chlorophenyl)ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy- |
AS-74621 |
HY-15640 |
SMR001230854 |
C-120 |
C-191 |
EU-0100373 |
FT-0664232 |
7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide |
977C283 |
A857043 |
J-007205 |
Q5036336 |
SR-01000075437-1 |
SR-01000075437-3 |
SR-01000075437-7 |
BRD-K44849676-001-03-0 |
N-2-(4-Chlorophenyl)ethyl-1,3,4,5-tetrahydro- |
2-({2-(4-chlorophenyl)ethylamino}thioxomethyl)-1H,3H,4H,5H-benzoeazepine-7 ,8-diol |
N-(4-Chlorophenethyl)-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide |
2-2-(4-Chlorophenyl)ethylaminothiocarbonyl-2,3,4,5-tetrahydro-1H-2-benzazepine-7,8-diol |
6ET |
N-2-(4-chlorophenyl)ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide. |
Experimental Data
capsazepine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 0 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
capsazepine
Statistics Data
capsazepine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0 | 1 | 1 |
Statistics Data Visualization
capsazepine
