Compound Summary
Compound Information
Tacrine hydrochloride
Compound Name: | Tacrine hydrochloride |
Compound CID: | 2723754 |
Synonyms: | Tacrine hydrochloride 1684-40-8 Tacrine HCl 1,2,3,4-tetrahydroacridin-9-amine hydrochloride Hydroaminacrine More... |
Iupac Name: | 1,2,3,4-tetrahydroacridin-9-amine;hydrochloride |
InChI: | InChI=1S/C13H14N2.ClH/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H |
InChIKey: | ZUFVXZVXEJHHBN-UHFFFAOYSA-N |
Canonical Smiles: | C1CCC2=NC3=CC=CC=C3C(=C2C1)N.Cl |
Isomeric Smiles: | C1CCC2=NC3=CC=CC=C3C(=C2C1)N.Cl |
Molecular Weight: | 234.72 |
Molecular Formula: | C13H15ClN2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tacrine hydrochloride
Molecular Weight: | 234.72 |
Molecular Formula: | C13H15ClN2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 16 |
Complexity: | 229 |
Synonyms
Tacrine hydrochloride
| Tacrine hydrochloride | Tacrine hydrochloride |
|---|---|
Tacrine hydrochloride |
1684-40-8 |
Tacrine HCl |
1,2,3,4-tetrahydroacridin-9-amine hydrochloride |
Hydroaminacrine |
Romotal |
Tenakrin |
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE |
UNII-4966RNG0BU |
tacrine.HCl |
Tacrine (hydrochloride) |
9-Acridinamine, 1,2,3,4-tetrahydro-, monohydrochloride |
CI-970 |
1,2,3,4-Tetrahydro-9-acridinamine hydrochloride |
MLS000028845 |
4966RNG0BU |
9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1) |
1,2,3,4-Tetrahydro-9-aminoacridine hydrochloride |
SMR000059105 |
1,2,3,4-tetrahydroacridin-9-amine;hydrochloride |
1,2,3,4-Tetrahydro-9-acridinamine monohydrochloride |
9-amino-1,2,3,4-Tetrahydroacridine hydrochloride dihydrate |
SR-01000075593 |
CAS-1684-40-8 |
CCRIS 7250 |
T.H.A. |
OROS-tacrine |
Tacrine hydrochloride USAN:USP |
tacrine hydrochlorid |
Tacrin hydrochloride |
EINECS 216-867-5 |
1,2,3,4-Tetrahydroacridin-9-amine monohydrochloride |
CI 970 |
Cognex (TN) |
MFCD00150067 |
NSC 72108 |
THA.HCl |
CPD000059105 |
Opera_ID_296 |
DSSTox_CID_6112 |
SCHEMBL3270 |
CHEMBL1677 |
DSSTox_RID_78021 |
DSSTox_GSID_26112 |
Tacrine hydrochloride (USP) |
MLS000758202 |
MLS001401372 |
SPECTRUM2300104 |
9-Amino-1,2,3,4-tetrahydroacridine monohydrochloride |
Acridine, 9-amino-1,2,3,4-tetrahydro-, hydrochloride |
DTXSID1026112 |
CI970 |
Pharmakon1600-02300104 |
ACT08745 |
AMY10870 |
BCP29701 |
HY-B1488 |
NSC72108 |
Tox21_200299 |
Tox21_500036 |
2058AH |
2739AH |
CCG-39606 |
NSC-72108 |
NSC759324 |
s4357 |
AKOS015913476 |
LP00036 |
MCULE-4824739637 |
NC00068 |
NSC-759324 |
Tacrine hydrochloride; THA hydrochloride |
Tetrahydroaminoacridine Monohydrochloride |
NCGC00024908-02 |
NCGC00093554-01 |
NCGC00093554-02 |
NCGC00093554-03 |
NCGC00093554-04 |
NCGC00257853-01 |
NCGC00260721-01 |
1,2,3,4-Tetrahydroacridin-9-amine HCl |
DS-16390 |
DB-043738 |
B6527 |
CS-0013186 |
EU-0100036 |
FT-0633768 |
ST50319524 |
SW033163-6 |
A 3773 |
Acridine,2,3,4-tetrahydro-, monohydrochloride |
D02068 |
F20766 |
5,6,7,8-tetrahydroacridine-9-ylamine, chloride |
A810973 |
J-010457 |
SR-01000075593-1 |
SR-01000075593-3 |
SR-01000075593-9 |
9-Acridinamine,2,3,4,-tetrahydro-, monohydrochloride |
Q27259239 |
SR-01000075593-16 |
ACRIDINE, 1,2,3,4-TETRAHYDRO-9-AMINO-, MONOHYDROCHLORIDE |
Acridine, 9-amino-1,2,3,4-tetrahydro-, monohydrochloride (8CI) |
Tacrine HCl;Hydroaminacrine; NSC72108; NSC-72108; NSC72108 |
Experimental Data
Tacrine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -28 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tacrine hydrochloride
Statistics Data
Tacrine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -28 | 1 | 1 |
Statistics Data Visualization
Tacrine hydrochloride
