Compound Summary
Compound Information
chlorothiazide
Compound Name: | chlorothiazide |
Compound CID: | 2720 |
Synonyms: | chlorothiazide 58-94-6 Diuril Chlorothiazid Chlorthiazide More... |
Iupac Name: | 6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
InChI: | InChI=1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13) |
InChIKey: | JBMKAUGHUNFTOL-UHFFFAOYSA-N |
Canonical Smiles: | C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2 |
Isomeric Smiles: | C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2 |
Molecular Weight: | 295.7 |
Molecular Formula: | C7H6ClN3O4S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
chlorothiazide
Molecular Weight: | 295.7 |
Molecular Formula: | C7H6ClN3O4S2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 17 |
Complexity: | 532 |
Synonyms
chlorothiazide
| chlorothiazide | chlorothiazide |
|---|---|
chlorothiazide |
58-94-6 |
Diuril |
Chlorothiazid |
Chlorthiazide |
Chlotride |
Thiazide |
Chlortiazid |
Chlorosal |
Chlorurit |
Saluretil |
Warduzide |
Alurene |
Clotride |
Diuresal |
Diurilix |
Diurite |
Diutrid |
Salisan |
Salunil |
Saluric |
Yadalan |
Flumen |
Minzil |
Urinex |
Neo-Dema |
Sk-chlorothiazide |
Chlorothiazidum |
Clorotiazida |
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide |
6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
component of Aldoclor |
6-Chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide |
NSC 25693 |
UNII-77W477J15H |
MFCD00058576 |
Diuril (TN) |
MLS000028398 |
CHEBI:3640 |
Chlorthiazid |
Chlorthiazidum |
NSC25693 |
NSC-25693 |
77W477J15H |
CAS-58-94-6 |
NCGC00015242-04 |
Clorotiazide |
Chloriazid |
Chlrosal |
SMR000058429 |
6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
Clorotiazide DCIT |
Diuril Boluses |
6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide |
6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide |
DSSTox_CID_2800 |
DSSTox_RID_76733 |
DSSTox_GSID_22800 |
Diuril Boluses, Veterinary |
C7H6ClN3O4S2 |
Clorotiazida INN-Spanish |
Chlorothiazidum INN-Latin |
chlorothiazid- |
CCRIS 5999 |
HSDB 3030 |
SR-01000075604 |
EINECS 200-404-9 |
6-chloro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide |
6-chloro-1,1-dioxo-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide |
Chlorothiazide (JAN/USP/INN) |
Chlorothiazide USP:INN:BAN |
Prestwick_56 |
Diupres (Salt/Mix) |
Aldoclor (Salt/Mix) |
Spectrum_000134 |
Prestwick0_000251 |
Prestwick1_000251 |
Prestwick2_000251 |
Prestwick3_000251 |
Spectrum2_000154 |
Spectrum3_000342 |
Spectrum4_000280 |
Spectrum5_001446 |
Lopac-C-4911 |
CHEMBL842 |
C 4911 |
cid_2720 |
Lopac0_000254 |
SCHEMBL22329 |
BSPBio_000062 |
BSPBio_002003 |
KBioGR_000780 |
KBioSS_000594 |
BIDD:GT0635 |
DivK1c_000675 |
SPECTRUM1500180 |
SPBio_000288 |
SPBio_002281 |
BPBio1_000070 |
GTPL4835 |
CHEMBL3392493 |
DTXSID0022800 |
BDBM39351 |
Chlorothiazide, thiazide diuretic |
HMS502B17 |
KBio1_000675 |
KBio2_000594 |
KBio2_003162 |
KBio2_005730 |
KBio3_001223 |
NINDS_000675 |
HMS1568D04 |
HMS1920K15 |
HMS2091C18 |
HMS2095D04 |
HMS2232N22 |
HMS3259K15 |
HMS3260D10 |
HMS3370A15 |
HMS3655M13 |
HMS3712D04 |
Pharmakon1600-01500180 |
BCP24474 |
HY-B0224 |
ZINC3872055 |
Tox21_110107 |
Tox21_200972 |
Tox21_500254 |
WLN: T66 BSWM ENJ HG ISZW |
6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
6-chloro-4H-benzoe1,2,4thiadiazine-7-sulfonamide 1,1-dioxide |
CCG-38953 |
NSC756682 |
s1641 |
AKOS015896601 |
AKOS024319450 |
Tox21_110107_1 |
DB00880 |
LP00254 |
MCULE-3497410863 |
NC00500 |
NSC-756682 |
SDCCGSBI-0050242.P005 |
IDI1_000675 |
NCGC00015242-01 |
NCGC00015242-02 |
NCGC00015242-03 |
NCGC00015242-05 |
NCGC00015242-06 |
NCGC00015242-07 |
NCGC00015242-08 |
NCGC00015242-09 |
NCGC00015242-10 |
NCGC00015242-12 |
NCGC00015242-13 |
NCGC00015242-19 |
NCGC00091042-01 |
NCGC00091042-02 |
NCGC00091042-03 |
NCGC00091042-04 |
NCGC00091042-05 |
NCGC00258525-01 |
NCGC00260939-01 |
AC-18732 |
AS-11760 |
SBI-0050242.P004 |
AB0010688 |
EU-0100254 |
FT-0664953 |
Hydrochlorothiazide impurity, chlorothiazide- |
SW219268-1 |
Chlorothiazide 100 microg/mL in Acetonitrile |
C07461 |
D00519 |
D89501 |
AB00051940-04 |
AB00051940_05 |
AB00051940_06 |
102632-EP2270011A1 |
102632-EP2272841A1 |
102632-EP2277879A1 |
102632-EP2298776A1 |
102632-EP2301936A1 |
Q2603363 |
SR-01000075604-1 |
SR-01000075604-3 |
SR-01000075604-5 |
W-105353 |
BRD-K88682005-001-05-9 |
BRD-K88682005-001-07-5 |
Z1691545266 |
6-Chloro-7-sulfamoyl-2H-1,4-benzothiadiazine 1,1-dioxide |
6-Chloro-2H-1,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
6-chloro-4H-1,2,4-benzathiadiazine-7-sulfonamide-1,1-dioxide |
Chlorothiazide, European Pharmacopoeia (EP) Reference Standard |
2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide |
6-chloro-1,1-dioxo-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
6-chloro-1,1-dioxo-4H-1$l^{6,2,4-benzothiadiazine-7-sulfonamide |
6-chloro-2H-benzoe1,2,4thiadiazine-7-sulfonamide 1,1-dioxide |
Chlorothiazide, United States Pharmacopeia (USP) Reference Standard |
6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo1,2,4thiadiazine-7-sulfonic acid amide |
Chlorothiazide, Pharmaceutical Secondary Standard; Certified Reference Material |
Experimental Data
chlorothiazide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
chlorothiazide
Statistics Data
chlorothiazide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3 | 1 | 1 |
Statistics Data Visualization
chlorothiazide
