Compound Summary
Compound Information
chloroquine
Compound Name: | chloroquine |
Compound CID: | 2719 |
Synonyms: | chloroquine 54-05-7 Aralen Chlorochin Chloraquine More... |
Iupac Name: | 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine |
InChI: | InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21) |
InChIKey: | WHTVZRBIWZFKQO-UHFFFAOYSA-N |
Canonical Smiles: | CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl |
Isomeric Smiles: | CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl |
Molecular Weight: | 319.9 |
Molecular Formula: | C18H26ClN3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
chloroquine
Molecular Weight: | 319.9 |
Molecular Formula: | C18H26ClN3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 22 |
Complexity: | 309 |
Synonyms
chloroquine
| chloroquine | chloroquine |
|---|---|
chloroquine |
54-05-7 |
Aralen |
Chlorochin |
Chloraquine |
Artrichin |
Chloroquinium |
Chloroquina |
Reumachlor |
Capquin |
Chemochin |
Chlorquin |
Clorochina |
Malaquin |
Arthrochin |
Bemasulph |
Benaquin |
Bipiquin |
Chingamin |
Cidanchin |
Cocartrit |
Dichinalex |
Gontochin |
Heliopar |
Iroquine |
Klorokin |
Lapaquin |
Mesylith |
Pfizerquine |
Quinachlor |
Quinercyl |
Quinilon |
Quinoscan |
Sanoquin |
Silbesan |
Solprina |
Sopaquin |
Tresochin |
Amokin |
Bemaco |
Elestol |
Imagon |
Malaren |
Malarex |
Neochin |
Roquine |
Siragan |
Trochin |
Nivaquine B |
Bemaphate |
Resoquine |
Nivaquine |
Chlorochine |
Chloroquinum |
Cloroquina |
Quingamine |
Avloclor |
Resochin |
Ronaquine |
Khingamin |
N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine |
Avlochlor |
Nivachine |
Quinagamin |
Quinagamine |
Resochen |
Resoquina |
Reumaquin |
Arechin |
Delagil |
Tanakan |
WIN 244 |
1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- |
RP 3377 |
W 7618 |
Chloroin |
Miniquine |
Rivoquine |
Tanakene |
Arolen |
7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline |
CHEBI:3638 |
N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine |
{4-(7-chloroquinolin-4-yl)aminopentyl}diethylamine |
Gontochin phosphate |
CHEMBL76 |
SN 6718 |
Ipsen 225 |
Chlorochinum |
4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine |
N(sup 4)-(7-Chloro-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl-1,4-pentanediamine |
MFCD00024009 |
NSC187208 |
NSC-187208 |
SN 7618 |
Chloroquine (VAN) |
Clorochina DCIT |
7-Chloro-4-4-(diethylamino)-1-methylbutylaminoquinoline |
Quinoline, 7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)- |
3377 RP |
CQ |
SN-7618 |
1,4-Pentanediamine, N(sup 4)-(7-chloro-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl- |
ST 21 (pharmaceutical) |
Chloroquinum INN-Latin |
Cloroquina INN-Spanish |
3377 RP opalate |
Chloroquin |
Quinoline, 7-chloro-4-4-(diethylamino)-1-methylbutylamino- |
N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine |
ST 21 |
(+-)-Chloroquine |
NSC14050 |
CCRIS 3439 |
HSDB 3029 |
Chloroquine (USP/INN) |
EINECS 200-191-2 |
{4-(7-chloro(4-quinolyl))aminopentyl}diethylamine |
Malaquin (*Diphosphate*) |
NSC 187208 |
BRN 0482809 |
Cloroquine |
Chloroquine USP:INN:BAN |
Chloroquine, 17 |
Chloroquine-d4 |
4,7-Dichloroquine |
Arechin (Salt/Mix) |
Delagil (Salt/Mix) |
Tanakan (Salt/Mix) |
1246815-14-4 |
RP-3377 |
Bemaphate (Salt/Mix) |
Resoquine (Salt/Mix) |
Spectrum_000132 |
Chloroquine + Proveblue |
Prestwick0_000548 |
Prestwick1_000548 |
Prestwick2_000548 |
Prestwick3_000548 |
Spectrum2_000127 |
Spectrum3_000341 |
Spectrum4_000279 |
Spectrum5_000707 |
(.+/-.)-Chloroquine |
1,4-Pentanediamine, N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl- |
Epitope ID:131785 |
MolMap_000009 |
SCHEMBL8933 |
Lopac0_000296 |
BSPBio_000595 |
BSPBio_002001 |
KBioGR_000778 |
KBioSS_000592 |
DivK1c_000404 |
CU-01000012392-2 |
SPBio_000174 |
SPBio_002516 |
GNF-Pf-4216 |
BPBio1_000655 |
GTPL5535 |
DTXSID2040446 |
BDBM22985 |
KBio1_000404 |
KBio2_000592 |
KBio2_003160 |
KBio2_005728 |
KBio3_001221 |
NINDS_000404 |
HMS2090O03 |
ALBB-025694 |
HY-17589A |
s6999 |
SBB072644 |
AKOS015935106 |
CCG-204391 |
CS-W004760 |
DB00608 |
KH-0005 |
MCULE-3610827164 |
SB73098 |
SDCCGSBI-0050284.P005 |
IDI1_000404 |
SMP2_000034 |
NCGC00015256-02 |
NCGC00015256-03 |
NCGC00015256-04 |
NCGC00015256-05 |
NCGC00015256-06 |
NCGC00015256-07 |
NCGC00015256-08 |
NCGC00015256-09 |
NCGC00015256-10 |
NCGC00015256-13 |
NCGC00015256-17 |
NCGC00015256-28 |
NCGC00162120-01 |
NCI60_000894 |
SY086904 |
WLN: T66 BNJ EMY1&3N2&2 IG |
SBI-0050284.P004 |
AB00053436 |
CS-0021871 |
FT-0623612 |
ST45028748 |
C07625 |
D02366 |
MLS-0466768.0001 |
AB00053436-05 |
AB00053436_06 |
AB00053436_07 |
1, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- |
Q422438 |
BRD-A91699651-065-01-1 |
BRD-A91699651-316-06-7 |
n(sup4)-(7-chloro-4-quinolinyl)-n(sup1),4-pentanediamine |
N-(7-chloroquinolin-4-yl)-N,N-diethylpentane-1,4-diamine |
N4-(7-chloro-4-quinolyl)-N1,N1-diethyl-pentane-1,4-diamine |
Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)- |
N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine |
1,4-pentanediamine, N~4~-(7-chloro-4-quinolinyl)-N~1~,N~1~-diethyl-, phosphate (1:2) |
N(sup4)-(7-chloro-4-quinolinyl)-N(sup1),N(sup1)-diethyl-1,4-pentanediamine |
117399-83-4 |
Chloroquine; Chloroquine Sulphate; 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine |
Experimental Data
chloroquine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 39.2 | ug/mL | 675 | 711 | 5.33 | Unclear | FEMALES | 4788962 | |||||
| Mus musculus | 13.2 | ug/mL | 675 | 600 | -11.11 | Unclear | FEMALES | 4788962 | Inactive |
Experimental Data Visualization
chloroquine
Statistics Data
chloroquine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Mus musculus | 5.33 | 1 | 2 |
Statistics Data Visualization
chloroquine
