Compound Summary
Compound Information
carvedilol
Compound Name: | carvedilol |
Compound CID: | 2585 |
Synonyms: | carvedilol 72956-09-3 Coreg Dilatrend Eucardic More... |
Iupac Name: | 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol |
InChI: | InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3 |
InChIKey: | OGHNVEJMJSYVRP-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O |
Isomeric Smiles: | COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O |
Molecular Weight: | 406.5 |
Molecular Formula: | C24H26N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
carvedilol
Molecular Weight: | 406.5 |
Molecular Formula: | C24H26N2O4 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 10 |
Heavy Atom Count: | 30 |
Complexity: | 508 |
Synonyms
carvedilol
| carvedilol | carvedilol |
|---|---|
carvedilol |
72956-09-3 |
Coreg |
Dilatrend |
Eucardic |
Carvedilolum Latin |
BM 14190 |
Carvedilolum |
1-(9H-Carbazol-4-yloxy)-3-2-(2-methoxyphenoxy)ethylamino-2-propanol |
SKF 105517 |
BM-14190 |
1-(9H-carbazol-4-yloxy)-3-2-(2-methoxyphenoxy)ethylaminopropan-2-ol |
1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol |
DQ 2466 |
C24H26N2O4 |
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol |
CHEMBL723 |
DQ-2466 |
CHEBI:3441 |
3-(9H-carbazol-4-yloxy)-2-hydroxypropyl2-(2-methoxyphenoxy)ethylamine |
1-(9H-carbazol-4-yloxy)-3-{2-(2-methoxyphenoxy)ethylamino}propan-2-ol |
MFCD00864692 |
(R)-BM 14190 |
(S)-BM 14190 |
Kredex |
Querto |
BM 14.190 |
Coropress |
Artist |
Dibloc |
1-(9H-carbazol-4-yloxy)-3-(2-{2-(methyloxy)phenyloxy}ethyl)aminopropan-2-ol |
SMR000449280 |
Artist (TN) |
Coreg (TN) |
HSDB 7044 |
SR-01000759289 |
MFCD00869663 |
1-(9H-Carbazol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol |
(R)-1-(4-Carbazolyl)oxy-3-2-(2-methoxyphenoxy)ethylamino-2-propanol |
Carvedilol D5 |
C07AG02 |
EG-P042 |
Carvedilol - Bio-X |
BM14190 |
Carvedilol USAN:USP:INN:BAN:JAN |
SK&F-105517 |
Spectrum_001665 |
BM-14-190 |
BM-14.190 |
Spectrum2_001673 |
Spectrum3_001182 |
Spectrum4_000636 |
Spectrum5_001436 |
SCHEMBL22293 |
GTPL551 |
KBioGR_001252 |
KBioSS_002145 |
MLS000758299 |
MLS000759508 |
MLS001424092 |
MLS006011886 |
SPBio_001885 |
Carvedilol (JP17/USP/INN) |
DTXSID8022747 |
SCHEMBL10082334 |
SCHEMBL13287211 |
BDBM25759 |
KBio2_002145 |
KBio2_004713 |
KBio2_007281 |
KBio3_002323 |
HMS2051N03 |
HMS2089B09 |
HMS2093E12 |
HMS3261E15 |
HMS3269N11 |
HMS3393N03 |
HMS3413B14 |
HMS3655O14 |
HMS3677B14 |
HMS3715D15 |
HMS3750I15 |
HMS3884E12 |
Pharmakon1600-01504257 |
Carvedilol 1.0 mg/ml in Methanol |
((c)I)-Carvedilol-d4(ethyl-d4) |
AMY40801 |
BCP23386 |
HY-B0006 |
Tox21_500347 |
BBL029064 |
MFCD00869664 |
NSC758694 |
s1831 |
STK621453 |
AKOS005554967 |
Carvedilol, >=98% (HPLC), solid |
AC-1641 |
BCP9000493 |
CCG-100917 |
CCG-207952 |
CS-1194 |
DB01136 |
KS-1037 |
LP00347 |
MCULE-7944987271 |
NC00167 |
NSC 758694 |
NSC-758694 |
SB17441 |
SDCCGSBI-0206771.P002 |
SKF-105517 |
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+-)- |
NCGC00167832-01 |
NCGC00167832-02 |
NCGC00167832-03 |
NCGC00167832-04 |
NCGC00167832-19 |
NCGC00261032-01 |
BC164291 |
SY129821 |
SY283162 |
BCP0726000253 |
SBI-0206771.P001 |
AB0008431 |
DB-055704 |
DB-057556 |
DB-057557 |
FT-0603055 |
FT-0603057 |
FT-0652640 |
FT-0664397 |
SW197547-3 |
C06875 |
D00255 |
F19969 |
J10039 |
AB00639903-07 |
AB00639903-09 |
AB00639903_10 |
AB00639903_11 |
AB00639903_12 |
102641-EP2270011A1 |
102641-EP2272841A1 |
102641-EP2275420A1 |
102641-EP2298764A1 |
102641-EP2298765A1 |
102641-EP2301936A1 |
956C093 |
L001243 |
Q412534 |
Q-200801 |
SR-01000759289-5 |
SR-01000759289-6 |
SR-01000759289-9 |
BRD-A10977446-001-04-8 |
BRD-A10977446-001-05-5 |
BRD-A10977446-045-01-1 |
Z2786051695 |
Carvedilol, European Pharmacopoeia (EP) Reference Standard |
Ethyl 2-(9-(pyridin-4-ylmethyl)-9H-fluoren-9-yl)acetate |
Carvedilol, United States Pharmacopeia (USP) Reference Standard |
1-(9H-carbazol-4-yloxy)-3-2-(2-methoxy-phenoxy)-ethylamino-propan-2-ol |
Carvedilol, Pharmaceutical Secondary Standard; Certified Reference Material |
Carvedilol for system suitability, European Pharmacopoeia (EP) Reference Standard |
107741-96-8 |
Experimental Data
carvedilol
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 46.64 | 46.93 | 0.6113 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 46.24 | 47.82 | 3.419 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 16.85 | 16.94 | 0.5428 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.86 | 16.02 | 1.027 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
carvedilol
Statistics Data
carvedilol
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1.027 | 1 | 2 | |
| Drosophila melanogaster | 3.419 | 1 | 2 |
Statistics Data Visualization
carvedilol
