Compound Summary
Compound Information
j147
Compound Name: | j147 |
Compound CID: | 25229652 |
Synonyms: | j147 J-147 1146963-51-0 UNII-Z41H3C5BT9 Z41H3C5BT9 More... |
Iupac Name: | N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide |
InChI: | InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+ |
InChIKey: | HYMZAYGFKNNHDN-SSDVNMTOSA-N |
Canonical Smiles: | CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)N=CC2=CC(=CC=C2)OC)C |
Isomeric Smiles: | CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C |
Molecular Weight: | 350.3 |
Molecular Formula: | C18H17F3N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
j147
Molecular Weight: | 350.3 |
Molecular Formula: | C18H17F3N2O2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 25 |
Complexity: | 481 |
Synonyms
j147
| j147 | j147 |
|---|---|
j147 |
J-147 |
1146963-51-0 |
UNII-Z41H3C5BT9 |
Z41H3C5BT9 |
J 147 |
N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N-(3-methoxybenzylidene)acetohydrazide" |
N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N-(E)-(3-methoxyphenyl)methyleneacetohydrazide |
1807913-16-1 |
N-(2,4-DIMETHYLPHENYL)-2,2,2-TRIFLUORO-N-(1E)-(3-METHOXYPHENYL)METHYLIDENEACETOHYDRAZIDE |
N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-(E)-(3-methoxyphenyl)methylideneaminoacetamide |
Acetic acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide |
Acetic acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-(3-methoxyphenyl)methylenehydrazide |
CHEMBL2387144 |
SCHEMBL12995834 |
SCHEMBL21294999 |
2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-(3-methoxyphenyl)methylenehydrazide |
C18H17F3N2O2 |
N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N-((E)-(3-methoxyphenyl)methylideneamino)acetamide |
HMS3886O17 |
EX-A2235 |
3752AH |
MFCD25976644 |
s5269 |
AKOS024458485 |
ZINC214323435 |
CCG-268030 |
CS-3688 |
DB13957 |
AS-16718 |
HY-13779 |
EC-000.2544 |
A15953 |
A894156 |
(E)-N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N-(3-methoxybenzylidene)acetohydrazide |
2,2,2-Trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-(3-methoxyphenyl) methylenehydrazide |
N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-(3-methoxyphenyl)methylideneacetohydrazide |
Acetic acid, 2,2,2-trifluoro-, (2E)-1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide |
Experimental Data
j147
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 2 | umol/L | 39.35 | 44.4 | 12.8 | S | Canton-S & W1118 | 33550278 | Active | ||||
| Drosophila melanogaster | 0.1 | umol/L | 9.5 | S | w1118 | MALES | 29316249 | Active | |||||
| Drosophila melanogaster | 2 | umol/L | 12.5 | S | w1118 | MALES | 29316249 | Active |
Experimental Data Visualization
j147
Statistics Data
j147
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 12.8 | 2 | 3 |
Statistics Data Visualization
j147
