Compound Summary
Compound Information
IMS2186
Compound Name: | IMS2186 |
Compound CID: | 24987039 |
Synonyms: | IMS2186 1031206-36-6 IMS 2186 3-1-(3-Hydroxy-4-methoxyphenyl)-meth-(E)-ylidene-6-methyl-chroman-4-one SCHEMBL4732781 More... |
Iupac Name: | (3E)-3-[(3-hydroxy-4-methoxyphenyl)methylidene]-6-methylchromen-4-one |
InChI: | InChI=1S/C18H16O4/c1-11-3-5-16-14(7-11)18(20)13(10-22-16)8-12-4-6-17(21-2)15(19)9-12/h3-9,19H,10H2,1-2H3/b13-8+ |
InChIKey: | BZCADTHMZLYKAR-MDWZMJQESA-N |
Canonical Smiles: | CC1=CC2=C(C=C1)OCC(=CC3=CC(=C(C=C3)OC)O)C2=O |
Isomeric Smiles: | CC1=CC2=C(C=C1)OC/C(=C\C3=CC(=C(C=C3)OC)O)/C2=O |
Molecular Weight: | 296.3 |
Molecular Formula: | C18H16O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
IMS2186
Molecular Weight: | 296.3 |
Molecular Formula: | C18H16O4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 22 |
Complexity: | 444 |
Synonyms
IMS2186
| IMS2186 | IMS2186 |
|---|---|
IMS2186 |
1031206-36-6 |
IMS 2186 |
3-1-(3-Hydroxy-4-methoxyphenyl)-meth-(E)-ylidene-6-methyl-chroman-4-one |
SCHEMBL4732781 |
HMS3263I22 |
Tox21_501090 |
ZINC44018876 |
CCG-222394 |
LP01090 |
SDCCGSBI-0633787.P001 |
NCGC00261775-01 |
NCGC00386646-03 |
IMS2186, >=98% (HPLC), solid |
J-000877 |
(E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methylchroman-4-one |
(3E)-3-(3-hydroxy-4-methoxyphenyl)methylidene-6-methylchromen-4-one |
(3E)-2,3-Dihydro-3-(3-hydroxy-4-methoxyphenyl)methylene-6-methyl-4H-1-benzopyran-4-one |
Experimental Data
IMS2186
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100 | umol/L | 17.76 | 16.02 | -9.809 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 49.36 | 48.88 | -0.9693 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 45.82 | 41.22 | -10.04 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 16.58 | 15.71 | -5.201 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
IMS2186
Statistics Data
IMS2186
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.201 | 1 | 2 | |
| Drosophila melanogaster | -0.9693 | 1 | 2 |
Statistics Data Visualization
IMS2186
