Compound Summary
Compound Information
quinacrine
Compound Name: | quinacrine |
Compound CID: | 237 |
Synonyms: | quinacrine mepacrine atabrine 83-89-6 Acrinamine More... |
Iupac Name: | 4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine |
InChI: | InChI=1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26) |
InChIKey: | GPKJTRJOBQGKQK-UHFFFAOYSA-N |
Canonical Smiles: | CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC |
Isomeric Smiles: | CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC |
Molecular Weight: | 400 |
Molecular Formula: | C23H30ClN3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
quinacrine
Molecular Weight: | 400 |
Molecular Formula: | C23H30ClN3O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 28 |
Complexity: | 461 |
Synonyms
quinacrine
| quinacrine | quinacrine |
|---|---|
quinacrine |
mepacrine |
atabrine |
83-89-6 |
Acrinamine |
Acriquine |
Erion |
Antimalarina |
Haffkinine |
Quinactine |
Akrichin |
Italchine |
acrichine |
Mepacrinum |
Quinacrine hydrochloride |
Quinacrine, Mepacrine |
St 439 |
6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine |
Malaricida |
Methoquine |
Italchin |
Metochin |
Palacrin |
Palusan |
Pentilen |
Mecryl |
3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine |
2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine |
1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl- |
CHEMBL7568 |
H0C805XYDE |
Mepacrine hydrochloride |
CHEBI:8711 |
GNF-PF-5448 |
Quinacrine (hydrochloride,hydrate) |
Mepacrine (INN) |
chinacrin |
Acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy- |
MEPACRINE INN |
N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine |
4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine |
N~4~-(6-chloro-2-methoxyacridin-9-yl)-N~1~,N~1~-diethylpentane-1,4-diamine |
Atabrine hydrochloride dihydrate; Mepacrine hydrochloride |
Mepacrina |
Quinacrin |
Mepacrine INN:BAN |
Mepacrinum INN-Latin |
Mepacrina INN-Spanish |
N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine |
HSDB 3253 |
EINECS 201-508-7 |
UNII-H0C805XYDE |
Acirchine |
6-chloro-N-(5-(diethylamino)pentan-2-yl)-2-methoxyacridin-9-amine |
AI3-04467 |
CCRIS 3726 |
CCRIS 8633 |
6-CHLORO-N-5-(DIETHYLAMINO)PENTAN-2-YL-2-METHOXYACRIDIN-9-AMINE |
Acridine, 6-chloro-9-4-(diethylamino)-1-methylbutylamino-2-methoxy- |
Quinacrine,Mepacrine |
Atebrin (Salt/Mix) |
Atebrine (Salt/Mix) |
Spectrum_000929 |
rac Quinacrine-d10 |
QUINACRINE MI |
Prestwick0_000318 |
Prestwick1_000318 |
Prestwick2_000318 |
Prestwick3_000318 |
Spectrum2_000888 |
Spectrum3_000606 |
Spectrum4_000496 |
Spectrum5_001405 |
(.+/-.)-Quinacrine |
QUINACRINE HSDB |
QUINACRINE VANDF |
MEPACRINE WHO-DD |
Lopac0_000970 |
SCHEMBL19225 |
BSPBio_000316 |
BSPBio_002112 |
KBioGR_001011 |
KBioGR_002507 |
KBioSS_001409 |
KBioSS_002515 |
DivK1c_000101 |
SPBio_000676 |
SPBio_002535 |
BPBio1_000348 |
DTXSID7022627 |
GTPL10172 |
KBio1_000101 |
KBio2_001409 |
KBio2_002507 |
KBio2_003977 |
KBio2_005075 |
KBio2_006545 |
KBio2_007643 |
KBio3_001612 |
KBio3_002985 |
cMAP_000067 |
NINDS_000101 |
HMS2090L03 |
BBL028456 |
BDBM50015214 |
RP-866 (Dihydrochloride dihydrate) |
SN-390 (Dihydrochloride dihydrate) |
STL061087 |
AKOS000541535 |
AKOS016340229 |
CCG-205050 |
DB01103 |
MS-1557 |
SDCCGSBI-0050943.P006 |
IDI1_000101 |
N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine |
NCGC00015874-02 |
NCGC00015874-03 |
NCGC00015874-04 |
NCGC00015874-08 |
NCGC00015874-12 |
NCGC00162300-01 |
NCI60_000926 |
SBI-0050943.P004 |
AB00053540 |
FT-0674264 |
FT-0778222 |
C07339 |
D08179 |
EN300-246511 |
AB00053540-08 |
AB00053540-09 |
AB00053540_10 |
Q417208 |
BRD-A45889380-300-04-8 |
BRD-A45889380-336-03-4 |
Z31251611 |
2-Methoxy-6-chloro-9-diethylaminopent-2-ylaminoacridine |
6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-methylbutyl)amine |
N-(6-chloro-2-methoxy-acridin-9-yl)-N,N-diethyl-pentane-1,4-diamine" |
N-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine |
N4-(6-chloro-2-methoxy-acridin-9-yl)-N1,N1-diethyl-pentane-1,4-diamine |
N4-(6-chloro-2-methoxyacridin-9-yl)-N1,N1-diethylpentane-1,4-diamine |
N-(6-Chloro-2-methoxy-acridin-9-yl)-N,N-diethyl-pentane-1,4-diamine dihydrochloride |
N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine (Mepacrine) |
N~4~-6-chloro-2-(methyloxy)acridin-9-yl-N~1~,N~1~-diethylpentane-1,4-diamine |
65960-39-6 |
N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine ; (mepacrine) |
Experimental Data
quinacrine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 7.5 | mM | 13 | 16 | 23 | Unclear | N2 | 27810360 | |||||
| Caenorhabditis elegans | 7.5 | mM | 13.11 | 15.51 | 18.3 | 17 | 19 | 11.76 | S | N2 | 27810360 | Active |
Experimental Data Visualization
quinacrine
Statistics Data
quinacrine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 23 | 11.76 | 1 | 2 |
Statistics Data Visualization
quinacrine
