Compound Summary
Compound Information
CEFAZOLIN SODIUM
Compound Name: | CEFAZOLIN SODIUM |
Compound CID: | 23675322 |
Synonyms: | CEFAZOLIN SODIUM Cefazolin sodium salt Cefazoline sodium 27164-46-1 Ancef More... |
Iupac Name: | sodium;(6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
InChI: | InChI=1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1 |
InChIKey: | FLKYBGKDCCEQQM-WYUVZMMLSA-M |
Canonical Smiles: | CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)[O-].[Na+] |
Isomeric Smiles: | CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)[O-].[Na+] |
Molecular Weight: | 476.5 |
Molecular Formula: | C14H13N8NaO4S3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
CEFAZOLIN SODIUM
Molecular Weight: | 476.5 |
Molecular Formula: | C14H13N8NaO4S3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 12 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 30 |
Complexity: | 746 |
Synonyms
CEFAZOLIN SODIUM
| CEFAZOLIN SODIUM | CEFAZOLIN SODIUM |
|---|---|
CEFAZOLIN SODIUM |
Cefazolin sodium salt |
Cefazoline sodium |
27164-46-1 |
Ancef |
Sodium cephazolin |
Kefzol |
Sodium cefazolin |
Zolicef |
Cephazolin Sodium |
Cefazil |
Totacef |
Cefazolin (sodium) |
Monosodium cefazolin |
CEFAZOLIN AND DEXTROSE |
Cefazina |
Firmacef |
Liviclina |
Atirin |
SK&F 41558 |
CHEBI:3483 |
UNII-P380M0454Z |
MLS000028706 |
MFCD00056883 |
P380M0454Z |
Biazolina |
Cefamedin |
Gramaxin |
SMR000058708 |
SKF 41558 |
Sodium CEZ |
Cefabiozim |
Cefalomicina |
Cefacidal |
Lampocef |
Neofazol |
Zolisint |
Recef |
Zolin |
Bor-Cefazol |
CEZ sodium |
Sodium (6R,7R)-7-(2-(1H-tetrazol-1-yl)acetamido)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
C14H13N8NaO4S3 |
Lilly 46083 |
ANCEF IN PLASTIC CONTAINER |
Cefazolin sodium USAN:USP:JAN |
sodium;(6R,7R)-3-(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl-8-oxo-7-2-(tetrazol-1-yl)acetylamino-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
Prestwick_975 |
EINECS 248-278-4 |
Ancef (TN) |
NSC 291561 |
NSC-291561 |
Opera_ID_1323 |
ANCEF IN DEXTROSE 5% IN PLASTIC CONTAINER |
SCHEMBL40735 |
SPECTRUM1500164 |
Cefazolin sodium (JP17/USP) |
Sodium CEZ; SKF-41558 |
CHEMBL1200523 |
HMS500A16 |
ANCEF IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER |
DTXSID901015786 |
HMS1570C14 |
HMS1920K07 |
HMS2091A10 |
HMS2097C14 |
HMS2230I22 |
HMS3260H10 |
HMS3714C14 |
HY-B1078 |
Tox21_500274 |
BDBM50247885 |
CCG-40011 |
s4595 |
AKOS015895533 |
CS-4634 |
LP00274 |
MCULE-2075772357 |
Cefazolin sodium salt, 89.1-110.1% |
NCGC00093731-01 |
NCGC00260959-01 |
AC-13166 |
AC-31729 |
AS-12230 |
Sodium (6R,7R)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate |
ST024775 |
EU-0100274 |
C 5020 |
C-2465 |
C08098 |
D00905 |
Cefazolin sodium 100 microg/mL in Acetonitrile/Water |
Q27106104 |
Cefazolin sodium salt, Antibiotic for Culture Media Use Only |
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)amino)-, (6R-trans)-, sodium salt |
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)amino)-, monosodium salt (6R-trans)- |
5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-8-oxo-7-2-(1H-tetrazol-1-yl)acetylamino-,(6R,7R)-,sodium |
Monosodium (6R,7R)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate |
sodium (6R,7R)-3-{(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl}-8-oxo-7-(1H-tetrazol-1-ylacetyl)amino-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
sodium (6R,7R)-7-(2-(1H-tetrazol-1-yl)acetamido)-3-((5-methyl-1,3,4-thiadiazol-2-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
Sodium (6R-trans)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(1H-tetrazol-1-ylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate |
sodium 3-{(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl}-7beta-(1H-tetrazol-1-ylacetyl)amino-3,4-didehydrocepham-4-carboxylate |
sodium 7beta-(1H-tetrazol-1-yl)acetamido-3-(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl-3-cephem-4-carboxylate |
sodium 7beta-2-(1H-tetrazol-1-yl)-acetamido-3-(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl-3-cephem-4-carboxylate |
sodium 7beta-2-(1H-tetrazol-1-yl)acetamido-3-(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl-3-cephem-4-carboxylate |
Experimental Data
CEFAZOLIN SODIUM
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -9 | NS | N2 | 24134630 | Inactive | ||||||
| Drosophila melanogaster | 200 | umol/L | 43.17 | 40.69 | -5.738 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.86 | 12.91 | -18.63 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 17.37 | 16.63 | -4.274 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 44.63 | 45.78 | 2.574 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
CEFAZOLIN SODIUM
Statistics Data
CEFAZOLIN SODIUM
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.274 | 2 | 3 | |
| Drosophila melanogaster | 2.574 | 1 | 2 |
Statistics Data Visualization
CEFAZOLIN SODIUM
