Compound Summary
Compound Information
Cyclophosphamide monohydrate
Compound Name: | Cyclophosphamide monohydrate |
Compound CID: | 22420 |
Synonyms: | Cyclophosphamide monohydrate 6055-19-2 Cyclophosphamide hydrate Cytoxan 2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate More... |
Iupac Name: | N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine;hydrate |
InChI: | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
InChIKey: | PWOQRKCAHTVFLB-UHFFFAOYSA-N |
Canonical Smiles: | C1CNP(=O)(OC1)N(CCCl)CCCl.O |
Isomeric Smiles: | C1CNP(=O)(OC1)N(CCCl)CCCl.O |
Molecular Weight: | 279.1 |
Molecular Formula: | C7H17Cl2N2O3P |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Cyclophosphamide monohydrate
Molecular Weight: | 279.1 |
Molecular Formula: | C7H17Cl2N2O3P |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 15 |
Complexity: | 212 |
Synonyms
Cyclophosphamide monohydrate
| Cyclophosphamide monohydrate | Cyclophosphamide monohydrate |
|---|---|
Cyclophosphamide monohydrate |
6055-19-2 |
Cyclophosphamide hydrate |
Cytoxan |
2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate |
Cyclophosphamide (hydrate) |
6055-19-2 (hydrate) |
MFCD00149395 |
MLS001306483 |
CHEBI:4026 |
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridine monohydrate |
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate |
2-(Bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane 2-oxide monohydrate |
2-(Di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydrate |
(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 monohydrate |
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxaphosphorin-2-amine, 2-oxide monohydrate |
N,N-Bis(beta-chloroethyl)-N,O-trimethylenephosphoric acid ester diamide monohydrate |
Endoxon |
Cytoxan (TN) |
DSSTox_CID_4888 |
NSC-26271 |
(+-)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate |
2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate |
2-Bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide monohydrate |
DSSTox_RID_77569 |
Endoxan monohydrate |
C7H17Cl2N2O3P |
DSSTox_GSID_24888 |
Ciclophosphamide hydrat |
2-Bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide |
Cytoxan hydrate |
N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide hydrate |
Cyclophosphamide (hydrated) |
2-bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate |
CAS-6055-19-2 |
CCRIS 7469 |
Cytoxan (Lyophilized) |
NCGC00015209-05 |
Revimmune |
N,N-bis(2-chloroethyl)-2-oxo-1,3,2?^{5}-oxazaphosphinan-2-amine;hydrate |
Prestwick_137 |
Neosar (TN) |
2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate |
Cyclophosphamide USP:INN:BAN:JAN |
Cyclophosphamide,(S) |
Cyclophosphamide (USP) |
N,N-Bis(beta-chloroethyl)-N,O-propylenephosphoric acid ester amide monohydrate" |
N,N-Bis(beta-cloraethyl) N-O-propylenphosphorildiamid monohydratum Romanian |
SCHEMBL6071 |
Cyclic N,O-propylene ester of N,N-bis(2-chloroethyl)phosphorodiamidic acid monohydrate |
N,N-Di(2-chloroethyl)amino-N,O-propylene phosphoric acid ester diamide monohydrate |
SPECTRUM1500213 |
CHEMBL1200796 |
DTXSID6024888 |
Cyclophosphamide hydrate (JP17) |
HMS500M08 |
HMS1920C04 |
HMS2091I12 |
HMS2234I13 |
HMS3259P15 |
HMS3370O11 |
BCP22663 |
Tox21_110100 |
Tox21_201503 |
Tox21_300529 |
CCG-40013 |
HY-17420A |
N,N-Bis(beta-cloraethyl) N-O-propylenphosphorildiamid monohydratum |
s2057 |
AKOS009144593 |
N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine;hydrate |
Tox21_110100_1 |
AC-1741 |
BCP9000569 |
CS-5005 |
NC00662 |
2H-1,3,2-Oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide, monohydrate |
N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate |
Cyclophosphamide monohydrate, ISOPAC(R) |
NCGC00015209-11 |
NCGC00091741-01 |
NCGC00091741-04 |
NCGC00094636-01 |
NCGC00094636-02 |
NCGC00094636-03 |
NCGC00094636-04 |
NCGC00180900-01 |
NCGC00254543-01 |
NCGC00259054-01 |
2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate, (+-) |
AS-13677 |
BP-12392 |
Cyclophosphamide monohydrate, bulk package |
H538 |
SMR000718805 |
BCP0726000113 |
AB0006982 |
DB-053644 |
B-518 |
FT-0624277 |
SW199628-3 |
EN300-52512 |
C06933 |
D00287 |
J10095 |
29545-EP2308812A2 |
29545-EP2311842A2 |
Cyclophosphamide monohydrate, analytical standard |
055C192 |
SR-01000075737-4 |
Q27106287 |
UNII-8N3DW7272P component PWOQRKCAHTVFLB-UQKRIMTDSA-N |
Cyclophosphamide, European Pharmacopoeia (EP) Reference Standard |
Cyclophosphamide, United States Pharmacopeia (USP) Reference Standard |
Cyclophosphamide, Pharmaceutical Secondary Standard; Certified Reference Material |
N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide--water (1/1) |
Experimental Data
Cyclophosphamide monohydrate
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 0 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Cyclophosphamide monohydrate
Statistics Data
Cyclophosphamide monohydrate
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0 | 1 | 1 |
Statistics Data Visualization
Cyclophosphamide monohydrate
