Compound Summary
Compound Information
Epitalon
Compound Name: | Epitalon |
Compound CID: | 219042 |
Synonyms: | Epitalon Epithalon 307297-39-8 Epithalone UNII-O65P17785G More... |
Iupac Name: | (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
InChI: | InChI=1S/C14H22N4O9/c1-6(15)12(25)17-7(2-3-9(19)20)14(27)18-8(4-10(21)22)13(26)16-5-11(23)24/h6-8H,2-5,15H2,1H3,(H,16,26)(H,17,25)(H,18,27)(H,19,20)(H,21,22)(H,23,24)/t6-,7-,8-/m0/s1 |
InChIKey: | HGHOBRRUMWJWCU-FXQIFTODSA-N |
Canonical Smiles: | CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N |
Isomeric Smiles: | C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O)N |
Molecular Weight: | 390.35 |
Molecular Formula: | C14H22N4O9 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Epitalon
Molecular Weight: | 390.35 |
Molecular Formula: | C14H22N4O9 |
Hydrogen Bond Donor Count: | 7 |
Hydrogen Bond Acceptor Count: | 10 |
Rotatable Bond Count: | 12 |
Heavy Atom Count: | 27 |
Complexity: | 607 |
Synonyms
Epitalon
| Epitalon | Epitalon |
|---|---|
Epitalon |
Epithalon |
307297-39-8 |
Epithalone |
UNII-O65P17785G |
Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl- |
O65P17785G |
64082-79-7 |
(4S)-4-(2S)-2-aminopropanoylamino-5-(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-ylamino-5-oxopentanoic acid |
Epithalamin |
Epithalamine |
Ala-Glu-Asp-Gly |
AE-0 peptide |
L-Alanyl-L-&Alpha |
alanyl-glutamyl-aspartyl-glycine |
SCHEMBL5685928 |
DTXSID80952957 |
BCP13981 |
HY-P1149 |
ZINC3966198 |
AC-33517 |
CS-0028299 |
Glycine, L-alanyl-L-a-glutamyl-L-a-aspartyl- |
A14399 |
A876104 |
Glycine, L-alanyl-L-a-glutamyl-L-a-aspartyl- Acetate |
Q27285389 |
4-(2-Amino-1-hydroxypropylidene)amino-5-({3-carboxy-1-(carboxymethyl)imino-1-hydroxypropan-2-yl}imino)-5-hydroxypentanoic acid |
Experimental Data
Epitalon
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 0.000001 | % | 32.39 | 33.43 | 0.03 | Unclear | Canton-S | FEMALES | 11087911 | ||||
| Drosophila melanogaster | 0.0000001 | % | 31.42 | 35.13 | 0.12 | S | Canton-S | FEMALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.000005 | % | 33.9 | 37.74 | 0.11 | S | Canton-S | MALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.000001 | % | 29.99 | 33.8 | 0.13 | S | Canton-S | MALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.000000001 | % | 35.41 | 41.3 | 0.17 | S | Canton-S | MALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.000005 | % | 36.87 | 38.04 | 0.03 | Unclear | Canton-S | FEMALES | 11087911 | ||||
| Drosophila melanogaster | 0.00000001 | % | 32.55 | 36.47 | 0.12 | S | Canton-S | MALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.0000001 | % | 31.44 | 34.85 | 0.11 | S | Canton-S | MALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.00000001 | % | 31.22 | 35.41 | 0.13 | S | Canton-S | FEMALES | 11087911 | Active | |||
| Drosophila melanogaster | 0.000000001 | % | 32.07 | 34.36 | 0.07 | Unclear | Canton-S | FEMALES | 11087911 | ||||
| Drosophila melanogaster | 25 | 29 | 16 | S | C3H/Sn | FEMALES | 9701766 | Active | |||||
| Mus musculus | 487 | 640 | 31 | S | 9701766 | Active | |||||||
| Mus musculus | 564 | 627 | 11 | S | C3H/Sn | FEMALES | 9701766 | Active | |||||
| Rattus norvegicus | 681 | 852 | 25 | S | Outbred | 9701766 | Active |
Experimental Data Visualization
Epitalon
Statistics Data
Epitalon
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 16 | 2 | 11 | |
| Mus musculus | 31 | 1 | 2 | |
| Rattus norvegicus | 25 | 1 | 1 |
Statistics Data Visualization
Epitalon
