Compound Summary
Compound Information
amlexanox
Compound Name: | amlexanox |
Compound CID: | 2161 |
Synonyms: | amlexanox 68302-57-8 Amoxanox Aphthasol 2-Amino-7-isopropyl-5-oxo-5H-chromeno2,3-bpyridine-3-carboxylic acid More... |
Iupac Name: | 2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid |
InChI: | InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) |
InChIKey: | SGRYPYWGNKJSDL-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N |
Isomeric Smiles: | CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N |
Molecular Weight: | 298.29 |
Molecular Formula: | C16H14N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
amlexanox
Molecular Weight: | 298.29 |
Molecular Formula: | C16H14N2O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 22 |
Complexity: | 467 |
Synonyms
amlexanox
| amlexanox | amlexanox |
|---|---|
amlexanox |
68302-57-8 |
Amoxanox |
Aphthasol |
2-Amino-7-isopropyl-5-oxo-5H-chromeno2,3-bpyridine-3-carboxylic acid |
Amlenanox |
Amlexanoxum Latin |
Amlexanoxo Spanish |
AA-673 |
Amlexanoxo |
Amlexanoxum |
CHX 3673 |
AA 673 |
CHX-3673 |
2-amino-5-oxo-7-propan-2-ylchromeno2,3-bpyridine-3-carboxylic acid |
2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno2,3-bpyridine-3-carboxylic acid |
UNII-BRL1C2459K |
2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid |
AA673;Amoxanox;CHX3673 |
BRL1C2459K |
CHEBI:31205 |
2-Amino-7-isopropyl-5-oxo-5H-chromeno-2,3-bpyridine-3-carboxylic acid |
2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno2,3-bpyridine-3-carboxylic acid |
MFCD00864790 |
2-Amino-7-(1-methylethyl)-5-oxo-5H-1benzopyrano2,3-bpyridine-3-carboxylic acid |
NCGC00167472-01 |
Elics |
Amlexanox USAN:INN:JAN |
DSSTox_CID_2595 |
5H-(1)Benzopyrano(2,3-b)pyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo- |
DSSTox_RID_76651 |
DSSTox_GSID_22595 |
Aptheal |
Apthera |
OraRinse |
2-Amino-7-isopropyl-5-oxochromeno2,3-bpyridine-3-carboxylic Acid |
OraDisc A |
Aphthasol (TN) |
ANW |
SMR000466352 |
CAS-68302-57-8 |
CCRIS 2686 |
Solfa (TN) |
BRN 0556384 |
4wbo |
5H-1Benzopyrano2,3-bpyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo- |
Amlexanox USAN:INN:BAN:JAN |
Amlexanox- Bio-X |
AA-673(Amlexanox) |
CHEMBL1096 |
SCHEMBL29642 |
ZINC928 |
MLS000759466 |
MLS001424059 |
MLS006010129 |
BIDD:GT0709 |
US10214536, Amlexanox |
GTPL7113 |
Amlexanox (JP17/USAN/INN) |
Amlexanox, >=98% (HPLC) |
DTXSID2022595 |
CHX3673 |
AA673 |
BDBM357857 |
HMS2051F13 |
HMS2235M08 |
HMS3393F13 |
HMS3715B14 |
ACN-S001255 |
BCP28222 |
HY-B0713 |
Tox21_112476 |
CA0192 |
s3648 |
AKOS015900498 |
Tox21_112476_1 |
AC-1192 |
CCG-100953 |
DB01025 |
DS-1396 |
NC00203 |
NCGC00167472-02 |
NCGC00167472-03 |
NCGC00167472-14 |
BA164161 |
H834 |
AB0013295 |
FT-0641176 |
D01828 |
J90008 |
AB00639947-06 |
AB00639947_08 |
302A578 |
A836094 |
L001037 |
Q695611 |
Amlexanox, United States Pharmacopeia (USP) Reference Standard |
2-Amino-7-isopropyl-5-oxo-5H-1benzopyrano2,3-b pyridine-3-carboxylic acid |
2-amino-7-isopropyl-5-oxo-chromeno2,3-bpyridine-3-carboxylic acid;Amlexanox |
Experimental Data
amlexanox
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100 | umol/L | 15.86 | 16.72 | 5.39 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 43.17 | 43.39 | 0.5188 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 44.63 | 45.67 | 2.327 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 17.37 | 16.99 | -2.205 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
amlexanox
Statistics Data
amlexanox
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.39 | 1 | 2 | |
| Drosophila melanogaster | 2.327 | 1 | 2 |
Statistics Data Visualization
amlexanox
