Compound Summary
Compound Information
Mexiletine hydrochloride
Compound Name: | Mexiletine hydrochloride |
Compound CID: | 21467 |
Synonyms: | Mexiletine hydrochloride 5370-01-4 Mexiletine HCL Mexitil Mexiletene hydrochloride More... |
Iupac Name: | 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride |
InChI: | InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H |
InChIKey: | NFEIBWMZVIVJLQ-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(C(=CC=C1)C)OCC(C)N.Cl |
Isomeric Smiles: | CC1=C(C(=CC=C1)C)OCC(C)N.Cl |
Molecular Weight: | 215.72 |
Molecular Formula: | C11H18ClNO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Mexiletine hydrochloride
Molecular Weight: | 215.72 |
Molecular Formula: | C11H18ClNO |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 14 |
Complexity: | 139 |
Synonyms
Mexiletine hydrochloride
| Mexiletine hydrochloride | Mexiletine hydrochloride |
|---|---|
Mexiletine hydrochloride |
5370-01-4 |
Mexiletine HCL |
Mexitil |
Mexiletene hydrochloride |
Mexiletine (hydrochloride) |
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride |
1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride |
2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride |
KOE-1173 (hydrochloride) |
Ko 1173 Cl |
KO1173 |
MFCD00216024 |
1-Methyl-2-(2,6-xylyloxy)ethylammonium chloride |
1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride |
2-(2-aminopropoxy)-1,3-dimethylbenzene hydrochloride |
Ethylamine, 1-methyl-2-(2,6-xylyloxy)-, hydrochloride |
NCGC00094121-01 |
DSSTox_CID_25783 |
DSSTox_RID_81125 |
DSSTox_GSID_45783 |
1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride |
1-(2,6-Dimethylphenoxy)-2-aminopropane hydrochloride |
CHEBI:6917 |
(+-)-1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride |
SMR000326711 |
CAS-5370-01-4 |
1-(2,6-Xylyloxy)-2-aminopropane |
1-(2,6-dimethylphenoxy)prop-2-ylamine, chloride |
SR-01000075986 |
NCGC00015659-06 |
KO 1173 |
(2S)-1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride |
Mexiletine, HCl |
UNII-606D60IS38 |
Prestwick_666 |
EINECS 226-362-1 |
Mexitil (TN) |
KO-1173 |
606D60IS38 |
1-(2,6-Xylyloxy)-2-aminopropane hydrochloride |
SCHEMBL42226 |
MLS001056756 |
MLS002222239 |
MLS002548872 |
SPECTRUM1503929 |
1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride |
MEXILITENE HYDROCHLORIDE |
Mexiletine hydrochloride, powder |
CHEMBL1200606 |
DTXSID2045783 |
KO-1173-Cl |
HMS1568B04 |
KO-1173 CL |
Pharmakon1600-01503929 |
2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride, (+-)- |
BCP28602 |
EBD30089 |
HY-A0093 |
Tox21_111249 |
Tox21_500784 |
NSC758639 |
s4225 |
SBB003392 |
Mexiletine hydrochloride (JP17/USP) |
AKOS009139802 |
Tox21_111249_1 |
Tox21_111249_2 |
AC-4260 |
AC-8240 |
CCG-213246 |
LP00784 |
MCULE-4507699259 |
NC00682 |
NSC 758639 |
NSC-758639 |
VA11290 |
NCGC00015659-14 |
NCGC00094121-02 |
NCGC00094121-03 |
NCGC00094121-04 |
NCGC00261469-01 |
5370-01-4 (HCl) |
AS-13790 |
Mexiletine hydrochloride USAN:USP:JAN |
ST083488 |
1-(2,6-Dimethylphenoxy)-2-propanamine HCl |
EU-0100784 |
FT-0672397 |
FT-0672398 |
M2040 |
SW196821-3 |
V0364 |
EN300-53944 |
D00639 |
J10321 |
M 2727 |
370M014 |
A829739 |
Mexiletine HCl;KO-1173; KO 1173; KO1173 |
SR-01000075986-1 |
SR-01000075986-6 |
W-105713 |
Q27107357 |
1-(2,6-dimethylphenoxy)-2-amino-propane hydrochloride; |
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride, 97% |
Mexiletine hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Mexiletine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
Mexiletine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Mexiletine hydrochloride
Statistics Data
Mexiletine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5 | 1 | 1 |
Statistics Data Visualization
Mexiletine hydrochloride
