Compound Summary
Compound Information
21102-95-4
Compound Name: | 21102-95-4 |
Compound CID: | 210172 |
Synonyms: | 21102-95-4 BMY 7378 dihydrochloride BMY 7378 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro4.5decane-7,9-dione dihydrochloride BMY7378 More... |
Iupac Name: | 8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione;dihydrochloride |
InChI: | InChI=1S/C22H31N3O3.2ClH/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22;;/h2-3,6-7H,4-5,8-17H2,1H3;2*1H |
InChIKey: | NIBOMXUDFLRHRV-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O.Cl.Cl |
Isomeric Smiles: | COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O.Cl.Cl |
Molecular Weight: | 458.4 |
Molecular Formula: | C22H33Cl2N3O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
21102-95-4
Molecular Weight: | 458.4 |
Molecular Formula: | C22H33Cl2N3O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 30 |
Complexity: | 547 |
Synonyms
21102-95-4
| 21102-95-4 | 21102-95-4 |
|---|---|
21102-95-4 |
BMY 7378 dihydrochloride |
BMY 7378 |
8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro4.5decane-7,9-dione dihydrochloride |
BMY7378 |
UNII-KC07KV8T5O |
BMY7378 HCl |
KC07KV8T5O |
CHEMBL543741 |
1,1-Cyclopentanediacetimide, N-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-, dihydrochloride |
8-2-4-(2-methoxyphenyl)piperazin-1-ylethyl-8-azaspiro4.5decane-7,9-dione;dihydrochloride |
C17H17ClN4 |
8-2-4-(2-Methoxyphenyl)-1-piperazinylethyl-8-azaspiro4.5decane-7,9-dione dihydrochloride |
SR-01000075542 |
BMY7378 dihydrochloride |
azaspiro4.5decane-7,9-dione dihydrochloride |
N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride |
SCHEMBL987183 |
BMY 7378 2HCl |
C22H31N3O3.2HCl |
C22H33Cl2N3O3 |
AOB6861 |
DTXSID10175334 |
BCP02522 |
EX-A2035 |
WAA10295 |
Tox21_500206 |
MFCD00153771 |
s2691 |
AKOS015999114 |
CCG-221510 |
LP00206 |
MG-0114 |
NCGC00093679-01 |
NCGC00260891-01 |
AC-26868 |
DA-35011 |
B-134 |
EU-0100206 |
FT-0710084 |
SW219365-1 |
X7600 |
A25032 |
C74006 |
8-2-4-(2-Methoxyphenyl)-1-piperazinylethyl- |
BMY 7378 dihydrochloride, >=98% (HPLC), solid |
J-013847 |
SR-01000075542-1 |
SR-01000075542-3 |
Q27894467 |
8-Chloro-11-(1-piperazinyl)-5H-dibe nzob,e1,4diazepine |
8-2-4-(2-Methoxyphenyl)-1-piperazinylethyl-8-azaspiro4.5decane-7,9-dione 2HCl |
8-2-4-(2-Methoxyphenyl)-1-piperazinylethyl-8-azaspiro4.5decane-7,9-dione dihydrochloride |
8-2-4-(2-Methoxyphenyl)-1-piperazinylethyl-8-azaspiro4.5decane-7,9-dione hydrochloride |
8-2-4-(methoxyphenyl)-1-piperazin ylethyl-8-azaspiro4.5decane-7,9-dione dihydrochloride |
8-2-4-(methoxyphenyl)-1-piperazinylethyl-8- azaspiro4.5decane-7,9-dione dihydrochloride;BMY 7378 |
8-2-4-(methoxyphenyl)-1-piperazinylethyl-8-azaspiro4.5decane-7,9-dione dihydrochloride |
8-Azaspiro4.5decane-7,9-dione, 8-2-4-(2-methoxyphenyl)-1-piperazinylethyl-, hydrochloride |
Experimental Data
21102-95-4
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 2 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
21102-95-4
Statistics Data
21102-95-4
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2 | 1 | 1 |
Statistics Data Visualization
21102-95-4
