Compound Summary
Compound Information
Tyrphostin A25
Compound Name: | Tyrphostin A25 |
Compound CID: | 2061 |
Synonyms: | Tyrphostin A25 Tyrphostin 25 118409-58-8 Tyrphostin-25 2-(3,4,5-trihydroxyphenyl)methylidenepropanedinitrile More... |
Iupac Name: | 2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile |
InChI: | InChI=1S/C10H6N2O3/c11-4-7(5-12)1-6-2-8(13)10(15)9(14)3-6/h1-3,13-15H |
InChIKey: | YZOFLYUAQDJWKV-UHFFFAOYSA-N |
Canonical Smiles: | C1=C(C=C(C(=C1O)O)O)C=C(C#N)C#N |
Isomeric Smiles: | C1=C(C=C(C(=C1O)O)O)C=C(C#N)C#N |
Molecular Weight: | 202.17 |
Molecular Formula: | C10H6N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin A25
Molecular Weight: | 202.17 |
Molecular Formula: | C10H6N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 15 |
Complexity: | 329 |
Synonyms
Tyrphostin A25
| Tyrphostin A25 | Tyrphostin A25 |
|---|---|
Tyrphostin A25 |
Tyrphostin 25 |
118409-58-8 |
Tyrphostin-25 |
2-(3,4,5-trihydroxyphenyl)methylidenepropanedinitrile |
Tyrphostin A 25 |
2-(3,4,5-Trihydroxybenzylidene)malononitrile |
alpha-Cyano-(3,4,5-trihydroxy)cinnamonitrile |
AG-82 |
NSC676484 |
Propanedinitrile, 2-(3,4,5-trihydroxyphenyl)methylene- |
NCGC00016046-02 |
AG 82; RG50875; RG-50875;RG 50875;Tyrphostin A 25; Tyrphostin AG 82 |
(3,4,5-Trihydroxybenzylidene)-malononitrile |
NSC 676484 |
AG 82 |
Tyrphostin A-25 |
((3,4,5-Trihydroxyphenyl)methylene)propanedinitrile |
Tyrophostin AG-82 |
(4,5-Trihydroxybenzylidene)malononitrile |
TYRPHOSTINA25 |
BiomolKI_000012 |
Lopac-T-7290 |
BiomolKI2_000022 |
DSSTox_CID_25216 |
DSSTox_RID_80755 |
DSSTox_GSID_45216 |
Lopac0_001190 |
158129-55-6 |
SCHEMBL239879 |
BDBM4341 |
BMK1-B12 |
CHEMBL310798 |
DTXSID4045216 |
Propanedinitrile, ((3,4,5-trihydroxyphenyl)methylene)- |
CHEBI:92063 |
ZINC57523 |
Propanedinitrile,2-(3,4,5-trihydroxyphenyl)methylene- |
Tox21_110288 |
2089AH |
HSCI1_000114 |
MCK101002 |
MFCD00133900 |
CCG-100616 |
NSC-676484 |
NCGC00016046-01 |
NCGC00016046-03 |
NCGC00016046-04 |
NCGC00016046-05 |
NCGC00094443-01 |
NCGC00094443-02 |
NCGC00094443-03 |
benzylidenemalononitrile (BMN) deriv. 25 |
CAS-118409-58-8 |
EU-0101190 |
FT-0675717 |
EC-000.2087 |
T 7290 |
SR-01000076172 |
AG 82 - CAS 118409-58-8 |
J-003745 |
SR-01000076172-1 |
2-(3,4,5-trihydroxyphenyl)methylenepropanedinitrile |
BRD-K03670461-001-03-8 |
Q27163858 |
Experimental Data
Tyrphostin A25
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 13 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin A25
Statistics Data
Tyrphostin A25
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 13 | 1 | 1 |
Statistics Data Visualization
Tyrphostin A25
