Compound Summary
Compound Information
acetazolamide
Compound Name: | acetazolamide |
Compound CID: | 1986 |
Synonyms: | acetazolamide 59-66-5 Diamox N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide Acetazolamid More... |
Iupac Name: | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide |
InChI: | InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
InChIKey: | BZKPWHYZMXOIDC-UHFFFAOYSA-N |
Canonical Smiles: | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
Isomeric Smiles: | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
Molecular Weight: | 222.3 |
Molecular Formula: | C4H6N4O3S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
acetazolamide
Molecular Weight: | 222.3 |
Molecular Formula: | C4H6N4O3S2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 13 |
Complexity: | 297 |
Synonyms
acetazolamide
| acetazolamide | acetazolamide |
|---|---|
acetazolamide |
59-66-5 |
Diamox |
N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide |
Acetazolamid |
Acetamox |
Diacarb |
Glaupax |
Defiltran |
Nephramide |
Cidamex |
Diluran |
Edemox |
Dehydratin |
Diuramid |
Diutazol |
Duiramid |
Eumicton |
Natrionex |
Nephramid |
Phonurit |
Diakarb |
Donmox |
Fonurit |
Glupax |
Vetamox |
Didoc |
SK-acetazolamide |
Diuriwas |
5-Acetamido-1,3,4-thiadiazole-2-sulfonamide |
Acetazoleamide |
Acetozalamide |
Diureticum-holzinger |
Acetamidothiadiazolesulfonamide |
Acetazolamida |
Acetazolamidum |
4-Diamox |
Acetamide, N-5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl- |
Carbonic Anhydrase Inhibitor No. 6063 |
2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide |
N-5-(aminosulfonyl)-1,3,4-thiadiazol-2-ylacetamide |
C4H6N4O3S2 |
2-Acetamido-5-sulfonamido-1,3,4-thiadiazole |
Carbonic anhydrase inhibitor 6063 |
UNII-O3FX965V0I |
NSC 145177 |
1,3,4-Thiadiazole-2-sulfonamide, 5-acetamido- |
5-Acetamide-1,3,4-thiadiazole-2-sulfonamide |
CHEMBL20 |
MFCD00003105 |
Diamox (TN) |
N-(5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl)acetamide |
MLS000028435 |
O3FX965V0I |
CHEBI:27690 |
Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)- |
NSC-145177 |
CAS-59-66-5 |
N-5-(Aminosulfonyl)-1,3,4-thiadiozol-2-yl-Acetamide |
NCGC00015074-10 |
Acetazolamine |
Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)- |
Atenezol |
Glaumox |
SMR000058394 |
Diamox Sequels |
DSSTox_CID_2544 |
5-acetylamino-1,3,4-thiadiazole-2-sulfonamide |
DSSTox_RID_76621 |
DSSTox_GSID_22544 |
Acetazolamidum INN-Latin |
Acetazolamida INN-Spanish |
N-(5-Aminosulfonyl-1,3,4-thiadiazol-2-yl)acetamide |
N-5-(aminosulfonyl)-1,3,5-thiadiazol-2-ylacetamide |
CCRIS 5811 |
Acetazolamide (AAZ) |
HSDB 3002 |
SR-01000000065 |
EINECS 200-440-5 |
AI3-52458 |
Prestwick_4 |
1azm |
1yda |
1ydb |
1ydd |
1zsb |
2xtk |
3czv |
3ucj |
Acetazolamide, 5 |
Acetazolamide USP:INN:BAN:JAN |
Acerazolamide, AAZ |
Acetazolamide, AAZ |
Acetazolamide, AZA |
Acetazolamide, AZM |
ACMC-20gwkd |
Spectrum_000018 |
1jd0 |
2h4n |
2uy4 |
3dc3 |
3hs4 |
3ml5 |
4g0c |
Opera_ID_288 |
AZA2 |
Prestwick0_000003 |
Prestwick1_000003 |
Prestwick2_000003 |
Prestwick3_000003 |
Spectrum2_000082 |
Spectrum3_000284 |
Spectrum4_000139 |
Spectrum5_000738 |
Lopac-A-6011 |
A 6011 |
Lopac0_000039 |
SCHEMBL23219 |
BSPBio_000005 |
BSPBio_001788 |
KBioGR_000558 |
KBioSS_000358 |
MLS001148438 |
BIDD:GT0643 |
DivK1c_000017 |
SPECTRUM1500102 |
N-(5-Sulfamoyl-1,3,4thiadiazol-2-yl)-acetamide |
SPBio_000004 |
SPBio_001926 |
BPBio1_000007 |
GTPL6792 |
(non-d)Acetazolamide-13C2-d3 |
Acetazolamide, >=99%, powder |
DTXSID7022544 |
SCHEMBL11049053 |
BDBM10880 |
BZKPWHYZMXOIDC-UHFFFAOYSA- |
HMS500A19 |
KBio1_000017 |
KBio2_000358 |
KBio2_002926 |
KBio2_005494 |
KBio3_001288 |
Acetazolamide (JP17/USP/INN) |
AMY3289 |
Acetazolamide, analytical standard |
NINDS_000017 |
HMS1568A07 |
HMS1920A05 |
HMS2091G05 |
HMS2095A07 |
HMS2232G23 |
HMS3259I13 |
HMS3260G19 |
HMS3370P01 |
HMS3712A07 |
HMS3744A21 |
Pharmakon1600-01500102 |
WLN: T5NN DSJ CSZW EMV1 |
ALBB-023617 |
BCP29616 |
EBD55026 |
HY-B0782 |
ZINC3813042 |
Tox21_110078 |
Tox21_201559 |
Tox21_302773 |
Tox21_500039 |
CCG-38900 |
NSC145177 |
NSC755854 |
s4506 |
SBB056640 |
AKOS000715163 |
Tox21_110078_1 |
CS-3568 |
DB00819 |
LP00039 |
MCULE-4029778803 |
NC00491 |
NSC-755854 |
SDCCGSBI-0050028.P005 |
Acetazolamide Related Compound (5-acetamido-1,3,4-thiadiazole-2-sulfonic acid) |
IDI1_000017 |
NCGC00015074-01 |
NCGC00015074-02 |
NCGC00015074-03 |
NCGC00015074-04 |
NCGC00015074-05 |
NCGC00015074-06 |
NCGC00015074-07 |
NCGC00015074-08 |
NCGC00015074-09 |
NCGC00015074-11 |
NCGC00015074-12 |
NCGC00015074-14 |
NCGC00015074-15 |
NCGC00015074-17 |
NCGC00015074-22 |
NCGC00023455-03 |
NCGC00023455-04 |
NCGC00023455-05 |
NCGC00023455-06 |
NCGC00023455-07 |
NCGC00256374-01 |
NCGC00259108-01 |
NCGC00260724-01 |
AC-12779 |
AS-13169 |
H501 |
SBI-0050028.P004 |
2-Acetamido-5-sulfonamido-1,4-thiadiazole |
5-Acetamide-1,4-thiadiazole-2-sulfonamide |
DB-053437 |
5-Acetamido-1,3,4-thiadiazol-2-sulfonamide |
AB00051906 |
EU-0100039 |
ST45022057 |
1,4-Thiadiazole-2-sulfonamide, 5-acetamido- |
C06805 |
D00218 |
D88526 |
J10059 |
20506-EP2269989A1 |
20506-EP2275420A1 |
20506-EP2280008A2 |
20506-EP2295406A1 |
20506-EP2298772A1 |
20506-EP2308562A2 |
20506-EP2308839A1 |
20506-EP2314585A1 |
AB00051906_15 |
003A105 |
A832415 |
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)ethanamide |
Q413690 |
L 579486 |
Q-200579 |
Q-200580 |
SR-01000000065-2 |
SR-01000000065-4 |
SR-01000000065-6 |
BRD-K43457670-001-22-9 |
BRD-K43457670-001-26-0 |
Z277559108 |
Acetazolamide, European Pharmacopoeia (EP) Reference Standard |
Acetazolamide, United States Pharmacopeia (USP) Reference Standard |
N - (5 - Sulfamoyl - 1,3, 4 - thiadiazol - 2 - yl) acetamide |
Acetazolamide for system suitability, European Pharmacopoeia (EP) Reference Standard |
Acetazolamide, Pharmaceutical Secondary Standard; Certified Reference Material |
124442-28-0 |
2-Acetamido-5-sulfamoyl-1,3,4-thiadiazole; 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide |
Experimental Data
acetazolamide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -13 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
acetazolamide
Statistics Data
acetazolamide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -13 | 1 | 1 |
Statistics Data Visualization
acetazolamide
