Compound Summary
Compound Information
Palmatine
Compound Name: | Palmatine |
Compound CID: | 19009 |
Synonyms: | Palmatine 3486-67-7 Berbericinine O,O-Dimethyldemethyleneberberine Burasaine More... |
Iupac Name: | 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium |
InChI: | InChI=1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1 |
InChIKey: | QUCQEUCGKKTEBI-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC |
Isomeric Smiles: | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC |
Molecular Weight: | 352.4 |
Molecular Formula: | C21H22NO4+ |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Palmatine
Molecular Weight: | 352.4 |
Molecular Formula: | C21H22NO4+ |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 26 |
Complexity: | 475 |
Synonyms
Palmatine
| Palmatine | Palmatine |
|---|---|
Palmatine |
3486-67-7 |
Berbericinine |
O,O-Dimethyldemethyleneberberine |
Burasaine |
Dibenzoa,gquinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy- |
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino2,1-bisoquinolin-7-ium |
Calystigine |
UNII-G50C034217 |
7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium |
5,6-Dihydro-2,3,9,10-tetramethoxydibenzoa,gquinolizinium |
C21H22NO4 |
CHEBI:16096 |
GNF-PF-4086 |
2,3,9,10-tetramethoxy-5,6-dihydroisoquino3,2-aisoquinolinium |
5,6-Dihydro-2,3,9,10-tetramethoxydibenzo(a,g)quinolizinium |
Palmatin |
Dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy- |
G50C034217 |
5,6-Dihydro-2,3,9,10-tetramethoxy-dibenzoa,gquinolizinium |
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino3,2-aisoquinolin-7-ium |
CHEMBL274189 |
BRN 1555498 |
Hindarinine |
SR-01000841226 |
Palmatine-chloride |
PALMITINE |
Spectrum_001849 |
SpecPlus_000619 |
SpecPlus_000738 |
Prestwick0_000579 |
Prestwick1_000579 |
Prestwick2_000579 |
Prestwick3_000579 |
Spectrum2_000608 |
Spectrum3_000907 |
Spectrum4_001005 |
Spectrum5_000684 |
Spectrum5_001860 |
Palmatine pound>>Fibrauretin |
BSPBio_000398 |
BSPBio_002629 |
KBioGR_001469 |
KBioSS_002363 |
5-21-06-00202 (Beilstein Handbook Reference) |
DivK1c_006715 |
DivK1c_006834 |
SCHEMBL562120 |
SPBio_000516 |
SPBio_002617 |
BPBio1_000438 |
CHEMBL206106 |
DTXSID9048065 |
HY-N0110A |
KBio1_001659 |
KBio1_001778 |
KBio2_002360 |
KBio2_004928 |
KBio2_007496 |
KBio3_001854 |
7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxyberbinium |
HMS3885G04 |
ZINC608233 |
2,3,9,10-tetramethoxy-5,6-dihydro-isoquino3,2-aisoquinolinylium |
BBL028417 |
BDBM50292332 |
BERBINIUM, 7,8,13,13a-TETRAHYDRO-2,3,9,10-TETRAMETHOXY- |
MFCD00221758 |
s3769 |
STK801361 |
AKOS005612997 |
AC-7992 |
CCG-268056 |
MCULE-8294668918 |
SDCCGMLS-0066652.P001 |
NCGC00016631-01 |
NCGC00016631-02 |
NCGC00016631-03 |
NCI60_001757 |
CAS-3486-67-7 |
AB0020612 |
DB-048694 |
CS-0013950 |
FT-0603638 |
C05315 |
A822452 |
Q-100422 |
Q6634283 |
SR-01000841226-5 |
BRD-K58466253-003-04-1 |
BRD-K58466253-003-07-4 |
2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino3,2-aisoquinolinylium; chloride |
Experimental Data
Palmatine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10 | umol/L | 15.13 | 14.95 | -1.15 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 17.08 | 15.47 | -9.401 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 44.8 | 43.32 | -3.301 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 45.44 | 44.54 | -1.983 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
Palmatine
Statistics Data
Palmatine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.15 | 1 | 2 | |
| Drosophila melanogaster | -1.983 | 1 | 2 |
Statistics Data Visualization
Palmatine
