Compound Summary
Compound Information
UNII-UT87RB8I1V
Compound Name: | UNII-UT87RB8I1V |
Compound CID: | 189711 |
Synonyms: | UNII-UT87RB8I1V 111466-41-2 MK-912 UT87RB8I1V MK 912 More... |
Iupac Name: | (2S,12bS)-1',3'-dimethylspiro[1,3,4,6,7,12b-hexahydro-[1]benzofuro[2,3-a]quinolizine-2,4'-1,3-diazinane]-2'-one |
InChI: | InChI=1S/C20H25N3O2/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20/h3-6,16H,7-13H2,1-2H3/t16-,20+/m0/s1 |
InChIKey: | JRDUBBHIPPPSLP-OXJNMPFZSA-N |
Canonical Smiles: | CN1CCC2(CCN3CCC4=C(C3C2)OC5=CC=CC=C45)N(C1=O)C |
Isomeric Smiles: | CN1CC[C@]2(CCN3CCC4=C([C@@H]3C2)OC5=CC=CC=C45)N(C1=O)C |
Molecular Weight: | 339.4 |
Molecular Formula: | C20H25N3O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
UNII-UT87RB8I1V
Molecular Weight: | 339.4 |
Molecular Formula: | C20H25N3O2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 25 |
Complexity: | 555 |
Synonyms
UNII-UT87RB8I1V
| UNII-UT87RB8I1V | UNII-UT87RB8I1V |
|---|---|
UNII-UT87RB8I1V |
111466-41-2 |
MK-912 |
UT87RB8I1V |
MK 912 |
L 657743 |
L-657,743 |
(2S,12bS)-1,3-dimethylspiro1,3,4,6,7,12b-hexahydro-1benzofuro2,3-aquinolizine-2,4-1,3-diazinane-2-one |
L-657,743-002W |
L 657,743 |
1,3-Dimethylspiro(1,3,4,5,6,6,7,12b-octahydro-2H-benzo(b)furo(2,3-a)quinolizine)-2,4-pyrimidin-2-one |
CHEMBL1257057 |
SCHEMBL15902756 |
DTXSID60912170 |
ZINC4475284 |
Q27291261 |
(2S,12BS)-1,3-dimethyl-1,3,4,5,6,6,7,12b-octahydro-1H-spirobenzofuro2,3-aquinolizine-2,4-pyrimidin-2(3H)-one" |
1,3-Dimethyl-1,3,4,6,7,12b-hexahydrospiro1-benzofuro2,3-aquinolizine-2,4-1,3diazinan-2-one" |
Spiro(2H-benzofuro(2,3-a)quinolizine-2,4(1H)-pyrimidin)-2(3H)-one, 1,3,4,5,6,6,7,12b-octahydro-1,3-dimethyl-, (2S-trans)-" |
Experimental Data
UNII-UT87RB8I1V
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 8 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
UNII-UT87RB8I1V
Statistics Data
UNII-UT87RB8I1V
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8 | 1 | 1 |
Statistics Data Visualization
UNII-UT87RB8I1V
