Compound Summary
Compound Information
7-Chlorokynurenic acid
Compound Name: | 7-Chlorokynurenic acid |
Compound CID: | 1884 |
Synonyms: | 7-Chlorokynurenic acid 18000-24-3 7-Chloro-4-hydroxyquinoline-2-carboxylic acid 7-CKA 7-Cl-KYNA More... |
Iupac Name: | 7-chloro-4-oxo-1H-quinoline-2-carboxylic acid |
InChI: | InChI=1S/C10H6ClNO3/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13/h1-4H,(H,12,13)(H,14,15) |
InChIKey: | UAWVRVFHMOSAPU-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)O |
Isomeric Smiles: | C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)O |
Molecular Weight: | 223.61 |
Molecular Formula: | C10H6ClNO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
7-Chlorokynurenic acid
Molecular Weight: | 223.61 |
Molecular Formula: | C10H6ClNO3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 15 |
Complexity: | 340 |
Synonyms
7-Chlorokynurenic acid
| 7-Chlorokynurenic acid | 7-Chlorokynurenic acid |
|---|---|
7-Chlorokynurenic acid |
18000-24-3 |
7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
7-CKA |
7-Cl-KYNA |
UNII-S7936QON2K |
7-chloro-4-hydroxy-2-carboxyquinoline |
7CKA |
7-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid |
CHEMBL311389 |
S7936QON2K |
CHEBI:63965 |
7-chloro-4-oxo-1H-quinoline-2-carboxylic acid |
2-Quinolinecarboxylic acid, 7-chloro-4-hydroxy- |
77474-31-8 |
7-Chloro-kynurenic acid |
SR-01000076227 |
EINECS 241-913-6 |
NSC 149792 |
7-chloro-4-oxo-1H-quinoline-2-carboxylic acid. |
Ageloline A |
CKA |
7-chlorokynurenic-acid |
Spectrum_001451 |
Tocris-0237 |
SpecPlus_000720 |
Lopac-C-121 |
Spectrum2_001470 |
Spectrum3_001942 |
Spectrum4_000084 |
Spectrum5_001162 |
Biomol-NT_000199 |
Lopac0_000362 |
BSPBio_003542 |
KBioGR_000348 |
KBioSS_001931 |
DivK1c_006816 |
SCHEMBL157187 |
SPECTRUM1502059 |
SPBio_001399 |
BPBio1_001230 |
7-Chlorokynurenic acid, 98+% |
DTXSID7042568 |
KBio1_001760 |
KBio2_001931 |
KBio2_004499 |
KBio2_007067 |
KBio3_002826 |
2-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo- |
HMS3266C21 |
HMS3411C11 |
HMS3675C11 |
ZINC8660417 |
BDBM50005001 |
CCG-39180 |
MFCD00069227 |
NSC149792 |
AKOS023250576 |
NSC-149792 |
SB21215 |
NCGC00015183-01 |
NCGC00015183-02 |
NCGC00015183-03 |
NCGC00015183-04 |
NCGC00015183-05 |
NCGC00015183-06 |
NCGC00015183-07 |
NCGC00024511-01 |
NCGC00024511-02 |
NCGC00024511-03 |
NCGC00024511-04 |
NCGC00024511-05 |
NCGC00024511-06 |
AS-52646 |
DB-065303 |
HY-100811 |
B6232 |
C-121 |
C-285 |
CS-0020453 |
EU-0100362 |
FT-0705682 |
2-Quinolinecarboxylicacid,7-chloro-4-hydroxy- |
7-Chloro-4-hydroxy-quinoline-2-carboxylic acid |
A17070 |
P15444 |
J-011490 |
SR-01000076227-1 |
SR-01000076227-3 |
BRD-K84214706-001-03-2 |
BRD-K84214706-001-04-0 |
Q15634175 |
7-Chloro-1,4-dihydro-4-oxoquinoline-2-carboxylic acid |
7-Chloro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid |
7-Chloro-4-hydroxy-quinoline-2-carboxylic acid (7-chloro-kynurenate) |
Experimental Data
7-Chlorokynurenic acid
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
7-Chlorokynurenic acid
Statistics Data
7-Chlorokynurenic acid
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3 | 1 | 1 |
Statistics Data Visualization
7-Chlorokynurenic acid
