Compound Summary
Compound Information
stavudine
Compound Name: | stavudine |
Compound CID: | 18283 |
Synonyms: | stavudine 3056-17-5 sanilvudine Zerit 2,3-Didehydro-3-deoxythymidine More... |
Iupac Name: | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione |
InChI: | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 |
InChIKey: | XNKLLVCARDGLGL-JGVFFNPUSA-N |
Canonical Smiles: | CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO |
Isomeric Smiles: | CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO |
Molecular Weight: | 224.21 |
Molecular Formula: | C10H12N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
stavudine
Molecular Weight: | 224.21 |
Molecular Formula: | C10H12N2O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 16 |
Complexity: | 388 |
Synonyms
stavudine
| stavudine | stavudine |
|---|---|
stavudine |
3056-17-5 |
sanilvudine |
Zerit |
2,3-Didehydro-3-deoxythymidine |
Zerit Xr |
BMY-27857 |
Estavudina |
Stavudinum |
Stavudinum INN-Latin |
Estavudina INN-Spanish |
d4T |
Thymidine, 2,3-didehydro-3-deoxy-" |
3-Deoxy-2-thymidinene |
ddeThd |
2,3-Didehydro-3-deoxythimidine |
BMY 27857 |
3-Deoxy-2,3-didehydrothymidine |
Dideoxydidehydrothymidine |
1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione |
UNII-BO9LE4QFZF |
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine |
NSC 163661 |
BO9LE4QFZF |
1-(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl-5-methylpyrimidine-2,4(1H,3H)-dione |
STV |
CHEMBL991 |
Zerut XR |
MLS000028546 |
CHEBI:63581 |
1-(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl-5-methylpyrimidine-2,4-dione |
1-(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE |
NCGC00023212-07 |
SMR000058350 |
D 4T (nucleoside) |
DSSTox_CID_3819 |
DSSTox_RID_77198 |
DSSTox_GSID_23819 |
Stavudine USAN:BAN:INN |
D 4T |
ddeTyd |
1-(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl-5-methyl-pyrimidine-2,4-dione |
CAS-3056-17-5 |
Zerit(TM) |
Sanilvudine (JAN) |
Zerit (TN) |
HSDB 7338 |
SR-01000075802 |
Stavudine (USAN/INN) |
BRN 0618327 |
D4T & GM-CSF |
2-Thymidinene, 3-deoxy- |
MFCD00132921 |
NSC163661 |
NSC-163661 |
Stavudine USAN:USP:INN:BAN |
Stavudine- Bio-X |
D4TMBY-27857-3 |
Opera_ID_1281 |
3-deoxythymidin-2-ene |
D 1413 |
cid_5155 |
1-((2R,5S)-5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione |
3-deoxy-2-thymidine |
Lopac0_000336 |
SCHEMBL38661 |
cid_18283 |
MLS000759504 |
MLS001055348 |
MLS001077292 |
MLS001424091 |
MLS006011922 |
BIDD:GT0082 |
D-4T |
2,3-Anhydrothymidine; d4T |
DTXSID1023819 |
1-(2,3-Dideoxy-beta-D-glycero-2-pentenofuranosyl)thymine |
HMS2051O20 |
HMS2234C10 |
HMS3039O05 |
HMS3259L21 |
HMS3261C13 |
HMS3428C07 |
HMS3714N22 |
Pharmakon1600-01502339 |
ZINC137884 |
BCP02952 |
HY-B0116 |
Tox21_110886 |
Tox21_201393 |
Tox21_300583 |
Tox21_500336 |
BBL033763 |
BDBM50013111 |
NSC759897 |
STK801888 |
2,3-Didehydro-3-deoxy-thymidine |
AKOS005622554 |
Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)- (7CI,8CI) |
Tox21_110886_1 |
AC-5263 |
CCG-100902 |
CS-1872 |
DB00649 |
KS-1115 |
LP00336 |
MCULE-9252477726 |
NC00152 |
NC00684 |
NSC-759897 |
SDCCGSBI-0050324.P002 |
2,3-didehydro-3-deoxythymidine" |
3-deoxy-2,3-didehydrothymidine" |
3-Deoxy-2,3-didehydro-D-thymidine |
NCGC00023212-03 |
NCGC00023212-04 |
NCGC00023212-05 |
NCGC00023212-08 |
NCGC00023212-09 |
NCGC00023212-10 |
NCGC00023212-11 |
NCGC00023212-12 |
NCGC00023212-13 |
NCGC00023212-14 |
NCGC00023212-25 |
NCGC00023212-30 |
NCGC00254372-01 |
NCGC00258944-01 |
NCGC00261021-01 |
Stavudine 100 microg/mL in Acetonitrile |
1-5-(hydroxymethyl)-2,5-dihydro-2-furanyl-5-methyl-2,4(1H,3H)-pyrimidinedione & Colony-stimulating factor 2 |
BD164571 |
H940 |
SMR000673569 |
2,3-didehydro-2,3-dideoxythymidine |
AB0013374 |
Thymidine, 2,3-didehydro-, 3-deoxy- |
D3580 |
EU-0100336 |
2,3-dideoxy-2,3-didehydrothymidine |
C07312 |
D00445 |
J10003 |
AB00383018_18 |
056S175 |
Q423984 |
J-700246 |
Q-201742 |
SR-01000075802-1 |
SR-01000075802-4 |
2,3-Didehydro-3-deoxythymidine, >=98% (TLC) |
Z1695906749 |
Stavudine, European Pharmacopoeia (EP) Reference Standard |
1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine |
Stavudine, United States Pharmacopeia (USP) Reference Standard |
1-(5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione |
1-(5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (ddeThd) |
1-(cis-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione |
1-(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl-5-methyl-2,4(1H,3H)-pyrimidinedione |
3- Azido-3-deoxythymidine & Granulocyte-macrophage colony-stimulating factor |
Stavudine for system suitability, European Pharmacopoeia (EP) Reference Standard |
1-(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl-5-methylpyrimidine-2,4-(1H,3H)-dione |
220020-60-0 |
Experimental Data
stavudine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
stavudine
Statistics Data
stavudine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
stavudine
