Compound Summary
Compound Information
5-(N,N-Hexamethylene)amiloride
Compound Name: | 5-(N,N-Hexamethylene)amiloride |
Compound CID: | 1794 |
Synonyms: | 5-(N,N-Hexamethylene)amiloride 5-(N,N-hexamethylene)-Amiloride 1428-95-1 Hexamethyleneamiloride Hexamethylene amiloride More... |
Iupac Name: | 3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide |
InChI: | InChI=1S/C12H18ClN7O/c13-8-10(20-5-3-1-2-4-6-20)18-9(14)7(17-8)11(21)19-12(15)16/h1-6H2,(H2,14,18)(H4,15,16,19,21) |
InChIKey: | RQQJJXVETXFINY-UHFFFAOYSA-N |
Canonical Smiles: | C1CCCN(CC1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
Isomeric Smiles: | C1CCCN(CC1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
Molecular Weight: | 311.77 |
Molecular Formula: | C12H18ClN7O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
5-(N,N-Hexamethylene)amiloride
Molecular Weight: | 311.77 |
Molecular Formula: | C12H18ClN7O |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 21 |
Complexity: | 393 |
Synonyms
5-(N,N-Hexamethylene)amiloride
| 5-(N,N-Hexamethylene)amiloride | 5-(N,N-Hexamethylene)amiloride |
|---|---|
5-(N,N-Hexamethylene)amiloride |
5-(N,N-hexamethylene)-Amiloride |
1428-95-1 |
Hexamethyleneamiloride |
Hexamethylene amiloride |
HMA-5 |
HMA |
N,N-HEXAMETHYLENEAMILORIDE |
Hexamethylene amiloride;HMA |
3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide |
3-Amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide |
CHEBI:76400 |
3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide |
5-HMA |
Spectrum_001596 |
SpecPlus_000779 |
Spectrum2_001669 |
Spectrum3_001662 |
Spectrum4_000623 |
Spectrum5_001388 |
Lopac-A-9561 |
3-Amino-N-(aminoiminomethyl)-6-chloro-5-(hexahydro-1H-azepin-1-yl)pyrazinecarboxamide |
Lopac0_000104 |
BSPBio_003443 |
KBioGR_001206 |
KBioSS_002076 |
MLS002153208 |
BIDD:GT0357 |
DivK1c_006875 |
SPECTRUM1504215 |
SPBio_001857 |
CHEMBL501701 |
GTPL1192 |
SCHEMBL7862943 |
SCHEMBL9852488 |
BDBM81818 |
KBio1_001819 |
KBio2_002076 |
KBio2_004644 |
KBio2_007212 |
KBio3_002663 |
DTXSID10162188 |
HMS2233N17 |
HMS3260E10 |
CAS_1794 |
NSC_1794 |
ZINC3871091 |
Tox21_500104 |
CCG-39661 |
MFCD00069211 |
PDSP1_001080 |
PDSP2_001064 |
CCG-221408 |
LP00104 |
SDCCGSBI-0050092.P003 |
Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(hexahydro-1H-azepin-1-yl)- |
NCGC00015108-01 |
NCGC00015108-02 |
NCGC00015108-03 |
NCGC00015108-04 |
NCGC00015108-05 |
NCGC00015108-06 |
NCGC00015108-09 |
NCGC00093601-01 |
NCGC00093601-02 |
NCGC00095333-01 |
NCGC00095333-02 |
NCGC00260789-01 |
SMR001230687 |
HY-128067 |
CS-0095166 |
EU-0100104 |
FT-0739004 |
H-130 |
A 9561 |
SR-01000075696 |
J-007715 |
SR-01000075696-1 |
BRD-K40990712-001-02-4 |
Q27073995 |
3-amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide |
3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide. |
1345839-29-3 |
Experimental Data
5-(N,N-Hexamethylene)amiloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
5-(N,N-Hexamethylene)amiloride
Statistics Data
5-(N,N-Hexamethylene)amiloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
5-(N,N-Hexamethylene)amiloride
