Compound Summary
Compound Information
phenytoin
Compound Name: | phenytoin |
Compound CID: | 1775 |
Synonyms: | phenytoin 5,5-DIPHENYLHYDANTOIN 57-41-0 Diphenylhydantoin Dilantin More... |
Iupac Name: | 5,5-diphenylimidazolidine-2,4-dione |
InChI: | InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19) |
InChIKey: | CXOFVDLJLONNDW-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3 |
Isomeric Smiles: | C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3 |
Molecular Weight: | 252.27 |
Molecular Formula: | C15H12N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
phenytoin
Molecular Weight: | 252.27 |
Molecular Formula: | C15H12N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 19 |
Complexity: | 350 |
Synonyms
phenytoin
| phenytoin | phenytoin |
|---|---|
phenytoin |
5,5-DIPHENYLHYDANTOIN |
57-41-0 |
Diphenylhydantoin |
Dilantin |
5,5-diphenylimidazolidine-2,4-dione |
Phenytoine |
Dihydantoin |
Aleviatin |
Dilabid |
Diphantoin |
Diphenylan |
Zentropil |
Epamin |
Diphedan |
Fenylepsin |
Lepitoin |
Phentytoin |
Sodanton |
Difenin |
Dihycon |
Lehydan |
Diphenylhydatanoin |
Dantoinal |
Di-Hydan |
Dilantine |
Dillantin |
Diphenine |
Diphentyn |
Ditoinate |
Elepsindon |
Epilantin |
Fenitoina |
Fenytoine |
Hidantilo |
Hidantina |
Hidantomin |
Hydantoinal |
Kessodanten |
Phanantin |
Phanatine |
Phenatoine |
Sodantoin |
Sylantoic |
Thilophenyl |
Zentronal |
Auranile |
Dantinal |
Dantoine |
Difetoin |
Difhydan |
Dintoin |
Dintoina |
Diphedal |
Diphenin |
Enkelfel |
Epifenyl |
Epihydan |
Fentoin |
Hidantal |
Hydantal |
Idantoil |
Idantoin |
Labopal |
Phentoin |
Ritmenal |
Saceril |
Sanepil |
Silantin |
Solantin |
Danten |
Denyl |
Epelin |
Epinat |
Epised |
Eptal |
Hidan |
Lepsin |
Ekko |
Ictalis simple |
Toin unicelles |
Dilantin acid |
Dantoinal klinos |
Om-Hydantoine |
Di-Phetine |
Epdantoine simple |
Hidantina vitoria |
Gerot-epilan-D |
Epilan-D |
Neosidantoina |
Comitoina |
Hidantina senosian |
Hydantol |
Minetoin |
Novantoina |
Causoin |
Convul |
Di-Lan |
Ekko capsules |
Neos-Hidantoina |
2,4-Imidazolidinedione, 5,5-diphenyl- |
Om hidantoina simple |
TOIN |
Phenhydanin |
Phenytex |
Sinergina |
Sodanthon |
Iphenylhydantoin |
Phenytoin-Gerot |
Difenilhidantoina |
Fenytoin Dak |
Didan TDC 250 |
Dilantin-125 |
Epdantoin Simple |
Phenytoin AWD |
Epilan D |
5,5-Diphenyl-2,4-imidazolidinedione |
Phenytoinum |
Diphenat |
Hindatal |
Hydantin |
Epanutin |
Fenitoina INN-Spanish |
Phenytoine INN-French |
Phenytoinum INN-Latin |
Difenilhidantoina Spanish |
Diphenylhydantoine French |
5,5-Dwufenylohydantoina |
Antisacer |
Fenantoin Mn Pharma |
Diphenylhydantoine |
Di-Lan (VAN) |
PHENYTOIN SODIUM |
Diphenylhydantoin (VAN) |
Diphentoin |
DILANTIN-30 |
Solantoin |
Solantyl |
Eptoin |
DPH (VAN) |
PHENYTEK |
5,5-Diphenylimidazolidin-2,4-dione |
5,5-Diphenyl-imidazolidine-2,4-dione |
5,5-Diphenylhydantoin (IUPAC) |
5,5-Dwufenylohydantoina Polish |
Hydantoin, 5,5-diphenyl- |
CCRIS 515 |
CHEBI:8107 |
NCI-C55765 |
5,5-Diphenylhydantoin (phenytoin) |
UNII-6158TKW0C5 |
Diphenylan sodium |
AI3-52498 |
Dilantin (TN) |
Novophenytoin |
MFCD00005264 |
MLS000069789 |
Citrulliamon |
Phenitoin |
5,5-diphenyltetrahydro-1H-2,4-imidazoledione |
Fenidantoin s |
NSC8722 |
6158TKW0C5 |
NSC-8722 |
Epasmir 5 |
NCGC00021139-03 |
SMR000059026 |
DSSTox_CID_541 |
Fenidantoin "s" |
DSSTox_RID_75650 |
DSSTox_GSID_20541 |
Epasmir "5" |
Didan-tdc-250 |
CAS-57-41-0 |
phenytoin (PHN) |
5,5-diphenyl-1,3-diazolidine-2,4-dione |
component of Mebroin |
fenidantoin s" |
epasmir 5 |
NSC 8722 |
630-93-3 |
EINECS 200-328-6 |
SR-01000075211 |
IFLab1_000214 |
Fenidantoin s |
HSDB 3160 |
Episar (Salt/Mix) |
Epasmir 5 |
Aladdin (Salt/Mix) |
Alepsin (Salt/Mix) |
Epsolin (Salt/Mix) |
Phenytoin (Lepitoin) |
Tacosal (Salt/Mix) |
Phenytoin USAN:USP:INN:BAN:JAN |
Antisacer (Salt/Mix) |
Epdantoin (Salt/Mix) |
Epileptin (Salt/Mix) |
Hydantoin,5-diphenyl- |
Spectrum_001105 |
Fenigramon (Salt/Mix) |
5,5-diphenyl hydantoin |
Citrullamon (Salt/Mix) |
Opera_ID_394 |
2, 5,5-diphenyl- |
CHEMBL16 |
Spectrum2_001281 |
Spectrum3_000890 |
Spectrum4_000984 |
Spectrum5_001369 |
Lopac-D-4007 |
ACMC-1AMO9 |
Epitope ID:117723 |
D 4007 |
SCHEMBL3440 |
BIDD:PXR0090 |
Lopac0_000329 |
Lopac0_000378 |
Oprea1_373280 |
BSPBio_001437 |
KBioGR_001387 |
KBioSS_001585 |
MLS001074087 |
MLS002454401 |
BIDD:GT0625 |
DivK1c_000507 |
Soluble phenytoin (Salt/Mix) |
SPBio_001281 |
Phenytoin (JP17/USP/INN) |
GTPL2624 |
2-hydroxy-5,5-diphenyl-3,5-dihydro-4H-imidazol-4-one |
DTXSID8020541 |
KBio1_000507 |
KBio2_001585 |
KBio2_004153 |
KBio2_006721 |
KBio3_001780 |
WLN: T5MVMV EHJ ER& ER |
5,5-Diphenylhydantoin, >=99% |
NINDS_000507 |
Phenytoin 1.0 mg/ml in Methanol |
SM-88 COMPONENT PHENYTOIN |
HMS1412J16 |
HMS1694O05 |
HMS1791H19 |
HMS1989H19 |
HMS2089E11 |
HMS2236J06 |
HMS3261K17 |
HMS3402H19 |
HMS3657O03 |
BCP05960 |
HY-B0448 |
Hydantoin, 5,5-diphenyl- (8CI) |
ZINC2510358 |
Tox21_110861 |
Tox21_202299 |
Tox21_300281 |
Tox21_500378 |
AC-376 |
BBL027509 |
BDBM50003655 |
BDBM50101816 |
s2525 |
SBB057224 |
STK058029 |
STK182871 |
STL454130 |
AKOS000416887 |
AKOS003245432 |
Tox21_110861_1 |
5,5-diphenylimidazolidine-2,4-dione. |
CCG-104011 |
CCG-221682 |
DB00252 |
LP00378 |
MCULE-2376673346 |
5,5-di(phenyl)imidazolidine-2,4-dione |
IDI1_000507 |
IDI1_008433 |
NCGC00015342-01 |
NCGC00015342-02 |
NCGC00015342-03 |
NCGC00015342-04 |
NCGC00015342-05 |
NCGC00015342-06 |
NCGC00015342-07 |
NCGC00015342-08 |
NCGC00015342-09 |
NCGC00015342-10 |
NCGC00015342-11 |
NCGC00015342-12 |
NCGC00021139-01 |
NCGC00021139-02 |
NCGC00021139-04 |
NCGC00021139-05 |
NCGC00021139-06 |
NCGC00021139-07 |
NCGC00021139-08 |
NCGC00021139-09 |
NCGC00021139-10 |
NCGC00021139-11 |
NCGC00091492-01 |
NCGC00091492-02 |
NCGC00091492-03 |
NCGC00091492-04 |
NCGC00091492-05 |
NCGC00093810-01 |
NCGC00093810-02 |
NCGC00254135-01 |
NCGC00259848-01 |
NCGC00261063-01 |
5,5-?Diphenyl-?2,4-?imidazolidinedione |
5,5-Diphenyl-1H-imidazolidine-2,4-dione |
D0894 |
EU-0100378 |
FT-0667653 |
FT-0699999 |
P-235 |
ST45024762 |
SW203757-2 |
EN300-16818 |
5,5-diphenylimidazolidine-2,4-dione;Phenytoin |
C07443 |
D00512 |
E76094 |
2,4-Imidazolidinedione, 5,5-diphenyl- (9CI) |
5,5-diphenyl-1H-imidazole-2,4(3H,5H)-dione |
AB00374253-10 |
AB00374253-11 |
AB00374253_13 |
A831435 |
Q410400 |
SR-01000003141 |
SR-01000003141-8 |
SR-01000075211-2 |
W-105468 |
BRD-K55930204-001-02-7 |
BRD-K55930204-236-11-0 |
Z56786458 |
4-hydroxy-5,5-diphenyl-1,5-dihydro-2H-imidazol-2-one |
F0020-1370 |
Phenytoin, European Pharmacopoeia (EP) Reference Standard |
Phenytoin, United States Pharmacopeia (USP) Reference Standard |
5,5-Diphenylhydantoin solution, drug standard, 1.0 mg/mL in methanol |
Phenytoin, Pharmaceutical Secondary Standard; Certified Reference Material |
Phenytoin for system suitability, European Pharmacopoeia (EP) Reference Standard |
Phenytoin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
Experimental Data
phenytoin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -1 | NS | N2 | 24134630 | Inactive | ||||||
| Mus musculus | 2 | mg | 450 | 558 | 24 | Unclear | 7390164 |
Experimental Data Visualization
phenytoin
Statistics Data
phenytoin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1 | 1 | 1 | |
| Mus musculus | 24 | 1 | 1 |
Statistics Data Visualization
phenytoin
