Compound Summary
Compound Information
NBI 27914
Compound Name: | NBI 27914 |
Compound CID: | 176157 |
Synonyms: | NBI 27914 NBI27914 184241-44-9 NBI-27914 CHEMBL45281 More... |
Iupac Name: | 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine |
InChI: | InChI=1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25) |
InChIKey: | KNADXBVKFAUMCR-UHFFFAOYSA-N |
Canonical Smiles: | CCCN(CC1CC1)C2=NC(=NC(=C2Cl)NC3=C(C=C(C=C3Cl)Cl)Cl)C |
Isomeric Smiles: | CCCN(CC1CC1)C2=NC(=NC(=C2Cl)NC3=C(C=C(C=C3Cl)Cl)Cl)C |
Molecular Weight: | 434.2 |
Molecular Formula: | C18H20Cl4N4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
NBI 27914
Molecular Weight: | 434.2 |
Molecular Formula: | C18H20Cl4N4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 26 |
Complexity: | 441 |
Synonyms
NBI 27914
| NBI 27914 | NBI 27914 |
|---|---|
NBI 27914 |
NBI27914 |
184241-44-9 |
NBI-27914 |
CHEMBL45281 |
5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine |
SR-01000075865 |
Tocris-1591 |
Lopac-N-3911 |
Lopac0_000493 |
MLS000860080 |
cid_176157 |
GTPL3512 |
SCHEMBL16606734 |
CHEBI:93069 |
DTXSID20171549 |
HMS2230I15 |
HMS3261D07 |
HMS3371C20 |
ZINC2511843 |
Tox21_500493 |
BDBM50054245 |
CCG-204584 |
LP00493 |
SDCCGSBI-0050477.P002 |
2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine |
NCGC00015737-01 |
NCGC00015737-02 |
NCGC00015737-03 |
NCGC00015737-04 |
NCGC00015737-05 |
NCGC00015737-08 |
NCGC00025224-01 |
NCGC00025224-02 |
NCGC00025224-03 |
NCGC00261178-01 |
SMR000326938 |
EU-0100493 |
NBI 27914, >=98% (HPLC) |
N 3911 |
SR-01000075865-1 |
BRD-K61177364-003-01-1 |
Q27087858 |
4,6-Pyrimidinediamine, 5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-n-(2,4,6-trichlorophenyl) |
5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)-aminopyridine |
5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine" |
5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N/-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE H" |
5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N-(2,4,6-trichloro-phenyl)-pyrimidine-4,6-diamine" |
5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N-(2,4,6-trichloro-phenyl)-pyrimidine-4,6-diamine |
5-CHLORO-N4-(CYCLOPROPYLMETHYL)-2-METHYL-N4-PROPYL-N6-(2,4,6-TRICHLOROPHENYL)PYRIMIDINE-4,6-DIAMINE |
Experimental Data
NBI 27914
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 23 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
NBI 27914
Statistics Data
NBI 27914
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 23 | 1 | 1 |
Statistics Data Visualization
NBI 27914
