Compound Summary
Compound Information
152121-47-6
Compound Name: | 152121-47-6 |
Compound CID: | 176155 |
Synonyms: | 152121-47-6 SB 203580 SB-203580 SB203580 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole More... |
Iupac Name: | 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine |
InChI: | InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25) |
InChIKey: | CDMGBJANTYXAIV-UHFFFAOYSA-N |
Canonical Smiles: | CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F |
Isomeric Smiles: | CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F |
Molecular Weight: | 377.4 |
Molecular Formula: | C21H16FN3OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
152121-47-6
Molecular Weight: | 377.4 |
Molecular Formula: | C21H16FN3OS |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 27 |
Complexity: | 500 |
Synonyms
152121-47-6
| 152121-47-6 | 152121-47-6 |
|---|---|
152121-47-6 |
SB 203580 |
SB-203580 |
SB203580 |
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole |
4-4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-ylpyridine |
4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine |
RWJ 64809 |
CHEBI:90705 |
4-(4-Fluorophenyl)-2-4-(methylsulfinyl)phenyl-5-(4-pyridyl)-1H-imidazole |
CHEMBL10 |
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
4-(4-(4-Fluorophenyl)-2-(4-(methylsulfinyl)-phenyl)-1H-imidazol-5-yl)pyridine |
C21H16FN3OS |
PB 203580 |
4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine |
MFCD00922198 |
4-5-(4-Fluorophenyl)-2-4-(methylsulfonyl)phenyl-1H-imidazol-4-ylpyridine |
4-4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-ylpyridine |
4-5-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-3H-imidazol-4-ylpyridine |
4-{4-(4-fluorophenyl)-2-4-(methylsulfinyl)phenyl-1H-imidazol-5-yl}pyridine |
SR-01000597367 |
1pme |
InSolution™ SB 203580 |
Kinome_2521 |
Tocris-1202 |
Tocris-1402 |
cc-50 |
Pyridine, 4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)- |
CBiol_001970 |
SCHEMBL95208 |
BSPBio_001104 |
MLS006010840 |
cid_176155 |
GTPL5269 |
DTXSID2040577 |
BDBM13336 |
AOB6367 |
EX-A134 |
SYN1074 |
4-5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL-PYRIDINE |
BCPP000074 |
BDBM192501 |
Bio1_000256 |
Bio1_000745 |
Bio1_001234 |
HMS1792H05 |
HMS1990H05 |
HMS3229O04 |
HMS3244I15 |
HMS3244I16 |
HMS3244J15 |
HMS3267B07 |
HMS3295M11 |
HMS3403H05 |
HMS3412M17 |
HMS3654M15 |
HMS3676M17 |
BCP01763 |
BDBM50045333 |
NSC755772 |
s1076 |
AKOS005145971 |
AKOS015994568 |
AM81234 |
CCG-206878 |
CS-0140 |
ES-0013 |
NSC-755772 |
SB16633 |
NCGC00025035-01 |
NCGC00025035-02 |
NCGC00025035-03 |
NCGC00025035-04 |
NCGC00025035-05 |
NCGC00381704-12 |
AC-32046 |
HY-10256 |
QC-11773 |
SMR004701767 |
AB0033710 |
DB-026130 |
FT-0674525 |
SW218141-2 |
X7403 |
EC-000.2318 |
F17411 |
K00038 |
SB 203580, solid, >=98% (HPLC) |
SB 203580 & Z-100 |
121S476 |
J-008891 |
J-513573 |
Q7389023 |
SR-01000597367-1 |
BRD-A37704979-001-02-4 |
BRD-A37704979-003-01-2 |
SB203580,RWJ 64809,PB 203580 |
SB 203580 - CAS 152121-47-6 |
US9187470, 104 (SB203580) |
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazol |
4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)imidazole |
4-(4-Fluorophenyl)-2-4-(methylsulfinyl)phenyl-5-(4-pyridyl)-1H-imidazole;SB-203580 |
4-{4-(4-fluorophenyl)-2-4-(methanesulfinyl)phenyl-1H-imidazol-5-yl}pyridine |
Pyridine, 4-4-(4-fluorophenyl)-2-4-(methylsulfinyl)phenyl-1H-imidazol-5-yl- |
Pyridine, 4-5-(4-fluorophenyl)-2-4-(methylsulfinyl)phenyl-1H-imidazol-yl- |
Pyridine, 4-5-(4-fluorophenyl)-2-4-(methylsulfinyl)phenyl-1H-imidazol-yl- & Z-100 |
RWJ-64809|||PB-203580|||4-4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-ylpyridine |
Experimental Data
152121-47-6
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 300 | umol/L | 30.3 | S | Oregon-R | 22363408 | Active |
Experimental Data Visualization
152121-47-6
Statistics Data
152121-47-6
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 30.3 | 1 | 1 |
Statistics Data Visualization
152121-47-6
