Compound Summary
Compound Information
biotin
Compound Name: | biotin |
Compound CID: | 171548 |
Synonyms: | biotin d-biotin 58-85-5 vitamin H Vitamin B7 More... |
Iupac Name: | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid |
InChI: | InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 |
InChIKey: | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
Canonical Smiles: | C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 |
Isomeric Smiles: | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2 |
Molecular Weight: | 244.31 |
Molecular Formula: | C10H16N2O3S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
biotin
Molecular Weight: | 244.31 |
Molecular Formula: | C10H16N2O3S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 16 |
Complexity: | 298 |
Synonyms
biotin
| biotin | biotin |
|---|---|
biotin |
d-biotin |
58-85-5 |
vitamin H |
Vitamin B7 |
coenzyme R |
Bioepiderm |
Bios II |
Factor S |
D(+)-Biotin |
Biodermatin |
Medebiotin |
(+)-Biotin |
D-(+)-Biotin |
Biotinum |
Biotine |
Meribin |
Factor S (vitamin) |
Lutavit H2 |
Biotina |
3H-Biotin |
NSC 63865 |
CCRIS 3932 |
HSDB 346 |
Injacom H |
5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno3,4-dimidazol-4-yl)pentanoic acid |
cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid |
cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid |
1swk |
1swn |
1swr |
MFCD00005541 |
Rovimix H 2 |
D-Biotin Factor S |
UNII-6SO6U10H04 |
5-(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno3,4-dimidazolidin-4-ylpentanoic acid |
AI3-51198 |
5-(3aS,4S,6aR)-2-oxohexahydro-1H-thieno3,4-dimidazol-4-ylpentanoic acid |
5-(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno3,4-dimidazol-4-ylpentanoic acid |
cis-(+)-Tetrahydro-2-oxothieno3,4imidazoline-4-valeric acid |
(+)-cis-Hexahydro-2-oxo-1H-thieno3,4imidazole-4-valeric acid |
1H-thieno3,4-dimidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)- |
1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4beta,6aalpha))- |
2-Keto-3,4-imidazolido-2-tetrahydrothiophene-N-valeric acid |
CHEBI:15956 |
6SO6U10H04 |
(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-valeric acid |
Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid, (3aS-(3aalpha,4beta,6aalpha))- |
22377-59-9 |
beta-Biotin |
5-(2-Oxohexahydro-1H-thieno3,4-dimidazol-4-yl)pentanoic acid |
DSSTox_CID_2679 |
Vitamin Bw |
(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno3,4-dimidazole-4-valeric acid |
(3aS-(3aalpha,4b,6aalpha))-Hexahydro-2-oxo-1H-thieno(3,4-d)imidaz- ole-4-pentanoic acid |
DSSTox_RID_76688 |
DSSTox_GSID_22679 |
medobiotin |
Deacura |
Gabunat |
Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid |
Rombellin |
Biokur |
Biotine INN-French |
Biotinum INN-Latin |
Biotina INN-Spanish |
Biotin Gelfert |
Biotin Hermes |
Biotine Roche |
Gelfert, Biotin |
Biotin ratiopharm |
Biotin-ratiopharm |
Hermes, Biotin |
Roche, Biotine |
1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)- |
5-((3AS,4S,6aR)-rel-2-oxohexahydro-1H-thieno3,4-dimidazol-4-yl)pentanoic acid |
BTN |
SMR000112255 |
D(+)Biotin |
EINECS 200-399-3 |
Biotin USP:INN:JAN |
hexahydro-2-oxo-1H-thieno3,4-dimidazole-4-pentanoic acid |
d-biotine |
delta-Biotin |
Vitamin-h |
NSC-63865 |
L-Biotin |
1avd |
1ndj |
1stp |
1swg |
1swp |
2avi |
4bcs |
4ggz |
4jnj |
Bioepiderm (TN) |
CAS-58-85-5 |
Bios H |
NCGC00094984-04 |
1H-Thieno3,4-dimidazole-4-pentanoic acid, hexahydro-2-oxo-, 3as-(3aalpha,4beta,6aalpha)- |
Biotin111In |
delta-(+)-Biotin |
Biotin (8CI) |
delta-biotin factor s |
1df8 |
1n9m |
2gh7 |
3t2w |
4bj8 |
Prestwick0_000418 |
Prestwick1_000418 |
Prestwick2_000418 |
Prestwick3_000418 |
cid_253 |
BDBM12 |
Biotin Silver Nanoparticles |
bmse000227 |
CHEMBL857 |
Probes2_000006 |
SCHEMBL8763 |
BSPBio_000376 |
22879-79-4 |
56846-45-8 |
Biotin (JP17/USP/INN) |
MLS001066402 |
MLS001074888 |
MLS001331736 |
MLS001333089 |
D-Biotin, analytical standard |
SPBio_002315 |
BPBio1_000414 |
cid_171548 |
GTPL4787 |
DTXSID7022679 |
AMF0005 |
1n43 |
2f01 |
Biotin, >=99.0% (T) |
HMS1569C18 |
HMS2096C18 |
HMS2271O06 |
HMS3713C18 |
HY-B0511 |
Tox21_113050 |
Tox21_302161 |
AC8089 |
BBL028095 |
Biotin, tested according to Ph.Eur. |
s3130 |
STK801941 |
ZINC35024346 |
AKOS001287669 |
Tox21_113050_1 |
CCG-220418 |
DB00121 |
EBD2202242 |
MCULE-7440963355 |
MD-1003 |
1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4b,6aalpha))- |
D-Biotin 10 microg/mL in Acetonitrile |
Biotin, meets USP testing specifications |
Biotin, SAJ special grade, >=98.0% |
NCGC00179580-01 |
NCGC00179580-02 |
NCGC00179580-04 |
NCGC00255377-01 |
AC-19998 |
BP-20441 |
ST055761 |
AB0068872 |
Biotin, >=99% (TLC), lyophilized powder |
Biotin, Vetec(TM) reagent grade, >=99% |
AB00374191 |
B0463 |
Biotin Impurity D - mixture of diastereomers |
58B855 |
C00120 |
D00029 |
M02926 |
AB00374191-08 |
AB00374191_11 |
A929752 |
Biotin, plant cell culture tested, >=99% (TLC) |
Q181354 |
SR-01000765521 |
Biotin, certified reference material, TraceCERT(R) |
Q-200929 |
SR-01000765521-2 |
BRD-K89210380-001-03-8 |
BRD-K89210380-001-13-7 |
6AE43AA3-BC3D-4C49-9DB9-5913A2401EB6 |
Biotin, European Pharmacopoeia (EP) Reference Standard |
F2173-0855 |
Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoate |
Z210803762 |
Biotin, United States Pharmacopeia (USP) Reference Standard |
cis-(+)-Tetrahydro-2-oxothieno3,4imidazoline-4-valerate |
(+)-cis-Hexahydro-2-oxo-1H-thieno3,4imidazole-4-valerate |
5-(2-oxohexahydro-1H-thieno3,4-dimidazol-4-yl)pentanoate |
Daunorubicin hydrochloride, Antibiotic for Culture Media Use Only |
(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno3,4-dimidazole-4-valerate |
Biotin, Pharmaceutical Secondary Standard; Certified Reference Material |
1H-Thieno3,4-dimidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)- (9CI) |
5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno3,4-dimidazol-6-yl)-pentanoic acid |
5-(3aR,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno3,4-dimidazol-6-ylpentanoic acid |
Biotin for system suitability, European Pharmacopoeia (EP) Reference Standard |
hexahydro-2-oxo-3aS-(3aa,4b,6aa)-1H-Thieno3,4-dimidazole-4-pentanoate |
hexahydro-2-oxo-3aS-(3aa,4b,6aa)-1H-Thieno3,4-dimidazole-4-pentanoic acid |
hexahydro-2-oxo-3as-(3alpha,4beta,6alpha)-1H-Thieno3,4-dimidazole-4-pentanoate |
hexahydro-2-oxo-3as-(3alpha,4beta,6alpha)-1H-Thieno3,4-dimidazole-4-pentanoic acid |
BIOTIN, PharmaGrade, USP, meets FCC testing specifications, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production. |
Biotin, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99% |
Experimental Data
biotin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 0.0067 | g/kg | 13.3 | 13.3 | 0 | NS | Oregon-R | 18856648 | Inactive |
Experimental Data Visualization
biotin
Statistics Data
biotin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 0 | 1 | 1 |
Statistics Data Visualization
biotin
