Compound Summary
Compound Information
HYDROXYPROGESTERONE CAPROATE
Compound Name: | HYDROXYPROGESTERONE CAPROATE |
Compound CID: | 169870 |
Synonyms: | HYDROXYPROGESTERONE CAPROATE 630-56-8 Delalutin Primolut Depot Hydroxyprogesterone hexanoate More... |
Iupac Name: | [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate |
InChI: | InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1 |
InChIKey: | DOMWKUIIPQCAJU-LJHIYBGHSA-N |
Canonical Smiles: | CCCCCC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(=O)C |
Isomeric Smiles: | CCCCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)C(=O)C |
Molecular Weight: | 428.6 |
Molecular Formula: | C27H40O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
HYDROXYPROGESTERONE CAPROATE
Molecular Weight: | 428.6 |
Molecular Formula: | C27H40O4 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 31 |
Complexity: | 797 |
Synonyms
HYDROXYPROGESTERONE CAPROATE
| HYDROXYPROGESTERONE CAPROATE | HYDROXYPROGESTERONE CAPROATE |
|---|---|
HYDROXYPROGESTERONE CAPROATE |
630-56-8 |
Delalutin |
Primolut Depot |
Hydroxyprogesterone hexanoate |
Hormofort |
Proge |
Proluton Depot |
Estralutin |
Hyproval |
Kaprogest |
Neolutin |
Syngynon |
Lutate |
Relutin |
Progesterone caproate |
Neolutin forte |
Depo-Proluton |
17-Caproxyprogesterone |
17alpha-Hydroxyprogesterone caproate |
Idrogestene |
Duraluton |
Hylutin |
Hyroxon |
Luteocrin |
Lutopron |
Teralutil |
Luteocrin depot |
Hyproval-PA |
Corlutin L.A. |
Gesterol LA 250 |
NSC-17592 |
17-alpha-hydroxy-progesterone caproate |
17a-hydroxyprogesterone caproate |
Progesterone retard pharlon |
17alpha-Caproyloxypregn-4-ene-3,20-dione |
17-alpha-Hydroxyprogesterone caproate |
MLS000028438 |
UNII-276F2O42F5 |
17alpha-Hydroxyprogesterone hexanoate |
17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione |
Progesterone, 17-hydroxy-, hexanoate |
SMR000058336 |
MLS001148643 |
CHEBI:5812 |
Makena |
Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate |
17.alpha.-Hydroxyprogesterone caproate |
276F2O42F5 |
(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopentaaphenanthren-17-yl hexanoate |
17.alpha.-Hydroxyprogesterone hexanoate |
NCGC00021268-03 |
17.alpha.-Hydroxyprogesterone n-caproate |
DSSTox_CID_23915 |
DSSTox_RID_80089 |
DSSTox_GSID_43915 |
3,20-Dioxopregn-4-en-17-yl hexanoate |
(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopentaaphenanthren-17-yl hexanoate |
Gestiva |
Hexanoic acid, ester with 17-hydroxypregn-4-ene-3,20-dione |
Delalutin (TN) |
(1S,11S,15S,2R,10R,14R)-14-acetyl-2,15-dimethyl-5-oxotetracyclo8.7.0.0<2,7>.0 <11,15>heptadec-6-en-14-yl hexanoate |
CAS-630-56-8 |
17|A-Hydroxyprogesterone caproate |
Idroprogesterone caproato |
Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)- |
Pregn-4-ene-3,20-dione, 17-(1-oxohexyl)oxy- |
Hydroxyprogesteroni caproas |
Lewntogest |
17-OHPC |
Caproate dhydroxyprogesterone |
Caproato de hidroxiprogesterona |
Idroprogesterone caproato DCIT |
17|A-Hydroxyprogesterone hexanoate |
Hyproval P.A. |
EINECS 211-138-8 |
Hylutin (TN) |
17 alpha-hydroxyprogesterone caproate |
Makena (TN) |
17-alpha-Hydroxyprogesterone hexanoate |
17alpha-Hydroxyprogesterone n-caproate |
Hydroxyprogesteroni caproas INN-Latin |
Progesterone, hexanoate |
Oxiprogesterone Caproate |
17-alpha-Hydroxy progesterone n-caproate |
17-Caproyloxyprogesterone |
3,20-Dioxo-4-pregnen-17alpha-yl hexanoat |
3,20-Dioxopregn-4-en-17alpha-yl caproate |
Caproate dhydroxyprogesterone INN-French |
Hydroxyprogesterone caproate USP:INN:JAN |
Opera_ID_1479 |
17alpha-Hydroxyprogesterone-17alpha caproate |
17-alpha-Hexanoyloxypregn-4-ene-3,20-dione |
17-Hydroxypregn-4-ene-3,20-dione hexanoate |
Caproato de hidroxiprogesterona INN-Spanish |
Deluteval 2X (Salt/Mix) |
SCHEMBL5330 |
MLS002207289 |
17alpha-Caproyloxyprogesterone |
ARONIS24417 |
17-hydroxyprogesterone-caproate |
Caproic acid hydroxyprogesterone |
cid_169870 |
CHEMBL1200848 |
DTXSID6043915 |
BDBM70293 |
17a-Hydroxyprogesterone hexanoate |
17alpha-Hydroxyprogesteron-Caproat |
HMS2230L08 |
BCP16081 |
HY-B0742 |
NSC17592 |
ZINC4083606 |
Tox21_113502 |
Tox21_302333 |
MFCD00072134 |
s4674 |
SBB080822 |
AKOS005267159 |
Tox21_113502_1 |
ACN-037582 |
CCG-268987 |
DB06789 |
GS-3233 |
NCGC00021268-04 |
NCGC00255784-01 |
Pregn-4-ene-3, 17-hydroxy-, hexanoate |
ST075196 |
17alpha-hexanoyloxy-4pregnene-3,20-dione |
Hydroxyprogesterone caproate (JAN/USP/INN) |
Pregn-4-ene-3, 17-(1-oxohexyl)oxy- |
17-Hydroxypregn-4-ene-3,20-dione caproate |
H0994 |
17alpha-Hydroxyprogesterone hexanoate, >=98% |
3,20-Dioxopregn-4-en-17.alpha.-yl caproate |
C08148 |
D00949 |
H10189 |
17-.alpha.-Hexanoyloxypregn-4-ene-3,20-dione |
17alpha-Hydroxypregn-4-ene-3,20-diene Caproate |
17alpha-Hydroxyprogesterone caproate Progestins |
3,20-Dioxopregn-4-en-17.alpha.-yl hexanoate # |
630H568 |
A834188 |
SR-01000003075 |
17.alpha.-Hydroxypregn-4-ene-3,20-dione caproate |
17.alpha.-Hydroxypregn-4-ene-3,20-dione hexanoate |
Q-201222 |
Q3792032 |
SR-01000003075-3 |
Hydroxyprogesterone caproate, United States Pharmacopeia (USP) Reference Standard |
(1S,2R,10R,11S,14R,15S)-14-acetyl-2,15-dimethyl-5-oxotetracyclo8.7.0.0^{2,7}.0^{11,15}heptadec-6-en-14-yl hexanoate |
(10R,13S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopentaaphenanthren-17-yl hexanoate |
(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopentaaphenanthren-17-yl hexanoate;17-Caproxyprogesterone |
Experimental Data
HYDROXYPROGESTERONE CAPROATE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | umol/L | 61.06 | 56.82 | -6.933 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.86 | 15.79 | -0.4039 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 50.43 | 49.66 | -1.533 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 16.6 | 16.24 | -2.181 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 46.64 | 47.87 | 2.632 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 46.24 | 49.59 | 7.252 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
HYDROXYPROGESTERONE CAPROATE
Statistics Data
HYDROXYPROGESTERONE CAPROATE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -0.4039 | 1 | 2 | |
| Drosophila melanogaster | 7.252 | 1 | 4 |
Statistics Data Visualization
HYDROXYPROGESTERONE CAPROATE
