Compound Summary
Compound Information
AMG-517
Compound Name: | AMG-517 |
Compound CID: | 16007367 |
Synonyms: | AMG-517 659730-32-2 AMG 517 AMG517 UNII-172V4FBZ75 More... |
Iupac Name: | N-[4-[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide |
InChI: | InChI=1S/C20H13F3N4O2S/c1-11(28)26-19-27-18-15(3-2-4-16(18)30-19)29-17-9-14(24-10-25-17)12-5-7-13(8-6-12)20(21,22)23/h2-10H,1H3,(H,26,27,28) |
InChIKey: | YUTIXVXZQIQWGY-UHFFFAOYSA-N |
Canonical Smiles: | CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F |
Isomeric Smiles: | CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F |
Molecular Weight: | 430.4 |
Molecular Formula: | C20H13F3N4O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
AMG-517
Molecular Weight: | 430.4 |
Molecular Formula: | C20H13F3N4O2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 30 |
Complexity: | 603 |
Synonyms
AMG-517
| AMG-517 | AMG-517 |
|---|---|
AMG-517 |
659730-32-2 |
AMG 517 |
AMG517 |
UNII-172V4FBZ75 |
Acetamide, N-(4-((6-(4-(trifluoromethyl)phenyl)-4-pyrimidinyl)oxy)-2-benzothiazolyl)- |
CHEMBL229430 |
172V4FBZ75 |
N-4-6-4-(trifluoromethyl)phenylpyrimidin-4-yloxy-1,3-benzothiazol-2-ylacetamide |
N-(4-((6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)oxy)benzodthiazol-2-yl)acetamide |
N-4-({6-4-(trifluoromethyl)phenylpyrimidin-4-yl}oxy)-1,3-benzothiazol-2-ylacetamide |
BD-0082 |
GTPL4129 |
JMC503515 Compound 23 |
SCHEMBL1042780 |
BDBM20557 |
DTXSID90216178 |
HMS3653C07 |
HMS3886D11 |
AOB87374 |
BCP07380 |
EX-A2915 |
2210AH |
s7115 |
ZINC14974132 |
AKOS015994535 |
CCG-269008 |
CS-0980 |
SB19597 |
NCGC00386259-04 |
AC-30947 |
HY-10634 |
US8796328, A |
US8802711, H |
SW219382-1 |
Q27074438 |
N-4-6-4-(TRIFLUOROMETHYL)PHENYL-4-PYRIMIDINYLOXY-2-BENZOTHIAZOLYLACETAMIDE |
N-{4-6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yloxy-benzothiazol-2-yl}-acetamide |
Experimental Data
AMG-517
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Brachionus manjavacas | 1 | umol/L | 0 | NS | 27484416 | Inactive | |||||||
| Brachionus manjavacas | 0.5 | umol/L | 0 | NS | 27484416 | Inactive |
Experimental Data Visualization
AMG-517
Statistics Data
AMG-517
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Brachionus manjavacas | 0 | 1 | 2 |
Statistics Data Visualization
AMG-517
