Compound Summary

  Compound Information
 sulindac

Compound Name:

sulindac

Compound CID:

1548887

Synonyms:

sulindac

Clinoril

38194-50-2

Sulindaco

Sulindacum

More...

Iupac Name:

2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid

InChI:

InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-

InChIKey:

MLKXDPUZXIRXEP-MFOYZWKCSA-N

Canonical Smiles:

CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O

Isomeric Smiles:

CC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O

Molecular Weight:

356.4

Molecular Formula:

C20H17FO3S

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 sulindac

Molecular Weight:

356.4

Molecular Formula:

C20H17FO3S

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

5

Rotatable Bond Count:

4

Heavy Atom Count:

25

Complexity:

616

  Synonyms
 sulindac

sulindac sulindac

sulindac

Clinoril

38194-50-2

Sulindaco

Sulindacum

Aflodac

Arthrocine

Sulreuma

Sulindac sulfoxide

(Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid

Mobilin

cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid

CHEBI:9352

(Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid

cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid

MK 231

MK-231

Algocetil

Artribid

Citireuma

Clisundac

Imbaral

Reumofil

Sulinol

CHEMBL15770

Sudac

2-(1Z)-5-fluoro-1-(4-methanesulfinylphenyl)methylidene-2-methyl-1H-inden-3-ylacetic acid

2-(3Z)-6-fluoro-2-methyl-3-(4-methylsulfinylphenyl)methylideneinden-1-ylacetic acid

NCGC00015970-02

CAS-38194-50-2

DSSTox_CID_3624

Sulindacum INN-Latin

DSSTox_RID_77117

DSSTox_GSID_23624

Sulindaco INN-Spanish

C20H17FO3S

cis-Sulindac

Sulindac (Clinoril)

{(1Z)-5-fluoro-2-methyl-1-4-(methylsulfinyl)benzylidene-1H-inden-3-yl}acetic acid

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

(Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)-benzylidene)-1H-inden-3-yl)acetic acid

Clinoril (TN)

CCRIS 3305

SR-01000075237

32004-68-5

EINECS 253-819-2

BRN 2951842

Moblilin

(Z)-2-5-Fluoro-2-methyl-1-4-(methylsulfinyl)benzylidene-1H-inden-3-ylacetic Acid

2-(5-fluoro-2-methyl-1-{4-(methylsulfinyl)phenylmethylene}inden-3-yl)acetic acid

1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-4-(methylsulfinyl)phenylmethylene-, (1Z)-

EINECS 250-893-8

EINECS 256-402-3

Sulindac USAN:USP:INN:BAN:JAN

Tocris-1707

Prestwick3_000073

Spectrum5_001024

Lopac-S-8139

S 8139

Sulindac, >=98.0%

SCHEMBL4202

SCHEMBL4203

5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid

Lopac0_001070

BSPBio_000285

BSPBio_002890

MLS001056554

SPECTRUM1500556

Sulindac (JP17/USP/INN)

BPBio1_000315

GTPL5425

DTXSID4023624

CHEBI:93811

HMS501O03

cMAP_000021

HMS1921C11

HMS2092K15

HMS2095O07

HMS2231N24

HMS3259K06

HMS3263E22

HMS3414N11

HMS3649P19

HMS3678N09

HMS3712O07

HMS3884K18

Pharmakon1600-01500556

HY-B0008

Tox21_110270

Tox21_301418

Tox21_501070

BDBM50012899

BDBM50103504

CCG-39264

NSC757344

s2007

SBB058181

AKOS015895412

cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidenyl)indene-3-acetic acid

Tox21_110270_1

CS-0569

DB00605

KS-5153

LP01070

NC00540

NSC 757344

NSC-757344

SDCCGSBI-0051040.P005

(Z)-(1)-5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid

(Z)-5-Fluoro-2-methyl-1-4-(methyl-sulfinyl)phenylmethylene-1H-indene-3-acetic acid

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-4-(methylsulfinyl)phenylmethylene-, (1Z)-

IDI1_000601

Sulindac 100 microg/mL in Acetonitrile

NCGC00015970-01

NCGC00015970-03

NCGC00015970-04

NCGC00015970-05

NCGC00015970-06

NCGC00015970-07

NCGC00015970-08

NCGC00015970-11

NCGC00025268-01

NCGC00025268-02

NCGC00025268-03

NCGC00094349-01

NCGC00094349-02

NCGC00255143-01

NCGC00261755-01

NCGC00381714-10

BP-30208

BS166205

LS-14757

SMR000326718

SBI-0051040.P004

Sulindac, meets USP testing specifications

AB00513800

EU-0101070

ST51015123

SW219748-1

U0099

9222-EP2275420A1

9222-EP2277565A2

9222-EP2277566A2

9222-EP2277567A1

9222-EP2277568A2

9222-EP2277569A2

9222-EP2277570A2

9222-EP2280008A2

9222-EP2281815A1

9222-EP2284166A1

9222-EP2292280A1

9222-EP2295055A2

9222-EP2295409A1

9222-EP2298764A1

9222-EP2298765A1

9222-EP2301933A1

9222-EP2305640A2

9222-EP2305652A2

9222-EP2308872A1

9222-EP2311453A1

9222-EP2311827A1

9222-EP2314585A1

9222-EP2314590A1

9222-EP2316829A1

C01531

D00120

AB00052105-07

AB00052105_08

AB00052105_09

Q963093

J-008554

J-012337

SR-01000075237-2

SR-01000075237-3

SR-01000075237-5

SR-01000075237-7

BRD-A13946108-001-04-9

BRD-A13946108-001-08-0

SR-01000075237-13

Sulindac, European Pharmacopoeia (EP) Reference Standard

Sulindac, United States Pharmacopeia (USP) Reference Standard

(S,Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid

(Z)-5-Fluoro-2-methyl-1-(p-methylsulfinyl)benzylidene-1H-indene-3-acetic Acid

(Z)-5-fluoro-2-methyl-1-4-(methylsulfinyl)-phenylmethylene-1H-indene-3-acetic acid

{(1z)-5-fluoro-2-methyl-1-4-(methylsulfinyl)benzylidene-1h-indene-3-yl}acetic acid

2-(3Z)-6-fluoro-2-methyl-3-(4-methylsulfinylphenyl)methyleneinden-1-ylacetic acid

Sulindac|(1Z)-5-Fluoro-2-methyl-1-4-(methylsulfinyl)phenylmethylene-1H-indene-3-acetic acid

  Experimental Data
 sulindac

Species Dosage Unit CG Lifespan(AVG/MED days) TG Lifespan(AVG/MED days) Lifespan Change(AVG/MED%) CG Lifespan(MAX days) TG Lifespan(MAX days) Lifespan Change(MAX%) Significant Strain Gender PubMed Active Label
Caenorhabditis elegans 33 umol/L -6 NS N2 24134630 Inactive
  Experimental Data Visualization
 sulindac

  Statistics Data
 sulindac

Species Lifespan Change(AVG/MED%) Lifespan Change(MAX%) Count Reference Count Data point
Caenorhabditis elegans -6 1 1
  Statistics Data Visualization
 sulindac

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