Compound Summary
Compound Information
cinnarizine
Compound Name: | cinnarizine |
Compound CID: | 1547484 |
Synonyms: | cinnarizine 298-57-7 Stugeron Dimitronal Stutgin More... |
Iupac Name: | 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine |
InChI: | InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+ |
InChIKey: | DERZBLKQOCDDDZ-JLHYYAGUSA-N |
Canonical Smiles: | C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4 |
Isomeric Smiles: | C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4 |
Molecular Weight: | 368.5 |
Molecular Formula: | C26H28N2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
cinnarizine
Molecular Weight: | 368.5 |
Molecular Formula: | C26H28N2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 28 |
Complexity: | 429 |
Synonyms
cinnarizine
| cinnarizine | cinnarizine |
|---|---|
cinnarizine |
298-57-7 |
Stugeron |
Dimitronal |
Stutgin |
Cinarizine |
Dimitron |
Folcodal |
Midronal |
Mitronal |
Stutgeron |
Glanil |
Labyrin |
Lazeta |
Marisan |
Toliman |
Sepan |
Cinazyn |
Cinnarizinum |
Aplactan |
Cinarizina |
Cinnageron |
Cerepar |
R 516 |
1-Cinnamyl-4-(diphenylmethyl)piperazine |
Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)- |
1-Benzhydryl-4-cinnamylpiperazin |
R 1575 |
16699-20-0 |
516 MD |
1-benzhydryl-4-(E)-3-phenylprop-2-enylpiperazine |
(E)-1-Benzhydryl-4-cinnamylpiperazine |
1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine |
1-(diphenylmethyl)-4-(2E)-3-phenylprop-2-en-1-ylpiperazine |
C26H28N2 |
UNII-3DI2E1X18L |
1-Benzhydryl-4-cinnamylpiperazine |
1-trans-Cinnamyl-4-diphenylmethylpiperazine |
1-benzhydryl-4-(E)-cinnamylpiperazine |
CHEMBL43064 |
MLS000028498 |
3DI2E1X18L |
Piperazine, 1-cinnamyl-4-(diphenylmethyl)- |
CHEBI:31403 |
MFCD00056037 |
Cinaperazine |
Libotasin |
Senoger |
SMR000058307 |
Votegol |
Zepamol |
Cero-Aterin |
DSSTox_CID_2821 |
R-1575 |
DSSTox_RID_76744 |
DSSTox_GSID_22821 |
Cinarizina INN-Spanish |
Cinnarizinum INN-Latin |
Processine |
Sedatromin |
Spaderizine |
4-((2E)-3-phenylprop-2-enyl)-1-(diphenylmethyl)piperazine |
Aplexal |
Apotomin |
Carecin |
Cerebolan |
Cinnacet |
Corathiem |
Denapol |
Giganten |
Hilactan |
Ixertol |
Katoseran |
Siptazin |
Stonoron |
Artate |
Eglen |
Olamin |
e-1-benzhydryl-4-cinnamylpiperazine |
Cinnarizine USAN:INN:BAN:JAN |
R-516 |
SR-01000003093 |
EINECS 206-064-8 |
MD 516 |
BRN 0626121 |
Stunarone |
Cinnarizine (JAN/USAN/INN) |
1-Cinnamyl-4-diphenylmethylpiperazine |
N-Benzhydryl-N-cinnamylpiperazine |
NCGC00015246-02 |
CAS-298-57-7 |
Cinnarizine, powder |
Prestwick_115 |
Piperazine, (E)- |
Opera_ID_1776 |
Prestwick2_000278 |
Prestwick3_000278 |
C 5270 |
Lopac0_000314 |
SCHEMBL44957 |
SCHEMBL44958 |
BSPBio_000156 |
MLS001148649 |
MLS002207295 |
MLS002222167 |
ARONIS27007 |
BPBio1_000172 |
GTPL9072 |
1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine |
DTXSID3022821 |
cid_1547484 |
1-(Diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)piperazine |
AOB5321 |
CHEBI:131176 |
HMS1568H18 |
HMS2095H18 |
HMS2234B20 |
HMS3260P10 |
HMS3712H18 |
HMS3885F20 |
component of Emesazine (Salt/Mix) |
EBD32904 |
HY-B1090 |
Tox21_110109 |
Tox21_500314 |
516-MD |
BDBM50017657 |
NSC290687 |
NSC771642 |
SBB057016 |
STK216257 |
ZINC19632891 |
AKOS002134299 |
Stugeron|Dimitronal|Stutgin|Cinarizine |
Tox21_110109_1 |
CCG-204409 |
CS-4656 |
KS-5155 |
LP00314 |
NSC 758400 |
NSC-290687 |
NSC-771642 |
SDCCGSBI-0050302.P002 |
QTL1_000023 |
NCGC00018187-03 |
NCGC00018187-04 |
NCGC00018187-05 |
NCGC00018187-06 |
NCGC00018187-07 |
NCGC00018187-09 |
NCGC00018187-14 |
NCGC00021488-03 |
NCGC00021488-04 |
NCGC00021488-05 |
NCGC00260999-01 |
BC167081 |
LS-15144 |
ST069378 |
EU-0100314 |
S4727 |
1412-EP2275420A1 |
1412-EP2280008A2 |
1412-EP2298764A1 |
1412-EP2298765A1 |
1412-EP2305219A1 |
A16455 |
D01295 |
J10228 |
298C577 |
A820077 |
L001227 |
Q775073 |
1-Benzhydryl-4-3-phenyl-2-propenylpiperazine # |
SR-01000003093-2 |
SR-01000003093-6 |
W-106970 |
W-110442 |
1-benzhydryl-4-(2E)-3-phenylprop-2-enylpiperazine |
BRD-K07220430-001-03-6 |
BRD-K74927006-001-01-2 |
1-di(phenyl)methyl-4-(3-phenylprop-2-enyl)piperazine |
1-(diphenylmethyl)-4-(3-phenylprop-2-en-1-yl)piperazine |
Cinnarizine, European Pharmacopoeia (EP) Reference Standard |
Cinnarizine; 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine |
Experimental Data
cinnarizine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 15 | S | N2 | 24134630 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 15 | S | N2 | 33683565 | Active |
Experimental Data Visualization
cinnarizine
Statistics Data
cinnarizine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 15 | 2 | 2 |
Statistics Data Visualization
cinnarizine
