Compound Summary
Compound Information
WIN 62,577
Compound Name: | WIN 62,577 |
Compound CID: | 15118529 |
Synonyms: | WIN 62,577 WIN-62577 138091-43-7 144177-32-2 (1R,3aS,3bR,15aR,15bS,17aS)-1-ethynyl-15a,17a-dimethyl-2,3,3a,3b,4,5,15,15a,15b,16,17,17a-dodecahydro-1H-benzo4,5imidazo2,1-bcyclopenta5,6naphtho1,2-gquinazolin-1-ol More... |
Iupac Name: | (3R,4S,7S,8R,11S,12R)-8-ethynyl-3,7-dimethyl-18,20,27-triazaheptacyclo[15.11.0.03,15.04,12.07,11.019,27.021,26]octacosa-1(28),15,17,19,21,23,25-heptaen-8-ol |
InChI: | InChI=1S/C29H31N3O/c1-4-29(33)14-12-22-20-10-9-19-15-24-18(16-27(19,2)21(20)11-13-28(22,29)3)17-32-25-8-6-5-7-23(25)30-26(32)31-24/h1,5-8,15,17,20-22,33H,9-14,16H2,2-3H3/t20-,21+,22+,27+,28+,29+/m1/s1 |
InChIKey: | YBCYJDNOPAFFOW-XOAARHKISA-N |
Canonical Smiles: | CC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=NC6=NC7=CC=CC=C7N6C=C5CC34C |
Isomeric Smiles: | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=NC6=NC7=CC=CC=C7N6C=C5C[C@]34C |
Molecular Weight: | 437.6 |
Molecular Formula: | C29H31N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
WIN 62,577
Molecular Weight: | 437.6 |
Molecular Formula: | C29H31N3O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 33 |
Complexity: | 921 |
Synonyms
WIN 62,577
| WIN 62,577 | WIN 62,577 |
|---|---|
WIN 62,577 |
WIN-62577 |
138091-43-7 |
144177-32-2 |
(1R,3aS,3bR,15aR,15bS,17aS)-1-ethynyl-15a,17a-dimethyl-2,3,3a,3b,4,5,15,15a,15b,16,17,17a-dodecahydro-1H-benzo4,5imidazo2,1-bcyclopenta5,6naphtho1,2-gquinazolin-1-ol |
(3R,4S,7S,8R,11S,12R)-8-Ethynyl-3,7-dimethyl-18,20,27-triazaheptacyclo15.11.0.03,15.04,12.07,11.019,27.021,26octacosa-1(28),15,17,19,21,23,25-heptaen-8-ol |
WIN62,577 |
WIN 62,577, solid |
GTPL340 |
MLS002153154 |
win-62,577 |
CHEMBL1256845 |
DTXSID50568483 |
HMS2234A21 |
MFCD00153883 |
ZINC13448419 |
Win 62,577 novel non-peptide nk- |
SMR001230649 |
Q27089225 |
Experimental Data
WIN 62,577
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 7 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
WIN 62,577
Statistics Data
WIN 62,577
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7 | 1 | 1 |
Statistics Data Visualization
WIN 62,577
