Compound Summary
Compound Information
Cycloastragenol
Compound Name: | Cycloastragenol |
Compound CID: | 13943286 |
Synonyms: | Cycloastragenol 78574-94-4 Astramembrangenin Cyclogalegenol Cyclosiversigenin More... |
Iupac Name: | (1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecane-6,9,14-triol |
InChI: | InChI=1S/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21-,22-,23-,26+,27-,28+,29-,30+/m0/s1 |
InChIKey: | WENNXORDXYGDTP-UOUCMYEWSA-N |
Canonical Smiles: | CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)O)O)C |
Isomeric Smiles: | C[C@]12CC[C@@]34C[C@@]35CC[C@@H](C([C@@H]5[C@H](C[C@H]4[C@@]1(C[C@@H]([C@@H]2[C@]6(CC[C@H](O6)C(C)(C)O)C)O)C)O)(C)C)O |
Molecular Weight: | 490.7 |
Molecular Formula: | C30H50O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Cycloastragenol
Molecular Weight: | 490.7 |
Molecular Formula: | C30H50O5 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 35 |
Complexity: | 916 |
Synonyms
Cycloastragenol
| Cycloastragenol | Cycloastragenol |
|---|---|
Cycloastragenol |
78574-94-4 |
Astramembrangenin |
Cyclogalegenol |
Cyclosiversigenin |
Cyclogalegigenin |
UNII-X37D9F2L0V |
X37D9F2L0V |
(2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyltetradecahydro-1H,12H-cyclopentaacyclopropaephenanthrene-4,7,9-triol |
84605-18-5 |
Cyclosieversigenin |
Cycloastragenol, >=98% (HPLC) |
(3beta,6alpha,9beta,16beta,20R,24S)-20,24-epoxy-9,19-cyclolanostane-3,6,16,25-tetrol |
(2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-Hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethylhexadecahydrocyclopentaacyclopropaephenanthrene-4,7,9-triol |
SCHEMBL365107 |
CHEMBL4171632 |
CHEBI:71314 |
WENNXORDXYGDTP-UOUCMYEWSA- |
HY-N1485 |
MFCD24849201 |
s4981 |
ZINC68248924 |
AKOS030524082 |
CCG-269619 |
9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-,(3b,6a,16b,20R,24S)- |
DS-19394 |
C3469 |
CS-0017026 |
A864051 |
Q3979404 |
(3b,6a,16b,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclogalagenin |
(3beta,6alpha,16beta,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol |
(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-15-(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl-7,7,12,16-tetramethylpentacyclo9.7.0.01,3.03,8.012,16octadecane-6,9,14-triol |
(3beta,6alpha,16beta,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol / Astramembrangenin |
Experimental Data
Cycloastragenol
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | umol/L | 16.35 | 18.93 | 0.16 | S | N2 | 31496283 | Active | ||||
| Caenorhabditis elegans | 50 | umol/L | 17.13 | 19.27 | 0.12 | S | N2 | 30449165 | Active |
Experimental Data Visualization
Cycloastragenol
Statistics Data
Cycloastragenol
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.16 | 2 | 2 |
Statistics Data Visualization
Cycloastragenol
