Compound Summary
Compound Information
zaprinast
Compound Name: | zaprinast |
Compound CID: | 135399235 |
Synonyms: | zaprinast 37762-06-4 UNII-GXT25D5DS0 Tocris-0947 GXT25D5DS0 More... |
Iupac Name: | 5-(2-propoxyphenyl)-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one |
InChI: | InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19) |
InChIKey: | REZGGXNDEMKIQB-UHFFFAOYSA-N |
Canonical Smiles: | CCCOC1=CC=CC=C1C2=NC3=NNN=C3C(=O)N2 |
Isomeric Smiles: | CCCOC1=CC=CC=C1C2=NC3=NNN=C3C(=O)N2 |
Molecular Weight: | 271.27 |
Molecular Formula: | C13H13N5O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
zaprinast
Molecular Weight: | 271.27 |
Molecular Formula: | C13H13N5O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 20 |
Complexity: | 400 |
Synonyms
zaprinast
| zaprinast | zaprinast |
|---|---|
zaprinast |
37762-06-4 |
UNII-GXT25D5DS0 |
Tocris-0947 |
GXT25D5DS0 |
5-(2-Propoxyphenyl)-1H-1,2,3triazolo4,5-dpyrimidin-7(4H)-one |
MFCD00214073 |
5-(2-propoxyphenyl)-2H-triazolo4,5-dpyrimidin-7-ol |
NCGC00016105-03 |
M&B-22948 |
CAS-37762-06-4 |
1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo4,5-dpyrimidine-7-one |
DSSTox_CID_25224 |
DSSTox_RID_80761 |
DSSTox_GSID_45224 |
Zaprinastum |
Zaprinastum INN-Latin |
1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one |
M&B 22,948 |
1110670-37-5 |
M and B 22948 |
8-Aza-2-(2-propoxyphenyl)-6-purinone |
Zaprinast INN:BAN |
SR-01000075536 |
EINECS 253-655-1 |
2-o-Propoxyphenyl-8-azapurine-6-one |
2-(o-Propoxyphenyl)-8-azapurin-6-one |
2-(2-Propoxyphenyl)-8-aza-6-purinone |
Zaprinast, solid |
1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo4,5-dpyrimidin-7-one |
Prestwick_655 |
2-o-Propoxyphenyl-8-azapurin-6-on |
Spectrum_001265 |
M&B22948 |
Prestwick0_000335 |
Prestwick1_000335 |
Prestwick2_000335 |
Prestwick3_000335 |
Spectrum2_001447 |
Spectrum3_000933 |
Spectrum4_001032 |
Spectrum5_001023 |
Lopac-Z-0878 |
3,6-Dihydro-5-(o-propoxyphenyl)-7H-v-triazolo(4,5-d)pyrimidin-7-one |
3,6-Dihydro-5-(2-propoxyphenyl)-7H-(1,2,3)truaziki(4,5-d)pyrimidin-7-on |
Lopac0_001240 |
SCHEMBL50328 |
BSPBio_000369 |
BSPBio_001348 |
KBioGR_001583 |
KBioSS_001745 |
MLS000859963 |
CHEMBL28079 |
DivK1c_000584 |
SPECTRUM1501199 |
SPBio_001313 |
SPBio_002290 |
BPBio1_000407 |
GTPL2919 |
SCHEMBL6913739 |
DTXSID8045224 |
BCBcMAP01_000103 |
BDBM14363 |
CHEBI:92215 |
HMS501N06 |
KBio1_000584 |
KBio2_001745 |
KBio2_004313 |
KBio2_006881 |
KBio3_001966 |
AOB5951 |
6-CHLORO-3-INDOLYLACETATE |
NINDS_000584 |
HMS1569C11 |
HMS1791D10 |
HMS1921P15 |
HMS1989D10 |
HMS2090L04 |
HMS2096C11 |
HMS2235N23 |
HMS3263H22 |
HMS3267G07 |
HMS3370J04 |
HMS3402D10 |
HMS3411J20 |
HMS3675J20 |
HMS3713C11 |
Pharmakon1600-01501199 |
HY-B1816 |
Tox21_110306 |
Tox21_501240 |
2103AH |
6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on |
CCG-39177 |
NSC757885 |
ZINC14953365 |
1,4-Dihydro-5-(2-propoxyphenyl)-1,2,3-triazolo(4,5-d)pyrimidin-7-one |
3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo4,5-dpyrimidin-7-one |
6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on IUPAC |
AKOS024458708 |
Tox21_110306_1 |
2-(2-propoxyphenyl)-8-azahypoxanthine |
CCG-205314 |
CCG-220335 |
CCG-222544 |
LP01240 |
NSC 757885 |
NSC-757885 |
SDCCGSBI-0051207.P004 |
7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 1,4-dihydro-5-(2-propoxyphenyl)- |
IDI1_000584 |
SMP1_000321 |
NCGC00016105-01 |
NCGC00016105-02 |
NCGC00016105-04 |
NCGC00016105-05 |
NCGC00016105-08 |
NCGC00024894-01 |
NCGC00024894-02 |
NCGC00024894-03 |
NCGC00024894-04 |
NCGC00024894-08 |
NCGC00094481-01 |
NCGC00094481-02 |
NCGC00261925-01 |
2-(2-Propyloxyphenyl)-8-azapurin-6-one |
SMR000326822 |
SBI-0051207.P002 |
B6516 |
CS-0013862 |
EU-0101240 |
FT-0675894 |
Z 0878 |
AB00052245_02 |
SR-01000597480 |
Q6592076 |
SR-01000075536-1 |
SR-01000075536-4 |
SR-01000075536-5 |
SR-01000597480-1 |
BRD-K12516989-001-01-9 |
BRD-K16542329-001-05-1 |
BRD-K16542329-001-08-5 |
5-(2-propoxyphenyl)-2,3-dihydrotriazolo4,5-epyrimidin-7-one |
5-(2-propoxyphenyl)-2,6-dihydrotriazolo4,5-dpyrimidin-7-one |
5-(2-propoxyphenyl)-3,6-dihydrotriazolo4,5-dpyrimidin-7-one |
5-(2-Propoxy-phenyl)-3,6-dihydro-1,2,3triazolo4,5-dpyrimidin-7-one |
5-(2-propoxyphenyl)-2H,3H,7H-1,2,3triazolo4,5-dpyrimidin-7-one |
3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo4.3.0nona-1,3,6-trien-5-one |
7H-1,2,3-Triazolo4,5-dpyrimidin-7-one, 2,3-dihydro-5-(2-propoxyphenyl)- |
Experimental Data
zaprinast
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
zaprinast
Statistics Data
zaprinast
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3 | 1 | 1 |
Statistics Data Visualization
zaprinast
