Compound Summary
Compound Information
NU-1025
Compound Name: | NU-1025 |
Compound CID: | 135398517 |
Synonyms: | 90417-38-2 Nu 1025 NU1025 8-Hydroxy-2-methylquinazolin-4(3H)-one 8-Hydroxy-2-methylquinazoline-4-one More... |
Iupac Name: | 8-hydroxy-2-methyl-3H-quinazolin-4-one |
InChI: | InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13) |
InChIKey: | YJDAOHJWLUNFLX-UHFFFAOYSA-N |
Canonical Smiles: | CC1=NC2=C(C=CC=C2O)C(=O)N1 |
Isomeric Smiles: | CC1=NC2=C(C=CC=C2O)C(=O)N1 |
Molecular Weight: | 176.17 |
Molecular Formula: | C9H8N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
NU-1025
Molecular Weight: | 176.17 |
Molecular Formula: | C9H8N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 13 |
Complexity: | 262 |
Synonyms
NU-1025
| NU-1025 | NU-1025 |
|---|---|
90417-38-2 |
Nu 1025 |
NU1025 |
8-Hydroxy-2-methylquinazolin-4(3H)-one |
8-Hydroxy-2-methylquinazoline-4-one |
NU-1025 |
NSC 696807 |
8-hydroxy-2-methyl-1H-quinazolin-4-one |
8-Hydroxy-2-methyl-3H-quinazolin-4-one |
8-HYDROXY-2-METHYL-4(3H)-QUINAZOLINONE |
NSC-696807 |
X5ZL2C7V9B |
8-HYDROXY-2-METHYL-3-HYDRO-QUINAZOLIN-4-ONE |
8-hydroxy-2-methylquinazolin-4(1H)-one |
CHEMBL123904 |
4(1H)-Quinazolinone, 8-hydroxy-2-methyl- |
CHEBI:75399 |
4pax |
8-Hydroxy-2-methylquinazolin-43H-one |
NU1 |
4pnm |
Nu 1064 |
Tocris-1401 |
UNII-X5ZL2C7V9B |
SCHEMBL215529 |
DTXSID20238166 |
HMS3267F20 |
HMS3412M16 |
HMS3676M16 |
HMS3886J17 |
BCP27646 |
BDBM50068774 |
CID 63306 |
NSC696807 |
s7730 |
ZINC18145500 |
AKOS006273983 |
BCP9001000 |
CCG-266404 |
DB02690 |
NU-1025;NU1025 |
NCGC00025146-01 |
NCGC00025146-05 |
NCGC00390481-01 |
AS-63886 |
HY-15044 |
NCI60_034479 |
8-Hydroxy-2-methylquinazolin-4-3H-one |
DB-057203 |
NU-1025, >=97% (HPLC), solid |
CS-0003717 |
FT-0642169 |
EC-000.2422 |
D95563 |
8-hydroxy-2-methyl-1,4-dihydroquinazolin-4-one |
8-hydroxy-2-methyl-3,4-dihydroquinazolin-4-one |
8-hydroxy-2-methyl-1H-quinazolin-4-one;NU1025 |
A843539 |
SR-01000597557 |
J-519442 |
SR-01000597557-1 |
8-Hydroxy-2-methyl-3H-quinazolin-4-one (NU1025) |
BRD-K48692744-001-01-2 |
Q27093640 |
PARP Inhibitor VI, NU1025 - CAS 90417-38-2 |
Experimental Data
NU-1025
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | umol/L | 1.24 | NS | N2 | 30970250 | Inactive |
Experimental Data Visualization
NU-1025
Statistics Data
NU-1025
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1.24 | 1 | 1 |
Statistics Data Visualization
NU-1025
