Compound Summary
Compound Information
acyclovir
Compound Name: | acyclovir |
Compound CID: | 135398513 |
Synonyms: | acyclovir Aciclovir Acycloguanosine 59277-89-3 Zovirax More... |
Iupac Name: | 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one |
InChI: | InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15) |
InChIKey: | MKUXAQIIEYXACX-UHFFFAOYSA-N |
Canonical Smiles: | C1=NC2=C(N1COCCO)N=C(NC2=O)N |
Isomeric Smiles: | C1=NC2=C(N1COCCO)N=C(NC2=O)N |
Molecular Weight: | 225.2 |
Molecular Formula: | C8H11N5O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
acyclovir
Molecular Weight: | 225.2 |
Molecular Formula: | C8H11N5O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 16 |
Complexity: | 308 |
Synonyms
acyclovir
| acyclovir | acyclovir |
|---|---|
acyclovir |
Aciclovir |
Acycloguanosine |
59277-89-3 |
Zovirax |
Vipral |
Virorax |
Wellcome-248U |
9-(2-Hydroxyethoxy)methylguanine |
Aciclovirum |
2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one |
Zovir |
Sitavig |
9-(2-Hydroxyethoxy)methylguanine |
Acyclovir-side chain-2-3H |
9-HYROXYETHOXYMETHYLGUANINE |
W-248-U |
9-((2-Hydroxyethoxy)methyl)guanine |
UNII-X4HES1O11F |
2-Amino-9-(2-hydroxyethoxy)methyl-1,9-dihydro-6H-purin-6-one |
NSC 645011 |
CHEBI:2453 |
2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
Acyclovir (Aciclovir) |
2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one |
6H-Purin-6-one, 2-amino-1,9-dihydro-9-(2-hydroxyethoxy)methyl- |
Zovirax (TN) |
MFCD00057880 |
9-(2-Hydroxyethoxy)-methylguanine |
2-Amino-1,9-dihydro-9-(2-hydroxyethoxy)methyl-6H-purin-6-one |
2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one |
X4HES1O11F |
MLS000069633 |
141294-79-3 |
Activir |
2-amino-9-(2-hydroxyethoxymethyl)purin-6-ol |
9-(2-Hydroxyethoxymethyl)guanine |
NSC645011 |
NSC-645011 |
AC2 |
2-amino-9-((2-hydroxyethoxy)methyl)-3H-purin-6(9H)-one |
NCGC00015061-02 |
Aciclovirum Latin |
Aciclovier |
Hascovir |
SMR000058225 |
Genvir |
Maynar |
Zyclir |
2-amino-9-(2-hydroxyethoxy)methyl-6,9-dihydro-3H-purin-6-one |
CAS-59277-89-3 |
6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)- |
6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)- |
DSSTox_CID_2556 |
DSSTox_RID_76626 |
Aciclovirum INN-Latin |
DSSTox_GSID_22556 |
2-amino-9-(2-hydroxyethoxy)methylhydropurin-6-one |
Acicloftal |
Cargosil |
Viropump |
AcycloFoam |
2-amino-9-(2-hydroxyethoxy)methyl-3,9-dihydro-6H-purin-6-one |
Acic |
BW-248U |
2-amino-9-{(2-hydroxyethyl)oxymethyl}-1,9-dihydro-6H-purin-6-one |
Acyclo-V |
Acyclovir Lauriad |
DRG-0008 |
Acyclovir (USP) |
BW 248U |
CCRIS 1953 |
HSDB 6511 |
SR-01000075540 |
Acyclovir USAN:USP |
EINECS 261-685-1 |
ACV & Pluronic F-68 |
Acyclovir & Pluronic F-68 |
Cyclovir |
Poviral |
Sitavir |
2-amino-9-((2-hydroxyethoxy)methyl)-3,9-dihydro-6H-purin-6-one |
Prestwick_6 |
ACYCLOVIR-SIDECHAIN-2-3H |
1pwy |
Aciclovir INN |
BW-248-U |
Sitavig (TN) |
Spectrum_001739 |
Opera_ID_1674 |
Prestwick0_000086 |
Prestwick1_000086 |
Prestwick2_000086 |
Prestwick3_000086 |
Spectrum2_001563 |
Spectrum3_001874 |
Spectrum4_000225 |
Spectrum5_001093 |
Lopac-A-4669 |
Aciclovir (JP17/INN) |
CHEMBL184 |
A 4669 |
SCHEMBL3175 |
Lopac0_000037 |
BSPBio_000012 |
BSPBio_003348 |
KBioGR_000889 |
KBioSS_002219 |
ARONIS27002 |
BIDD:GT0646 |
DivK1c_000185 |
SPECTRUM1503603 |
SPBio_001466 |
SPBio_001951 |
BPBio1_000014 |
GTPL4829 |
SCHEMBL9828560 |
9(2-hydroxyethoxymethyl)guanine |
DTXSID1022556 |
HMS500J07 |
KBio1_000185 |
KBio2_002219 |
KBio2_004787 |
KBio2_007355 |
KBio3_002850 |
NINDS_000185 |
HMS1568A14 |
HMS1922E08 |
HMS2090G09 |
HMS2095A14 |
HMS2234K21 |
HMS3259N10 |
HMS3260G15 |
HMS3269M15 |
HMS3372K02 |
HMS3413D21 |
HMS3655C14 |
HMS3677D21 |
HMS3712A14 |
Pharmakon1600-01503603 |
BCP11036 |
EBD48195 |
ZINC1530555 |
9-(2-hydroxyethoxy methyl) guanine |
Tox21_110075 |
Tox21_500037 |
69657-51-8 (Na salt) |
BBL009642 |
BDBM50021776 |
BDBM50103518 |
CCG-39909 |
NSC758477 |
NSC780378 |
s1807 |
SBB063281 |
STK796771 |
STL257059 |
STL301862 |
AKOS000656213 |
AKOS015995680 |
AKOS022135433 |
Tox21_110075_1 |
AC-8068 |
CS-1353 |
DB00787 |
KS-1027 |
LP00037 |
MCULE-2703274259 |
NC00717 |
NSC-758477 |
NSC-780378 |
SDCCGSBI-0050026.P003 |
IDI1_000185 |
SMP1_000007 |
NCGC00015061-01 |
NCGC00015061-03 |
NCGC00015061-04 |
NCGC00015061-05 |
NCGC00015061-06 |
NCGC00015061-07 |
NCGC00015061-08 |
NCGC00015061-09 |
NCGC00015061-10 |
NCGC00015061-12 |
NCGC00015061-13 |
NCGC00015061-28 |
NCGC00015061-29 |
NCGC00022426-03 |
NCGC00093555-01 |
NCGC00093555-02 |
NCGC00093555-03 |
NCGC00093555-04 |
NCGC00167756-01 |
NCGC00167756-02 |
NCGC00260722-01 |
NCGC00381719-03 |
HY-17422 |
ST024744 |
SY051130 |
Acycloguanosine, >=99% (HPLC), powder |
AB0012294 |
AB0068584 |
Aciclovir 1.0 mg/ml in Dimethyl Sulfoxide |
AM20100442 |
EU-0100037 |
FT-0621607 |
FT-0657847 |
SW196324-3 |
6383-EP2270005A1 |
6383-EP2305243A1 |
6383-EP2305640A2 |
6383-EP2305808A1 |
6383-EP2314582A1 |
6383-EP2314585A1 |
C06810 |
D00222 |
J10243 |
32284-EP2281815A1 |
32284-EP2301933A1 |
32284-EP2311827A1 |
277A893 |
A832236 |
A935190 |
Q147101 |
Q-200591 |
SR-01000075540-1 |
SR-01000075540-3 |
SR-01000075540-5 |
2-amino-9-(2-hydroxyethoxy)methyl-9H-purin-6-ol |
2-azanyl-9-(2-hydroxyethyloxymethyl)-3H-purin-6-one |
BRD-K32318651-001-17-9 |
Aciclovir, British Pharmacopoeia (BP) Reference Standard |
F2173-0946 |
Aciclovir, European Pharmacopoeia (EP) Reference Standard |
2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one |
Acyclovir, United States Pharmacopeia (USP) Reference Standard |
2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one (ACV) |
2-Amino-9-(2-hydroxyethoxy)methyl-1,9-dihydro-6H-purin-6-one # |
ACV; Acycloguanosine; Acyclovir; NSC 645011; NSC-645011; NSC645011 |
Acyclovir, Pharmaceutical Secondary Standard; Certified Reference Material |
Aciclovir for peak identification 1, European Pharmacopoeia (EP) Reference Standard |
Aciclovir for peak identification 2, European Pharmacopoeia (EP) Reference Standard |
Aciclovir for system suitability, European Pharmacopoeia (EP) Reference Standard |
Experimental Data
acyclovir
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -9 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
acyclovir
Statistics Data
acyclovir
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -9 | 1 | 1 |
Statistics Data Visualization
acyclovir
