Compound Summary
Compound Information
148451-96-1
Compound Name: | 148451-96-1 |
Compound CID: | 132837 |
Synonyms: | 148451-96-1 L-732,138 L-732138 3,5-Bis(trifluoromethyl)benzyl N-acetyltryptophan N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester More... |
Iupac Name: | [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate |
InChI: | InChI=1S/C22H18F6N2O3/c1-12(31)30-19(8-14-10-29-18-5-3-2-4-17(14)18)20(32)33-11-13-6-15(21(23,24)25)9-16(7-13)22(26,27)28/h2-7,9-10,19,29H,8,11H2,1H3,(H,30,31)/t19-/m0/s1 |
InChIKey: | BYYQYXVAWXAYQC-IBGZPJMESA-N |
Canonical Smiles: | CC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F |
Isomeric Smiles: | CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F |
Molecular Weight: | 472.4 |
Molecular Formula: | C22H18F6N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
148451-96-1
Molecular Weight: | 472.4 |
Molecular Formula: | C22H18F6N2O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 33 |
Complexity: | 677 |
Synonyms
148451-96-1
| 148451-96-1 | 148451-96-1 |
|---|---|
148451-96-1 |
L-732,138 |
L-732138 |
3,5-Bis(trifluoromethyl)benzyl N-acetyltryptophan |
N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester |
L 732138 |
3,5-bis(trifluoromethyl)benzyl acetyl-L-tryptophanate |
3,5-bis(trifluoromethyl)phenylmethyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate |
L732138 |
CHEMBL22870 |
L-Tryptophan, N-acetyl-, 3,5-bis(trifluoromethyl)phenylmethyl ester |
MFCD00237267 |
N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester |
L-Tryptophan, N-acetyl-, (3,5-bis(trifluoromethyl)phenyl)methyl ester |
3,5-Bis(tfm)Bz nactrp |
AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER |
N-Acetyl-L-trp-3,5-bistrifluoromethylbenzyl ester |
N-Acetyl-L-tryptophan-3,5-bistrifluoromethylbenzyl ester |
Tocris-0868 |
Lopac-A-5330 |
Lopac0_000028 |
MLS002172463 |
BIDD:GT0377 |
GTPL9461 |
SCHEMBL3682000 |
BDBM21016 |
DTXSID20163989 |
HMS2234A11 |
HMS3260E17 |
ZINC598586 |
Tox21_500028 |
AKOS015898307 |
CCG-204124 |
LP00028 |
SDCCGSBI-0050017.P002 |
NCGC00015066-01 |
NCGC00024832-01 |
NCGC00024832-02 |
NCGC00024832-03 |
NCGC00024832-04 |
NCGC00024832-05 |
NCGC00260713-01 |
BS-15443 |
SMR001254094 |
HY-101249 |
B6478 |
CS-0021036 |
EU-0100028 |
S0772 |
A 5330 |
D81775 |
AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYLESTER |
SR-01000075194 |
SR-01000597431 |
SR-01000075194-1 |
SR-01000597431-1 |
N-acetyl-l-tryptophan 3,5-bis(trifluoromethyl) benzyl ester |
N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzylester |
N-Acetyl-L-trytophan 3,5-bis(trifluoromethyl)benzyl ester |
(S)-3,5-bis(trifluoromethyl)benzyl 2-acetamido-3-(1H-indol-3-yl)propanoate |
N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester, >=99% (TLC), powder |
Experimental Data
148451-96-1
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
148451-96-1
Statistics Data
148451-96-1
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5 | 1 | 1 |
Statistics Data Visualization
148451-96-1
