Compound Summary
Compound Information
Ethopropazine hydrochloride
Compound Name: | Ethopropazine hydrochloride |
Compound CID: | 122824 |
Synonyms: | Ethopropazine hydrochloride Profenamine hydrochloride 1094-08-2 Lysivane Pardisol More... |
Iupac Name: | N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride |
InChI: | InChI=1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H |
InChIKey: | VXPCQISYVPFYRK-UHFFFAOYSA-N |
Canonical Smiles: | CCN(CC)C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Isomeric Smiles: | CCN(CC)C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Molecular Weight: | 348.9 |
Molecular Formula: | C19H25ClN2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Ethopropazine hydrochloride
Molecular Weight: | 348.9 |
Molecular Formula: | C19H25ClN2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 23 |
Complexity: | 322 |
Synonyms
Ethopropazine hydrochloride
| Ethopropazine hydrochloride | Ethopropazine hydrochloride |
|---|---|
Ethopropazine hydrochloride |
Profenamine hydrochloride |
1094-08-2 |
Lysivane |
Pardisol |
Parfezin |
Parphezein |
Dibutil |
Profenamine HCl |
Profenamine monohydrochloride |
Ethopropazine HCl |
Isothazine hydrochloride |
Parsidol hydrochloride |
Parsidol monohydrochloride |
10-(2-(Diethylamino)propyl)phenothiazine monohydrochloride |
N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethylamine monohydrochloride |
ethopropazine monohydrochloride |
CHEMBL1200970 |
CHEBI:31568 |
N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride |
Parphezin |
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride |
DSSTox_CID_25347 |
DSSTox_RID_80815 |
DSSTox_GSID_45347 |
Parsidol (VAN) |
Lysivane hydrochloride |
10-(2-(Diethylamino)propyl)-phenothiazin Hydrochloride |
N,N-diethyl-alpha-methyl-10H-phenothiazine-10-ethylamine hydrochloride |
Dibutil hydrochloride |
EINECS 214-134-4 |
NSC 64074 |
NSC 169467 |
diethyl(1-methyl-2-phenothiazin-10-ylethyl)amine, chloride |
SR-05000001626 |
PROPHENAMINE HYDROCHLORIDE |
10H-Phenothiazine-10-ethanamine,N-diethyl-.alpha.-methyl-, monohydrochloride |
Ethopropazine hydrochloride USP |
Parsidol (TN) |
Prestwick_195 |
EINECS 256-019-1 |
l-10-(2-Diethylaminopropyl)phenothiazine hydrochloride |
NCGC00016562-01 |
10-Phenothiazineethylamine, N,N-diethyl-alpha-methyl-, hydrochloride |
CAS-1094-08-2 |
42957-54-0 |
SCHEMBL123703 |
SPECTRUM1500293 |
10-2-(Diethylamino)propylphenothiazine hydrochloride |
DTXSID4045347 |
Profenamine hydrochloride (JAN) |
HMS1570H21 |
HMS1920O04 |
Pharmakon1600-01500293 |
BCP12225 |
NSC64074 |
Phenothiazine, 10-(2-(diethylamino)propyl)-, monohydrochloride |
Tox21_110496 |
Tox21_500873 |
CCG-40202 |
MFCD00012653 |
NSC-64074 |
NSC169467 |
NSC757029 |
SBB057672 |
10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl-, monohydrochloride |
AKOS015901042 |
Tox21_110496_1 |
LP00873 |
MCULE-2860573503 |
NSC-169467 |
NSC-757029 |
NCGC00094678-01 |
NCGC00094678-02 |
NCGC00178860-06 |
NCGC00261558-01 |
DB-040867 |
FT-0625740 |
ST51006789 |
D01118 |
Ethopropazine hydrochloride, >=98% (HPLC), powder |
SR-05000001626-2 |
Q27114444 |
10H-Phenothiazine-10-ethanamine,N,N-diethyl-a-methyl-,hydrochloride(1:1) |
Ethopropazine Hydrochloride;Profenamine HCl; Ethopropazine HCl; 10-2-diethylaminopropylphenothiazine |
Experimental Data
Ethopropazine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10 | umol/L | 15.38 | 14.75 | -4.087 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 16.41 | 15.81 | -3.601 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Ethopropazine hydrochloride
Statistics Data
Ethopropazine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3.601 | 1 | 2 |
Statistics Data Visualization
Ethopropazine hydrochloride
