Compound Summary
Compound Information
ZD7114
Compound Name: | ZD7114 |
Compound CID: | 121877 |
Synonyms: | ZD7114 ICI D7114 UNII-EF5S87KTK2 EF5S87KTK2 129689-30-1 More... |
Iupac Name: | 2-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethoxy]phenoxy]-N-(2-methoxyethyl)acetamide |
InChI: | InChI=1S/C22H30N2O6/c1-27-13-12-24-22(26)17-30-21-9-7-20(8-10-21)28-14-11-23-15-18(25)16-29-19-5-3-2-4-6-19/h2-10,18,23,25H,11-17H2,1H3,(H,24,26)/t18-/m0/s1 |
InChIKey: | RVMBDLSFFNKKLG-SFHVURJKSA-N |
Canonical Smiles: | COCCNC(=O)COC1=CC=C(C=C1)OCCNCC(COC2=CC=CC=C2)O |
Isomeric Smiles: | COCCNC(=O)COC1=CC=C(C=C1)OCCNC[C@@H](COC2=CC=CC=C2)O |
Molecular Weight: | 418.5 |
Molecular Formula: | C22H30N2O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
ZD7114
Molecular Weight: | 418.5 |
Molecular Formula: | C22H30N2O6 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 15 |
Heavy Atom Count: | 30 |
Complexity: | 439 |
Synonyms
ZD7114
| ZD7114 | ZD7114 |
|---|---|
ZD7114 |
ICI D7114 |
UNII-EF5S87KTK2 |
EF5S87KTK2 |
129689-30-1 |
Zeneca ZD7114 |
Acetamide, 2-(4-(2-((2-hydroxy-3-phenoxypropyl)amino)ethoxy)phenoxy)-N-(2-methoxyethyl)-, (S)- |
ZD 7114 |
(S)-4-(2-Hydroxy-3-phenoxypropylaminoethoxy)-N-(2-methoxyethyl)phenoxyacetamide |
2-4-2-(2S)-2-hydroxy-3-phenoxypropylaminoethoxyphenoxy-N-(2-methoxyethyl)acetamide |
SCHEMBL304881 |
CHEMBL1788312 |
DTXSID50926463 |
ICI-D-7114 |
ZINC3793213 |
ZD-7114 |
NCGC00163153-01 |
NCGC00163153-04 |
(S)-2-(4-(2-((2-Hydroxy-3-phenoxypropyl)amino)ethoxy)phenoxy)-N-(2-methoxyethyl)acetamide |
2-(4-{2-(2-Hydroxy-3-phenoxypropyl)aminoethoxy}phenoxy)-N-(2-methoxyethyl)ethanimidic acid |
Experimental Data
ZD7114
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 43.17 | 46.41 | 7.506 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 44.63 | 47.8 | 7.11 | S | FEMALES | 33008901 | Active |
Experimental Data Visualization
ZD7114
Statistics Data
ZD7114
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 7.506 | 1 | 2 |
Statistics Data Visualization
ZD7114
