Compound Summary
Compound Information
Silydianin
Compound Name: | Silydianin |
Compound CID: | 11982272 |
Synonyms: | Silydianin Silidianin 29782-68-1 UNII-7P89L7W179 7P89L7W179 More... |
Iupac Name: | (1R,3R,6R,7R,10R)-3-hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-[(2R,3R)-3,5,7-trihydroxy-4-oxo-2,3-dihydrochromen-2-yl]-4-oxatricyclo[4.3.1.03,7]dec-8-en-2-one |
InChI: | InChI=1S/C25H22O10/c1-33-16-4-9(2-3-14(16)27)18-11-7-12(20-13(18)8-34-25(20,32)24(11)31)23-22(30)21(29)19-15(28)5-10(26)6-17(19)35-23/h2-7,11,13,18,20,22-23,26-28,30,32H,8H2,1H3/t11-,13-,18+,20+,22+,23-,25-/m1/s1 |
InChIKey: | CYGIJEJDYJOUAN-JSGXPVSSSA-N |
Canonical Smiles: | COC1=C(C=CC(=C1)C2C3COC4(C3C(=CC2C4=O)C5C(C(=O)C6=C(C=C(C=C6O5)O)O)O)O)O |
Isomeric Smiles: | COC1=C(C=CC(=C1)[C@@H]2[C@H]3CO[C@@]4([C@H]3C(=C[C@H]2C4=O)[C@@H]5[C@H](C(=O)C6=C(C=C(C=C6O5)O)O)O)O)O |
Molecular Weight: | 482.4 |
Molecular Formula: | C25H22O10 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Silydianin
Molecular Weight: | 482.4 |
Molecular Formula: | C25H22O10 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 10 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 35 |
Complexity: | 935 |
Synonyms
Silydianin
| Silydianin | Silydianin |
|---|---|
Silydianin |
Silidianin |
29782-68-1 |
UNII-7P89L7W179 |
7P89L7W179 |
(1R,3R,6R,7R,10R)-3-hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-(2R,3R)-3,5,7-trihydroxy-4-oxo-2,3-dihydrochromen-2-yl-4-oxatricyclo4.3.1.03,7dec-8-en-2-one |
(1S,3S,6R,7S,10R)-3-Hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-(2R,3R)-3,5,7-trihydroxy-4-oxo-2,3-dihydrochromen-2-yl-4-oxatricyclo4.3.1.03,7dec-8-en-2-one |
Silidianine INN-French |
Silidianinum INN-Latin |
Silidianina INN-Spanish |
EINECS 249-848-5 |
Silydianin, analytical standard |
CHEMBL2397733 |
DTXSID70858696 |
HY-N0646 |
ZINC33650025 |
AC-34761 |
AS-56229 |
CS-0009672 |
X1233 |
782S681 |
BRD-K52002287-001-01-0 |
Q27268678 |
Silydianin, United States Pharmacopeia (USP) Reference Standard |
(+)-2,3alpha,3aalpha,7a-Tetrahydro-7aalpha-hydroxy-8-(4-hydroxy-3-methoxyphenyl)-4-(3alpha,5,7-trihydroxy-4-oxo-2beta-chromanyl)-3,6-methanobenzofuran-7(6alphaH)-one |
(3R,3aR,6R,7aR,8R)-7a-Hydroxy-8-(4-hydroxy-3-methoxyphenyl)-4-((2R,3R)-3,5,7-trihydroxy-4-oxochroman-2-yl)-3,3a,6,7a-tetrahydro-3,6-methanobenzofuran-7(2H)-one |
Experimental Data
Silydianin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10 | umol/L | 21.25 | 22.5 | 0.06 | S | N2 | 28039083 | Active | ||||
| Caenorhabditis elegans | 10 | umol/L | 5.88 | S | N2 | 33683565 | Active |
Experimental Data Visualization
Silydianin
Statistics Data
Silydianin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.88 | 2 | 2 |
Statistics Data Visualization
Silydianin
