Compound Summary
Compound Information
R(+)-Terguride
Compound Name: | R(+)-Terguride |
Compound CID: | 11957722 |
Synonyms: | R(+)-Terguride 3-(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo4,3-fgquinoline-9-yl-1,1-diethylurea NCGC00094476-03 Biomol-NT_000081 Lopac0_001234 More... |
Iupac Name: | 3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea |
InChI: | InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16-,18-/m1/s1 |
InChIKey: | JOAHPSVPXZTVEP-QGPMSJSTSA-N |
Canonical Smiles: | CCN(CC)C(=O)NC1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)C |
Isomeric Smiles: | CCN(CC)C(=O)N[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)C |
Molecular Weight: | 340.5 |
Molecular Formula: | C20H28N4O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
R(+)-Terguride
Molecular Weight: | 340.5 |
Molecular Formula: | C20H28N4O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 25 |
Complexity: | 494 |
Synonyms
R(+)-Terguride
| R(+)-Terguride | R(+)-Terguride |
|---|---|
R(+)-Terguride |
3-(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo4,3-fgquinoline-9-yl-1,1-diethylurea |
NCGC00094476-03 |
Biomol-NT_000081 |
Lopac0_001234 |
BPBio1_001406 |
CHEMBL1480516 |
CHEBI:92105 |
CCG-205308 |
NCGC00094476-01 |
NCGC00094476-02 |
EU-0101234 |
N-(6-Methylergolin-8beta-yl)-N,N-diethylurea |
SR-01000076220 |
SR-01000076220-1 |
BRD-K05901394-001-01-1 |
Q27163897 |
R(+)-N,N-Diethyl-N(8alpha)-6-methylergolin-8-ylurea |
88293-83-8 |
Experimental Data
R(+)-Terguride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 18 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
R(+)-Terguride
Statistics Data
R(+)-Terguride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 18 | 1 | 1 |
Statistics Data Visualization
R(+)-Terguride
